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Neurochemistry International, ISSN 0197-0186, 11/2019, Volume 130, p. 104331
In the last decade tremendous progress has been made in understanding how the immune system reacts to insults. During this progress it became obvious that... 
Immunometabolism | Neuroinflammation | Neurodegeneration | Microglia
Journal Article
Nature, ISSN 0028-0836, 09/2017, Volume 549, Issue 7672, pp. 389 - 393
The pathophysiology of neurodegenerative diseases is poorly understood and there are few therapeutic options. Neurodegenerative diseases are characterized by... 
DENDRITIC CELLS | PATTERN | LANGERHANS CELL HISTIOCYTOSIS | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | KINASE | MICE | MODEL | ERDHEIM-CHESTER-DISEASE | EXPRESSION | Microglia - metabolism | Clone Cells - enzymology | Humans | Male | Myeloid Progenitor Cells - enzymology | Extracellular Signal-Regulated MAP Kinases - metabolism | MAP Kinase Signaling System | Erythroid Precursor Cells - enzymology | Histiocytosis - pathology | Microglia - pathology | Female | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Histiocytosis - enzymology | Myeloid Progenitor Cells - metabolism | Neurodegenerative Diseases - pathology | Macrophages - pathology | Microglia - enzymology | Neurodegenerative Diseases - genetics | Myeloid Progenitor Cells - pathology | Histiocytosis - metabolism | Neurodegenerative Diseases - metabolism | Clone Cells - metabolism | Macrophages - enzymology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Erythroid Precursor Cells - pathology | Macrophages - metabolism | Animals | Clone Cells - pathology | Proto-Oncogene Proteins B-raf - genetics | Histiocytosis - genetics | Erythroid Precursor Cells - metabolism | Mosaicism | Mice | Mutation | Neurodegenerative Diseases - enzymology | Physiological aspects | Nervous system | Development and progression | Degeneration | Genetic aspects | Research | Histiocytosis | Mitogen-activated protein kinases | Intervention | Disease | Stem cell transplantation | Activation | Genomes | Kinases | Macrophages | Neuronal-glial interactions | Genotype & phenotype | Allografts | Neurodegeneration | Rodents | Bone marrow | Ataxia | Alzheimer's disease | Myeloid cells | Cytokines | Neurodegenerative diseases | Fetuses | Extracellular signal-regulated kinase | MAP kinase | Cell lineage | Gene expression | Patients | Amyloid precursor protein | Microglia | Organogenesis | Diseases | Neurological diseases | Gliosis | Stem cells | Neural stem cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 51, pp. 13051 - 13056
TNF is a multifunctional cytokine involved in autoimmune disease pathogenesis that exerts its effects through two distinct TNF receptors, TNFR1 and TNFR2.... 
EAE | Neuroinflammation | Humanized mice | T regulatory cells | TNF/TNFR2 | INFECTIONS | MULTIDISCIPLINARY SCIENCES | humanized mice | SUPPRESSION | FACTOR RECEPTOR | FACTOR-ALPHA | PATHOGENESIS | neuroinflammation | NECROSIS-FACTOR TNF | INFLAMMATION | MICE | DIFFERENTIATION | EXPRESSION | Central Nervous System - metabolism | Receptors, Tumor Necrosis Factor, Type II - physiology | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Central Nervous System - pathology | Encephalomyelitis, Autoimmune, Experimental - immunology | Central Nervous System - immunology | Mice, Knockout | T-Lymphocytes, Regulatory - immunology | Animals | Autoimmunity - immunology | Tumor Necrosis Factor-alpha - physiology | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Mice | Disease Models, Animal | Physiological aspects | Cellular signal transduction | Neural circuitry | T cells | Observations | Tumor necrosis factor receptors | Phenotypes | Deactivation | Immune response | Cytokines | Encephalomyelitis | Pathogenesis | Immunoregulation | Helper cells | T cell receptors | Lymphocytes T | Inactivation | Experimental allergic encephalomyelitis | Molecules | Signaling | Receptors | CTLA-4 protein | Tumor necrosis factor | Rodents | CD25 antigen | Foxp3 protein | Autoimmune diseases | Biological Sciences | TNFR2 | TNF
Journal Article
Acta Neuropathologica Communications, ISSN 2051-5960, 2016, Volume 4, Issue 1, p. 102
Journal Article
ACTA NEUROPATHOLOGICA COMMUNICATIONS, ISSN 2051-5960, 07/2019, Volume 7, Issue 1, pp. 106 - 6
[...]experiments undertaken in mice demonstrate that overexpression of interferon in the CNS results in neuropathology reminiscent of that seen in certain type... 
Microgliosis | ALPHA | COGNITION | White matter | NEUROSCIENCES | Corpus callosum | Microglia | INTERFERONOPATHY | Type I interferon | Usp18 | DIFFUSION | Behavior | Magnet resonance spectroscopy | Phagocytosis | Biological response modifiers | Proteases | Interferon | Brain | Neurosciences | Young adults | Disease | Histology | Mutation | Age
Journal Article
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