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Clinical Cancer Research, ISSN 1078-0432, 09/2017, Volume 23, Issue 17, pp. 5101 - 5111
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 12/2015, Volume 14, Issue 12 Supplement 2, pp. C19 - C19
Journal Article
JCO precision oncology, ISSN 2473-4284, 2019, Volume 3
Genomic alterations in blood-derived circulating tumor DNA (ctDNA) from patients with colorectal cancers were correlated with clinical outcomes.... 
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e44146
Activating K-RAS mutations occur at a frequency of 90% in pancreatic cancer, and to date no therapies exist targeting this oncogene. K-RAS signals via... 
BREAST-CANCER | SIGNALING PATHWAYS | CANCER CELLS | ONCOGENIC RAS | DUCTAL ADENOCARCINOMA | VASCULATURE | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | KINASE | GROWTH | ANTITUMOR-ACTIVITY | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Humans | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Gene Knockdown Techniques | Mitogen-Activated Protein Kinase Kinases - metabolism | HEK293 Cells | Female | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Pancreatic Neoplasms - pathology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Pancreatic Neoplasms - enzymology | Pancreatic Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Mutation - genetics | Sulfonamides - pharmacology | Indazoles - pharmacology | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Models, Biological | Cell Line, Tumor | Benzimidazoles - pharmacology | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Ras genes | Gene mutations | Pancreatic cancer | Physiological aspects | Genetic aspects | Research | Risk factors | Drugs | Biomedical research | Disease | Clinical trials | Oncology | Drug delivery | Kinases | Cancer therapies | K-Ras protein | Signal transduction | Pathways | Cell cycle | Xenografts | Tumorigenesis | Inhibition | Medical research | MAP kinase | Data processing | Breast cancer | Maintenance | 1-Phosphatidylinositol 3-kinase | Signaling | Models | In vivo methods and tests | Mutation | Tumors | Cancer
Journal Article
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2019, Volume 25, Issue 5, pp. 744 - 750
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2016, Volume 34, Issue 15_suppl, pp. e23097 - e23097
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2017, Volume 35, Issue 15_suppl, pp. e13546 - e13546
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 11/2015, Volume 33, Issue 32, pp. 3817 - 3825
Journal Article
Journal Article