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Journal Article
Nature, ISSN 0028-0836, 2014, Volume 512, Issue 1, pp. 78 - 81
Myeloproliferative neoplasms (MPNs) are diseases caused by mutations in the haematopoietic stem cell (HSC) compartment. Most MPN patients have a common... 
TYROSINE KINASE JAK2 | JAK2-V617F | ACTIVATING MUTATION | POLYCYTHEMIA-VERA | BONE | MULTIDISCIPLINARY SCIENCES | Neuroprotective Agents - therapeutic use | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Sympathetic Nervous System - drug effects | Humans | Hematopoietic Stem Cells - pathology | Myeloproliferative Disorders - pathology | Sympathetic Nervous System - physiopathology | Adrenergic beta-3 Receptor Agonists - pharmacology | Neuroprotective Agents - pharmacology | Interleukin-1beta - metabolism | Neoplastic Stem Cells - pathology | Female | Sympathetic Nervous System - pathology | Schwann Cells - drug effects | Hematopoietic Stem Cells - drug effects | Nerve Fibers - pathology | Mesenchymal Stromal Cells - drug effects | Stem Cell Niche | Janus Kinase 2 - genetics | Nerve Fibers - drug effects | Schwann Cells - pathology | Myeloproliferative Disorders - drug therapy | Receptors, Adrenergic, beta-3 - metabolism | Disease Progression | Neoplasms - drug therapy | Nestin - metabolism | Adrenergic beta-3 Receptor Agonists - therapeutic use | Animals | Mice | Mesenchymal Stromal Cells - pathology | Neoplasms - pathology | Complications and side effects | Development and progression | Health aspects | Peripheral nerve diseases | Hematopoietic stem cells | Myeloproliferative disorders | Tumors | Studies | Mutation | Kinases | Rodents | Stem cells | Apoptosis
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 53, pp. 90614 - 90615
Journal Article
Cancer Research, ISSN 0008-5472, 12/2015, Volume 75, Issue 23, pp. 5106 - 5119
Journal Article
Cell Stem Cell, ISSN 1934-5909, 12/2014, Volume 15, Issue 6, pp. 791 - 804
Journal Article
Haematologica, ISSN 0390-6078, 09/2018, Volume 103, Issue 10, pp. 1593 - 1603
Pathological erythropoiesis with consequent anemia is a leading cause of symptomatic morbidity in internal medicine. The etiologies of anemia are complex and... 
POLYCYTHEMIA-VERA | STIMULATING AGENTS | INEFFECTIVE ERYTHROPOIESIS | FLOW-CYTOMETRY EVALUATION | STEM-CELL | ACUTE ERYTHROID LEUKEMIA | CHRONIC KIDNEY-DISEASE | ESSENTIAL THROMBOCYTHEMIA | HEMATOLOGY | DARBEPOETIN ALPHA | MYELODYSPLASTIC SYNDROMES | Life Sciences | Cancer | Review
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, p. e0152321
Chromosomal translocations involving the nucleoporin NUP98 have been described in several hematopoietic malignancies, in particular acute myeloid leukemia... 
TRANSLOCATION | CELLS | C-TERMINUS | GENE | PORE COMPLEX | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | NUCLEOPORIN NUP98 | NUP98-HOXA9 | LAP2-ALPHA | T(7/11)(P15,P15) | Translocation, Genetic | Oncogene Proteins, Fusion - metabolism | Mitosis | Homeodomain Proteins - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | DNA-Binding Proteins - analysis | Membrane Proteins - analysis | DNA-Binding Proteins - metabolism | Nuclear Pore Complex Proteins - genetics | Oncogene Proteins, Fusion - analysis | Membrane Proteins - metabolism | Nuclear Envelope - genetics | Leukemia, Myeloid, Acute - pathology | Nuclear Pore Complex Proteins - metabolism | Bone Marrow Cells - pathology | Nuclear Pore Complex Proteins - analysis | Homeodomain Proteins - genetics | Nuclear Envelope - metabolism | Phenotype | Animals | Cell Cycle | Homeodomain Proteins - analysis | Oncogene Proteins, Fusion - genetics | Mice | HeLa Cells | Nuclear Envelope - pathology | Bone Marrow Cells - metabolism | Leukemia, Myeloid, Acute - genetics | Translocation (Genetics) | Analysis | Leukemia | Causes of | Influence | Genetic aspects | Research | Gene expression | Transcription factors | Laboratories | Homeobox | Proteins | Alterations | Cell cycle | Bone marrow | Chimeras | Localization | Chromosomes | Immunoglobulins | Hematology | Myeloid leukemia | Cloning | Nuclear transport | Hemopoiesis | Medicine | Chromosome translocations | Microscopy | Immortalization | Stem cells | Leukemogenesis | Aberration | Molecular biology | Position (location) | Acute myeloid leukemia | Cancer
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2017, Volume 31, Issue 3, pp. 452 - 465
Journal Article
Cancer Research, ISSN 0008-5472, 02/2016, Volume 76, Issue 3 Supplement, pp. IA23 - IA23
Journal Article
Experimental Hematology, ISSN 0301-472X, 09/2017, Volume 53, pp. S112 - S113
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 2, pp. 161 - 163
gain-of-function mutations have been shown to cause myeloproliferative neoplasms. In this issue of , demonstrate that these JAK2 mutants, but not wild-type... 
PRMT5 | METHYLTRANSFERASE | ARGININE METHYLATION | ONCOLOGY | CELL BIOLOGY | Methylation
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 2012, Volume 30, Issue 4, pp. 1083 - 1096
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 09/2012, Volume 30, Issue 4, pp. 1083 - 1096