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EMBO reports, ISSN 1469-221X, 04/2019, Volume 20, Issue 4
Journal Article
EMBO reports, ISSN 1469-221X, 04/2019, Volume 20, Issue 4, p. n/a
Oncogene‐dependent cancers upregulate and use lysosomal biogenesis for nutrient supply. It is unclear which lysosomal proteins and functions are essential for... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Proteins | Calcium release channels | Cell proliferation | Cell growth | Pharmacology | Calcium ions | Tumors
Journal Article
Cell Calcium, ISSN 0143-4160, 06/2019, Volume 80, pp. 192 - 193
The Ca sensor STIM1 is essential for adaptive immune responses, yet patients with hypomorphic STIM1 mutations develop both immunodeficiency and autoimmunity,... 
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 01/2018, Volume 17, Issue 1, pp. 78 - 78
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 01/2016, Volume 68, Issue 1, pp. 31 - 34
Journal Article
Drugs, ISSN 0012-6667, 04/2017, Volume 77, Issue 5, pp. 521 - 546
The Janus kinase/signal transduction and activator of transcription (JAK-STAT) signaling pathway is implicated in the pathogenesis of inflammatory and... 
PHASE 2B TRIAL | VX-509 DECERNOTINIB | ALOPECIA-AREATA | MODIFYING ANTIRHEUMATIC DRUG | JANUS KINASE INHIBITOR | ACTIVE RHEUMATOID-ARTHRITIS | INADEQUATE RESPONSE | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TOFACITINIB CP-690,550 | DRUG-DRUG INTERACTIONS | Janus Kinases - genetics | Humans | STAT Transcription Factors - metabolism | Janus Kinases - metabolism | Janus Kinases - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Inflammation - metabolism | STAT Transcription Factors - genetics | Signal Transduction - drug effects | Inflammation - drug therapy | Protein Kinase Inhibitors - therapeutic use | Protein Kinase Inhibitors - pharmacology | STAT Transcription Factors - antagonists & inhibitors | Autoimmune Diseases - metabolism | Autoimmune Diseases - drug therapy | Regulatory agencies | Inflammatory bowel diseases | Phosphorylation | Transcription factors | Disease | Transcription | Pathogenesis | Genes | Disorders | Clinical trials | Intracellular signalling | Arthritis | Kinases | Inflammatory diseases | Signal transduction | Intestine | Rodents | Janus kinase | Tumor necrosis factor-TNF | Medical research | Cytokines | Psoriasis | Baldness | Immunodeficiency | Patients | Diseases | Reviews | Rheumatoid arthritis | Transduction | Intracellular | Mutation | Autoimmune diseases
Journal Article
Nature Reviews Rheumatology, ISSN 1759-4790, 01/2016, Volume 12, Issue 1, pp. 25 - 36
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 01/2016, Volume 68, Issue 1, pp. 31 - 34
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2015, Volume 48, Issue 1, pp. 67 - 73
Journal Article
Gastroenterology, ISSN 0016-5085, 12/2019, Volume 157, Issue 6, pp. 1660 - 1672.e2
Journal Article
Journal Article