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Journal of Immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 4/2012, Volume 188, Issue 7, pp. 3031 - 3041
Ly108 (CD352) is a member of the Signaling Lymphocyte Activation Molecule (SLAM) family of receptors that signals through SLAM-associated protein (SAP), an SH2... 
Journal Article
Immunity, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 770 - 781
Follicular B helper T (Tfh) cells support high affinity and long-term antibody responses. Here we found that within circulating CXCR5 CD4 T cells in humans and... 
Journal Article
Journal Article
IMMUNITY, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 770 - 781
Journal Article
Current Protocols in Immunology, ISSN 1934-3671, 02/2019, Volume 124, Issue 1, pp. e62 - e62
The ability to alter gene expression directly in T lymphocytes has provided a powerful tool for understanding T cell biology, signaling, and function.... 
CRISPR | gene knockout | Cas9 | retroviral vector | murine T cells
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 4/2017, Volume 198, Issue 7, pp. 2699 - 2711
Patients with mutations in ITK are susceptible to viral infections, particularly Epstein Barr Virus, suggesting that these patients have defective function of... 
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2009, Volume 206, Issue 3, pp. 561 - 576
Journal Article
Immunity, ISSN 1074-7613, 2010, Volume 32, Issue 2, pp. 253 - 265
CD4 T cells deficient in signaling lymphocyte activation molecule (SLAM)-associated protein (SAP) exhibit a selective impairment in adhesion to... 
MOLIMMUNO | RESTING NK CELLS | B-CELLS | SAP | FOLLICULAR-HELPER-CELLS | AUTOIMMUNITY | HUMORAL IMMUNITY | MOLECULAR DISSECTION | IMMUNOLOGY | RECEPTORS | CUTTING EDGE | FAMILY | Antigens, CD - immunology | Cell Proliferation | Intracellular Signaling Peptides and Proteins - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Cell Differentiation - genetics | Lymphocyte Activation - genetics | Signaling Lymphocytic Activation Molecule Family Member 1 | T-Lymphocytes - metabolism | Antigens, Ly - metabolism | B-Lymphocytes - pathology | T-Lymphocytes - pathology | Intracellular Signaling Peptides and Proteins - genetics | B-Lymphocytes - metabolism | Cell Adhesion - genetics | Interferon-gamma - secretion | Mice, Inbred C57BL | Cells, Cultured | Receptors, Cell Surface - metabolism | Germinal Center - pathology | Signaling Lymphocytic Activation Molecule Family | Receptors, Cell Surface - immunology | Mice, Knockout | Cell Adhesion - immunology | Cell Differentiation - immunology | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Antigens, Ly - immunology | Signaling Lymphocytic Activation Molecule Associated Protein | T-Lymphocytes - immunology | Mice | Interleukins - secretion | Receptors, Cell Surface - genetics | Dendritic cells | T cells | Integrins | Proteins | Antigens | Flow cytometry | Rodents | Ligands | Software | Immune system | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 2011, Volume 35, Issue 6, pp. 919 - 931
Journal Article
Immunity, ISSN 1074-7613, 06/2012, Volume 36, Issue 6, pp. 986 - 1002
Humans and mice deficient in the adaptor protein SAP ( ) have a major defect in humoral immunity, resulting from a lack of T cell help for B cells. The role of... 
SLAM FAMILY RECEPTORS | NATURAL-KILLER-CELLS | HUMORAL IMMUNITY | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | MOLECULE-ASSOCIATED PROTEIN | LINKED LYMPHOPROLIFERATIVE-DISEASE | PROTEIN-TYROSINE-PHOSPHATASE | GERMINAL-CENTER | GENE-PRODUCT | CUTTING EDGE | Phosphorylation | Germinal Center - immunology | Antigens, Ly - genetics | Inositol Polyphosphate 5-Phosphatases | CD4-Positive T-Lymphocytes - immunology | Intracellular Signaling Peptides and Proteins - deficiency | Lymphopoiesis - physiology | Phosphotyrosine - physiology | Antigens, Ly - physiology | Immunologic Deficiency Syndromes - immunology | Intracellular Signaling Peptides and Proteins - genetics | Mice, Inbred C57BL | Natural Killer T-Cells - cytology | Mice, Transgenic | Phosphoric Monoester Hydrolases - physiology | Amino Acid Motifs | Mice, Knockout | Animals | B-Lymphocytes - immunology | Signaling Lymphocytic Activation Molecule Associated Protein | Immunological Synapses - immunology | Immunologic Deficiency Syndromes - genetics | Mice | Protein Processing, Post-Translational | Intracellular Signaling Peptides and Proteins - physiology | Lymphocyte Cooperation - physiology | Computer software industry | T cells | Genetic disorders | Proteins | Confidence intervals | Biomedical research | Lymphocytes | Rodents | Viral infections | Immune system | Cell adhesion & migration | Index Medicus | Germinal centers | Lymphocytes B | SHP-1 protein | Cell adhesion | Immunity (humoral) | Immunological synapses | Lymphocytes T | Natural killer cells | Differentiation | adaptor proteins | SAP protein | CD4 antigen
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2014, Volume 15, Issue 1, pp. 88 - 97
Journal Article