Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (79) 79
life sciences & biomedicine (77) 77
sepsis (56) 56
humans (45) 45
general & internal medicine (35) 35
male (35) 35
critical care medicine (33) 33
female (32) 32
middle aged (25) 25
abridged index medicus (23) 23
immunology (23) 23
mortality (23) 23
aged (21) 21
biomarkers (20) 20
inflammation (20) 20
gene expression (19) 19
animals (17) 17
intensive care units (17) 17
research (17) 17
critical care and intensive care medicine (16) 16
intensive care unit (16) 16
pneumonia (16) 16
host response (15) 15
infections (15) 15
mice (14) 14
respiratory system (14) 14
prospective studies (13) 13
analysis (11) 11
biomarkers - blood (11) 11
cell biology (11) 11
critically ill (11) 11
infection (11) 11
sepsis - diagnosis (11) 11
adult (10) 10
biomarker (10) 10
cardiovascular system & cardiology (10) 10
care and treatment (10) 10
critical illness (10) 10
health aspects (10) 10
hematology (10) 10
intensive care (10) 10
patients (10) 10
risk factors (10) 10
sepsis - mortality (10) 10
cardiac & cardiovascular systems (9) 9
gene expression profiling (9) 9
medicine (9) 9
sepsis - blood (9) 9
blood (8) 8
immune response (8) 8
genomics (7) 7
sepsis - immunology (7) 7
studies (7) 7
complications and side effects (6) 6
genetic aspects (6) 6
genomes (6) 6
immune system (6) 6
infectious diseases (6) 6
intensive care units - statistics & numerical data (6) 6
pathogenesis (6) 6
pathogens (6) 6
research article (6) 6
research support, non-u.s. gov't (6) 6
sepsis - genetics (6) 6
sepsis - metabolism (6) 6
yes (6) 6
biological and medical sciences (5) 5
biomarkers - analysis (5) 5
clinical trials (5) 5
diagnosis (5) 5
genetics (5) 5
microbiology (5) 5
netherlands (5) 5
no (5) 5
proteins (5) 5
sepsis - complications (5) 5
transcriptome (5) 5
young adult (5) 5
acute respiratory distress syndrome (4) 4
antibiotics (4) 4
ards (4) 4
arrhythmias, cardiac - genetics (4) 4
bacterial infections (4) 4
bioinformatics (4) 4
cardiovascular (4) 4
case-control studies (4) 4
cells, cultured (4) 4
cohort studies (4) 4
community-acquired infections - diagnosis (4) 4
cytokines (4) 4
development and progression (4) 4
electrocardiography (4) 4
genes (4) 4
interleukin-6 - blood (4) 4
leukocytes (4) 4
lipopolysaccharides - pharmacology (4) 4
lungs (4) 4
medical research (4) 4
mutation (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text The immunopathology of sepsis and potential therapeutic targets
by van der Poll, Tom and van de Veerdonk, Frank L and Scicluna, Brendon P and Netea, Mihai G
Nature reviews. Immunology, ISSN 1474-1733, 07/2017, Volume 17, Issue 7, pp. 407 - 420
Life Sciences & Biomedicine | Immunology | Science & Technology | Sepsis - immunology | Epigenomics | Humans | Microbiota | Animals | Sepsis - pathology | Bacterial Infections - immunology | Bacterial Infections - pathology | Sepsis - metabolism | Transcription, Genetic | Bacterial Infections - microbiology | Sepsis - microbiology | Bacterial Infections - metabolism | Sepsis | Care and treatment | Inflammation | Immune response | Research | Biological markers | Pathogens | Pathogenesis | Homeostasis | Biomarkers | Infections | Defects | Immune system | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia
by Schuijt, Tim J and Lankelma, Jacqueline M and Scicluna, Brendon P and de Sousa e Melo, Felipe and Roelofs, Joris J T H and de Boer, J Daan and Hoogendijk, Arjan J and de Beer, Regina and de Vos, Alex and Belzer, Clara and de Vos, Willem M and van der Poll, Tom and Wiersinga, W Joost
Gut, ISSN 0017-5749, 04/2016, Volume 65, Issue 4, pp. 575 - 583
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Pneumonia, Pneumococcal - immunology | Sepsis - immunology | Pneumonia, Pneumococcal - microbiology | Mice, Inbred C57BL | Immunity, Mucosal | Transcriptome | Bacterial Load | Streptococcus pneumoniae - immunology | Feces - microbiology | Pneumonia, Pneumococcal - metabolism | Animals | Sepsis - metabolism | Interleukin-10 - metabolism | Anti-Bacterial Agents - pharmacology | Mice | Gastrointestinal Microbiome - immunology | Macrophages, Alveolar - metabolism | Macrophages, Alveolar - immunology | Sepsis - microbiology | Research | Microbiota (Symbiotic organisms) | Pneumonia, Pneumococcal | Health aspects | Risk factors | Immune system | Tumor necrosis factor-TNF | Pneumonia | Bacterial infections | Mortality | Index Medicus | Abridged Index Medicus | INTESTINAL MICROBIOLOGY | BACTERIAL PATHOGENESIS | Gut Microbiota | BACTERIAL INFECTION | IMMUNOLOGY | SEPSIS | 1506 | Microbiological Laboratory | Microbiologie | Microbiology | VLAG | Laboratorium voor Microbiologie
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsis
by Van Vught, Lonneke A. V and Klouwenberg, Peter M. C. Klein and Spitoni, Cristian and Scicluna, Brendon P and Wiewel, Maryse A and Horn, Janneke and Schultz, Marcus J and Nürnberg, Peter and Bonten, Marc J. M and Cremer, Olaf L and Van Der Poll, Tom and MARS Consortium
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 04/2016, Volume 315, Issue 14, pp. 1469 - 1479
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Prospective Studies | Genomics | Humans | Middle Aged | Cross Infection - mortality | Intensive Care Units - statistics & numerical data | Male | Sepsis - complications | Gene Expression Profiling | Cross Infection - immunology | Incidence | Netherlands | Female | Catheter-Related Infections - epidemiology | Length of Stay - statistics & numerical data | Cross Infection - epidemiology | Severity of Illness Index | Sepsis - immunology | Hospital Mortality | Risk Factors | Shock, Septic - complications | Shock, Septic - mortality | Sepsis - genetics | Sepsis - mortality | Survival Analysis | Organ Dysfunction Scores | Aged | APACHE | Clinical trials | Sepsis | Intensive care | Mortality
Journal Article
Details down arrow
4. Full Text Classification of patients with septic shock: Are we there yet?
by Wittebole, Xavier and Scicluna, Brendon P
Journal of critical care, ISSN 0883-9441, 10/2018, Volume 47, pp. 320 - 321
Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text the search for efficacious new therapies in sepsis needs to embrace heterogeneity
by Scicluna, Brendon P and Kenneth Baillie, J
American journal of respiratory and critical care medicine, ISSN 1073-449X, 04/2019, Volume 199, Issue 8, pp. 936 - 938
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Consortia | Intensive care | Respiratory distress syndrome | Mortality | Classification | Clinical trials | Sepsis | Trends | Gene expression | Signatures | Generalized linear models | Steroids | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
by Cheng, Shih-Chin and Scicluna, Brendon P and Arts, Rob J. W and Gresnigt, Mark S and Lachmandas, Ekta and Giamarellos-Bourboulis, Evangelos J and Kox, Matthijs and Manjeri, Ganesh R and Wagenaars, Jori A. L and Cremer, Olaf L and Leentjens, Jenneke and van der Meer, Anne J and van de Veerdonk, Frank L and Bonten, Marc J and Schultz, Marcus J and Willems, Peter H. G. M and Pickkers, Peter and Joosten, Leo A. B and van der Poll, Tom and Netea, Mihai G
Nature immunology, ISSN 1529-2908, 2016, Volume 17, Issue 4, pp. 406 - 413
Life Sciences & Biomedicine | Immunology | Science & Technology | Prospective Studies | Humans | Middle Aged | Transcriptome | Immunoblotting | Male | Monocytes - metabolism | Monocytes - immunology | Lipopolysaccharides - immunology | Antifungal Agents - therapeutic use | Leukocytes - immunology | Young Adult | Sepsis - drug therapy | Immune Tolerance - immunology | Sepsis - metabolism | Adenosine Triphosphate - metabolism | Candidiasis, Invasive - drug therapy | Endotoxemia - immunology | Adult | Aspergillosis - metabolism | Female | Macrophages - immunology | NAD - metabolism | Aspergillosis - drug therapy | Cytokines - immunology | Sepsis - immunology | Interferon-gamma - therapeutic use | Lactic Acid - metabolism | Oxidative Phosphorylation | Oxygen Consumption | Energy Metabolism - immunology | Escherichia coli Infections - metabolism | Candidiasis, Invasive - metabolism | Immunity, Innate - immunology | Macrophages - metabolism | Animals | Candidiasis, Invasive - immunology | Glycolysis | Escherichia coli Infections - immunology | Mice | Endotoxemia - metabolism | Leukocytes - metabolism | Aspergillosis - immunology | Complications and side effects | Energy metabolism | Immune response | Bioenergetics | Abnormalities | Sepsis | Regulation | Leukocytes | Properties | Health aspects | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission
by Scicluna, Brendon P and Klein Klouwenberg, Peter M. C and van Vught, Lonneke A and Wiewel, Maryse A and Ong, David S. Y and Zwinderman, Aeilko H and Franitza, Marek and Toliat, Mohammad R and Nürnberg, Peter and Hoogendijk, Arie J and Horn, Janneke and Cremer, Olaf L and Schultz, Marcus J and Bonten, Marc J and van der Poll, Tom
American journal of respiratory and critical care medicine, ISSN 1073-449X, 2015, Volume 192, Issue 7, pp. 826 - 835
Sepsis | Biomarker | Pneumonia | Microarray | Blood | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Calcitonin Gene-Related Peptide | Community-Acquired Infections - diagnosis | Calcitonin - blood | Intensive Care Units | Protein Precursors - blood | Tissue Array Analysis | Humans | Middle Aged | Male | Gene Expression Profiling | Biomarkers - blood | Proteins - genetics | Interleukin-6 - blood | Pneumonia - diagnosis | Apoptosis Regulatory Proteins - genetics | Female | Aged | Interleukin-8 - blood | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Turning a New Page in Sepsis Molecular Diagnostics Necessitates Context-Specific Biomarkers
by Scicluna, Brendon P and van der Poll, Tom
Critical care medicine, ISSN 0090-3493, 2017, Volume 45, Issue 4, pp. e457 - E457
Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Understanding Heterogeneity in Biologic Phenotypes of Acute Respiratory Distress Syndrome by Leukocyte Expression Profiles
by Bos, Lieuwe D J and Scicluna, Brendon P and Ong, David S Y and Cremer, Olaf and van der Poll, Tom and Schultz, Marcus J and MARS Consortium
American journal of respiratory and critical care medicine, ISSN 1073-449X, 07/2019, Volume 200, Issue 1, pp. 42 - 50
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Up-Regulation | Intensive Care Units | Humans | Middle Aged | Computational Biology | Oxidative Phosphorylation | Transcriptome | Male | Respiratory Distress Syndrome, Adult - classification | Gene Expression Profiling | Mitochondria - metabolism | RNA, Messenger - metabolism | Respiratory Distress Syndrome, Adult - metabolism | Sepsis - genetics | Phenotype | Respiratory Distress Syndrome, Adult - genetics | MAP Kinase Signaling System - genetics | Sepsis - metabolism | Inflammation - genetics | Female | Aged | Leukocytes - metabolism | Cohort Studies | Health sciences | Intensive care | Critical care | Infections | Gene expression | Kinases | Patients | Epidemiology | Primary care | Medicine | Proteins | Genotype & phenotype | Respiratory distress syndrome | Precision medicine | Biomarkers | Population | Sepsis | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text A pilot study of a novel molecular host response assay to diagnose infection in patients after high-risk gastro-intestinal surgery
by Verboom, Diana M and Koster-Brouwer, Maria E and Ruurda, Jelle P and van Hillegersberg, Richard and van Berge Henegouwen, Mark I and Gisbertz, Suzanne S and Scicluna, Brendon P and Bonten, Marc J.M and Cremer, Olaf L and on behalf of the MARS consortium and MARS Consortium and MARS consortium
Journal of critical care, ISSN 0883-9441, 12/2019, Volume 54, pp. 83 - 87
Infection | Diagnostics | Esophagectomy | Sepsis | Inflammation | SeptiCyte LAB | Intensive care unit | yes | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study
by Uhel, Fabrice and Peters-Sengers, Hessel and Falahi, Fahimeh and Scicluna, Brendon P and van Vught, Lonneke A and Bonten, Marc J and Cremer, Olaf L and Schultz, Marcus J and van der Poll, Tom and MARS Consortium and MARS consortium and the MARS consortium
Intensive care medicine, ISSN 0342-4642, 08/2020, Volume 46, Issue 8, pp. 1576 - 1589
Host response | Sepsis | Critical Care and Intensive Care Medicine | Acute kidney injury | Mortality | Intensive care unit | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Netherlands | Gene expression | Health aspects | Analysis | Creatinine | Kidneys | Pathogenesis | Inflammation | Leukocytes | Regression analysis | Blood | Intensive care units | Hospitals | Biomarkers | Evolution | Injuries | Integrity | Index Medicus | Original
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights