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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2015, Volume 112, Issue 10, pp. 3002 - 3007
Journal Article
Science, ISSN 0036-8075, 6/2010, Volume 328, Issue 5986, pp. 1694 - 1698
Journal Article
Nature Biotechnology, ISSN 1087-0156, 03/2016, Volume 34, Issue 3, pp. 328 - 333
The combination of Cas9, guide RNA and repair template DNA can induce precise gene editing and the correction of genetic diseases in adult mammals. However,... 
MESSENGER-RNA | GENE | CORRECTS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DNA | MOUSE MODEL | HOMOLOGY-DIRECTED REPAIR | MICE | CAS9 | MAMMALIAN-CELLS | NUCLEASES | Enzymes | Usage | Nucleotide sequence | Genetic engineering | Genetic aspects | Gene therapy | Methods | Ribonucleic acid--RNA | DNA repair | Genomics | Index Medicus
Journal Article
Nature Methods, ISSN 1548-7091, 06/2012, Volume 9, Issue 6, pp. 588 - 590
Journal Article
Journal Article
Nature Biotechnology, ISSN 1087-0156, 12/2015, Volume 33, Issue 12, pp. 1240 - 1241
Cpf1 is one of a growing number of class II CRISPR-Cas effectors that expand both our understanding of bacterial immunity and our genome-editing toolset. 
SYSTEM | IMMUNITY | ENDONUCLEASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | Bacteria | Genomics | Immune system
Journal Article
Journal Article
Nature communications, ISSN 2041-1723, 11/2018, Volume 9, Issue 1, pp. 4856 - 12
The development of robust, versatile and accurate toolsets is critical to facilitate therapeutic genome editing applications. Here we establish... 
CELLS | GENE | MULTIDISCIPLINARY SCIENCES | RNA-GUIDED ENDONUCLEASE | CRISPR-CAS9 | SYSTEMS | CAS9 | TARGETING RANGE | HEMATOPOIETIC STEM | NUCLEASES | Nucleotide sequence | Clonal deletion | Editing | Deletion | Genomes | Nuclease | Chimeras | Ribonucleic acid--RNA | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 49, pp. 12447 - 12452
Heterochromatin is a silenced chromatin region essential for maintaining genomic stability and driving developmental processes. The complicated structure and... 
Chromatin | Heterochromatin | Sedimentation | Sir | COMPLEX | DOMAIN | ACETYLATION | MULTIDISCIPLINARY SCIENCES | MODEL | chromatin | ESTABLISHMENT | sedimentation | NUCLEOSOME