The Lancet, ISSN 0140-6736, 05/2018, Volume 391, Issue 10135, pp. 2107 - 2115
Tranexamic acid can prevent death due to bleeding after trauma and post-partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma...
SPOT SIGN | MEDICINE, GENERAL & INTERNAL | CRASH-2 | SAFETY | GROWTH | HEMATOMA EXPANSION | TRAUMA PATIENTS | ACTIVATED FACTOR-VII | Antifibrinolytic Agents - therapeutic use | Acute Disease | Cerebral Hemorrhage - drug therapy | Double-Blind Method | Humans | Middle Aged | Male | Treatment Outcome | Tranexamic Acid - therapeutic use | Young Adult | Stroke - etiology | Aged, 80 and over | Adult | Female | Aged | Cerebral Hemorrhage - complications | Stroke - therapy | Clinical trials | Analysis | Coma | Heart | Drug delivery systems | Intravenous administration | Hemorrhage | Optimization | Bleeding | Infusion | Randomization | Motivation | Consent | Occupational health | Stroke | Medical imaging | Health | Regression analysis | Patients | Trauma | Acids | Workers | Medical prognosis | Technology assessment | Hematoma | Fatalities | Adults
SPOT SIGN | MEDICINE, GENERAL & INTERNAL | CRASH-2 | SAFETY | GROWTH | HEMATOMA EXPANSION | TRAUMA PATIENTS | ACTIVATED FACTOR-VII | Antifibrinolytic Agents - therapeutic use | Acute Disease | Cerebral Hemorrhage - drug therapy | Double-Blind Method | Humans | Middle Aged | Male | Treatment Outcome | Tranexamic Acid - therapeutic use | Young Adult | Stroke - etiology | Aged, 80 and over | Adult | Female | Aged | Cerebral Hemorrhage - complications | Stroke - therapy | Clinical trials | Analysis | Coma | Heart | Drug delivery systems | Intravenous administration | Hemorrhage | Optimization | Bleeding | Infusion | Randomization | Motivation | Consent | Occupational health | Stroke | Medical imaging | Health | Regression analysis | Patients | Trauma | Acids | Workers | Medical prognosis | Technology assessment | Hematoma | Fatalities | Adults
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P241 - P241
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P265 - P266
Journal Article
Stroke Research and Treatment, ISSN 2090-8105, 2015, Volume 2015, pp. 429053 - 8
Background. Dysphagia after stroke is common, associated independently with poor outcome, and has limited treatment options. Pharyngeal electrical stimulation...
Transcutaneous electrical nerve stimulation | Care and treatment | Research | Deglutition disorders | Health aspects | Studies | Ethics | Stroke | Ostomy | Hospitals | Consent | Dysphagia | Review
Transcutaneous electrical nerve stimulation | Care and treatment | Research | Deglutition disorders | Health aspects | Studies | Ethics | Stroke | Ostomy | Hospitals | Consent | Dysphagia | Review
Journal Article
Stroke, ISSN 0039-2499, 11/2015, Volume 46, Issue 11, pp. 3194 - 3201
Nitric oxide donors are candidate treatments for acute stroke, potentially through hemodynamic, reperfusion, and neuroprotectant effects, especially if given...
blood pressure | nitric oxide | cerebral hemorrhage | nitroglycerin | stroke | Single-Blind Method | Time-to-Treatment | Vasodilator Agents - therapeutic use | Humans | Middle Aged | Nitroglycerin - therapeutic use | Male | Treatment Outcome | Stroke - drug therapy | Administration, Cutaneous | Nitric Oxide Donors - administration & dosage | Nitroglycerin - administration & dosage | Aged, 80 and over | Female | Aged | Nitric Oxide Donors - therapeutic use | Vasodilator Agents - administration & dosage
blood pressure | nitric oxide | cerebral hemorrhage | nitroglycerin | stroke | Single-Blind Method | Time-to-Treatment | Vasodilator Agents - therapeutic use | Humans | Middle Aged | Nitroglycerin - therapeutic use | Male | Treatment Outcome | Stroke - drug therapy | Administration, Cutaneous | Nitric Oxide Donors - administration & dosage | Nitroglycerin - administration & dosage | Aged, 80 and over | Female | Aged | Nitric Oxide Donors - therapeutic use | Vasodilator Agents - administration & dosage
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P615 - P616
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, p. e0164608
Background Stroke is associated with the development of cognitive impairment and dementia. We assessed the effect of intensive blood pressure (BP) and/or lipid...
DEMENTIA | MULTIDISCIPLINARY SCIENCES | INFORMANT QUESTIONNAIRE | RECENT LACUNAR STROKE | CLASSIFICATION | RELIABILITY | RECURRENT STROKE | ACE-R | ISCHEMIC-STROKE | VALIDITY | IMPAIRMENT | Prospective Studies | Humans | Stroke - complications | Stroke Rehabilitation | Male | Cognition Disorders - prevention & control | Cognition Disorders - etiology | Lipids - blood | Female | Aged | Blood Pressure - drug effects | Hypolipidemic Agents - therapeutic use | Practice Guidelines as Topic | Stroke (Disease) | Complications and side effects | Analysis | Lipids | Blood pressure | Cognition disorders | Risk factors | Dementia | Hypertension | Lipoproteins (low density) | Neurosciences | Stroke | Pressure effects | Cognitive ability | Clinical trials | Cognition | Patients | Blood | Cholesterol | Prevention | Hospitals | Cognition & reasoning | Nitric oxide | Dementia disorders | Psychiatry | Geriatrics
DEMENTIA | MULTIDISCIPLINARY SCIENCES | INFORMANT QUESTIONNAIRE | RECENT LACUNAR STROKE | CLASSIFICATION | RELIABILITY | RECURRENT STROKE | ACE-R | ISCHEMIC-STROKE | VALIDITY | IMPAIRMENT | Prospective Studies | Humans | Stroke - complications | Stroke Rehabilitation | Male | Cognition Disorders - prevention & control | Cognition Disorders - etiology | Lipids - blood | Female | Aged | Blood Pressure - drug effects | Hypolipidemic Agents - therapeutic use | Practice Guidelines as Topic | Stroke (Disease) | Complications and side effects | Analysis | Lipids | Blood pressure | Cognition disorders | Risk factors | Dementia | Hypertension | Lipoproteins (low density) | Neurosciences | Stroke | Pressure effects | Cognitive ability | Clinical trials | Cognition | Patients | Blood | Cholesterol | Prevention | Hospitals | Cognition & reasoning | Nitric oxide | Dementia disorders | Psychiatry | Geriatrics
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9968, pp. 617 - 628
Summary Background High blood pressure is associated with poor outcome after stroke. Whether blood pressure should be lowered early after stroke, and whether...
Internal Medicine | MEDICINE, GENERAL & INTERNAL | TAIST | REDUCTION | ACUTE ISCHEMIC-STROKE | TRANSDERMAL GLYCERYL TRINITRATE | RELIABILITY | OUTCOMES | SCALE | STATISTICAL-ANALYSIS | Brain Ischemia - complications | Hypertension | Single-Blind Method | Cerebral Hemorrhage - drug therapy | Vasodilator Agents - therapeutic use | Humans | Middle Aged | Nitroglycerin - therapeutic use | Male | Treatment Outcome | Stroke - drug therapy | Antihypertensive Agents - therapeutic use | Recovery of Function | Stroke - etiology | Brain Ischemia - drug therapy | Aged, 80 and over | Female | Aged | Disease Management | Odds Ratio | Cerebral Hemorrhage - complications | Stroke (Disease) | Antihypertensive drugs | Blood pressure | Nitric oxide | Medical research | Analysis | Medicine, Experimental | Stroke patients | Studies | Stroke | Heart attacks | Dysphagia | Drug therapy | Patients
Internal Medicine | MEDICINE, GENERAL & INTERNAL | TAIST | REDUCTION | ACUTE ISCHEMIC-STROKE | TRANSDERMAL GLYCERYL TRINITRATE | RELIABILITY | OUTCOMES | SCALE | STATISTICAL-ANALYSIS | Brain Ischemia - complications | Hypertension | Single-Blind Method | Cerebral Hemorrhage - drug therapy | Vasodilator Agents - therapeutic use | Humans | Middle Aged | Nitroglycerin - therapeutic use | Male | Treatment Outcome | Stroke - drug therapy | Antihypertensive Agents - therapeutic use | Recovery of Function | Stroke - etiology | Brain Ischemia - drug therapy | Aged, 80 and over | Female | Aged | Disease Management | Odds Ratio | Cerebral Hemorrhage - complications | Stroke (Disease) | Antihypertensive drugs | Blood pressure | Nitric oxide | Medical research | Analysis | Medicine, Experimental | Stroke patients | Studies | Stroke | Heart attacks | Dysphagia | Drug therapy | Patients
Journal Article
Emergency Medicine Journal, ISSN 1472-0205, 10/2017, Volume 34, Issue 10, pp. e6 - e7
BackgroundStroke is a severe condition with high morbidity and mortality. Despite treatment effects in acute stroke being predominantly time dependent (e.g....
Hypertension | Stroke | Blood pressure | Ambulance services
Hypertension | Stroke | Blood pressure | Ambulance services
Journal Article
The Lancet, ISSN 0140-6736, 03/2018, Volume 391, Issue 10123, pp. 850 - 859
Intensive antiplatelet therapy with three agents might be more effective than guideline treatment for preventing recurrent events in patients with acute...
MEDICINE, GENERAL & INTERNAL | TICAGRELOR | EFFICACY | MINOR STROKE | NORMAL VOLUNTEERS | PREVENTION | ACUTE STROKE | ATTACK | RISK | Prevention | Heart | Aspirin | Stroke | Medical imaging | Ischemia | Nitric oxide | Technology assessment | Dipyridamole | Clopidogrel | Patients
MEDICINE, GENERAL & INTERNAL | TICAGRELOR | EFFICACY | MINOR STROKE | NORMAL VOLUNTEERS | PREVENTION | ACUTE STROKE | ATTACK | RISK | Prevention | Heart | Aspirin | Stroke | Medical imaging | Ischemia | Nitric oxide | Technology assessment | Dipyridamole | Clopidogrel | Patients
Journal Article
Clinical Science, ISSN 0143-5221, 07/2017, Volume 131, Issue 14, pp. 1561 - 1578
Vascular dementia (VaD) is the second commonest cause of dementia. Stroke is the leading cause of disability in adults in developed countries, the second major...
MEDICINE, RESEARCH & EXPERIMENTAL | SERUM TOTAL CHOLESTEROL | AMYLOID-BETA PEPTIDE | DENSITY-LIPOPROTEIN CHOLESTEROL | MODERATE ALZHEIMER-DISEASE | SMALL-VESSEL DISEASE | WHITE-MATTER HYPERINTENSITIES | APOLIPOPROTEIN-E GENOTYPE | CORONARY-HEART-DISEASE | LIPID-LOWERING AGENTS | IDEAL CARDIOVASCULAR HEALTH | Alzheimer Disease - etiology | Humans | Risk Factors | Hypercholesterolemia - drug therapy | Dementia, Vascular - prevention & control | Cerebral Hemorrhage - epidemiology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Dementia, Vascular - etiology | Dementia, Vascular - epidemiology | Hypercholesterolemia - complications | Hypolipidemic Agents - therapeutic use | Cerebral Hemorrhage - complications | Hypercholesterolemia - epidemiology
MEDICINE, RESEARCH & EXPERIMENTAL | SERUM TOTAL CHOLESTEROL | AMYLOID-BETA PEPTIDE | DENSITY-LIPOPROTEIN CHOLESTEROL | MODERATE ALZHEIMER-DISEASE | SMALL-VESSEL DISEASE | WHITE-MATTER HYPERINTENSITIES | APOLIPOPROTEIN-E GENOTYPE | CORONARY-HEART-DISEASE | LIPID-LOWERING AGENTS | IDEAL CARDIOVASCULAR HEALTH | Alzheimer Disease - etiology | Humans | Risk Factors | Hypercholesterolemia - drug therapy | Dementia, Vascular - prevention & control | Cerebral Hemorrhage - epidemiology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Dementia, Vascular - etiology | Dementia, Vascular - epidemiology | Hypercholesterolemia - complications | Hypolipidemic Agents - therapeutic use | Cerebral Hemorrhage - complications | Hypercholesterolemia - epidemiology
Journal Article
Trials, ISSN 1745-6215, 12/2017, Volume 18, Issue 1, pp. 607 - 3
Rationale: Aside from blood pressure lowering, treatment options for intracerebral haemorrhage remain limited and a proportion of patients will undergo early...
Tranexamic acid | Spontaneous intracerebral haemorrhage | Placebo-controlled | Randomised trial | Hyperacute | MEDICINE, RESEARCH & EXPERIMENTAL | Disability Evaluation | Antifibrinolytic Agents - therapeutic use | Cerebral Hemorrhage - drug therapy | Data Interpretation, Statistical | Prospective Studies | Double-Blind Method | Humans | Clinical Protocols | Logistic Models | Treatment Outcome | Antifibrinolytic Agents - adverse effects | Tranexamic Acid - therapeutic use | Tranexamic Acid - adverse effects | Cerebral Hemorrhage - diagnosis | Time Factors | Intention to Treat Analysis | Research Design | Mortality
Tranexamic acid | Spontaneous intracerebral haemorrhage | Placebo-controlled | Randomised trial | Hyperacute | MEDICINE, RESEARCH & EXPERIMENTAL | Disability Evaluation | Antifibrinolytic Agents - therapeutic use | Cerebral Hemorrhage - drug therapy | Data Interpretation, Statistical | Prospective Studies | Double-Blind Method | Humans | Clinical Protocols | Logistic Models | Treatment Outcome | Antifibrinolytic Agents - adverse effects | Tranexamic Acid - therapeutic use | Tranexamic Acid - adverse effects | Cerebral Hemorrhage - diagnosis | Time Factors | Intention to Treat Analysis | Research Design | Mortality
Journal Article
Journal of Stroke and Cerebrovascular Diseases, ISSN 1052-3057, 2016, Volume 26, Issue 4, pp. 894 - 894
Journal Article