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Cancer Letters, ISSN 0304-3835, 2016, Volume 381, Issue 1, pp. 49 - 57
Highlights • Seliciclib® augmented anticancer effects of Belinostat® in NSCLC cells • Increase in cellular apoptosis was observed with combined therapy •... 
Hematology, Oncology and Palliative Medicine | Caspase-8 activation | Seliciclib | Belinostat | Non-small cell lung cancer | Truncated BID | CARBOPLATIN | ROSCOVITINE | DEATH | DEPENDENT KINASE INHIBITOR | P53 | PACLITAXEL | Seliciclib (R) | ONCOLOGY | ENHANCEMENT | HISTONE DEACETYLASE INHIBITORS | EXPRESSION | Belinostat (R) | FLAVOPIRIDOL | Lung Neoplasms - drug therapy | Caspase Inhibitors - pharmacology | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Caspase 3 - metabolism | Caspase 8 - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Lung Neoplasms - pathology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Transfection | RNA Interference | Time Factors | Inhibitory Concentration 50 | Hydroxamic Acids - pharmacology | BH3 Interacting Domain Death Agonist Protein - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | A549 Cells | Carcinoma, Non-Small-Cell Lung - genetics | Purines - pharmacology | Carcinoma, Non-Small-Cell Lung - metabolism | Tumor Suppressor Protein p53 - metabolism | Sulfonamides - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Signal Transduction - drug effects | X-Linked Inhibitor of Apoptosis Protein - metabolism | Histone Deacetylase Inhibitors - pharmacology | BH3 Interacting Domain Death Agonist Protein - agonists | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Flow cytometry | Cell culture | Substance abuse treatment | Immunoglobulins | Cyclin-dependent kinases | Mortality | Lung cancer | Kinases | Gene expression | Experiments | Cancer therapies | Studies | Proteins | Cell cycle | Standard deviation | Drug dosages | Tumors | Apoptosis
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