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Science, ISSN 0036-8075, 9/2013, Volume 341, Issue 6152, pp. 1359 - 1365
Journal Article
Vaccine, ISSN 0264-410X, 08/2016, Volume 34, Issue 38, pp. 4618 - 4625
Regulatory T (Treg) cells have been shown in some cases to limit vaccine-specific immune responses and impact efficacy. Very little is known about the... 
Plasmodium falciparum | RTS,S | Heterologous prime-boost | Malaria vaccine | Circumsporozoite protein | Regulatory T cell | Medical research | Flow cytometry | Cell culture | Cytokines | Malaria | Infections | Vaccines | Military service | Studies | Lymphocytes | Research centers | Deoxyribonucleic acid--DNA | Volunteers
Journal Article
Journal Article
PLoS One, ISSN 1932-6203, 2013, Volume 8, Issue 2, p. e55571
BACKGROUND: Gene-based vaccination using prime/boost regimens protects animals and humans against malaria, inducing cell-mediated responses that in animal... 
APICAL MEMBRANE ANTIGEN-1 | SPOROZOITE INOCULATION | VIRUS ANKARA | IMMUNIZATION | NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | CIRCUMSPOROZOITE PROTEIN | DOUBLE-BLIND | NAIVE ADULTS | CYTOTOXIC T-LYMPHOCYTES | PHASE 2A TRIAL | Vaccines, DNA - genetics | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Humans | Middle Aged | Vaccines, DNA - immunology | Male | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Young Adult | Malaria Vaccines - adverse effects | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Adult | Female | Antigens, Protozoan - genetics | Malaria Vaccines - therapeutic use | Membrane Proteins - genetics | Adenoviruses, Human - immunology | Membrane Proteins - immunology | Vaccines, DNA - therapeutic use | Malaria, Falciparum - parasitology | Interferon-gamma - immunology | Vaccines, DNA - adverse effects | Adolescent | Malaria, Falciparum - immunology | Adenoviruses, Human - genetics | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Antigens | Wildlife conservation | Malaria | Liver | Vaccination | Malaria vaccine | Vaccines | T cells | Plasmodium falciparum | Advertising executives | Mosquitoes | Control | Analysis | Adenoviruses | DNA | Bites and stings | Genetic aspects | Health aspects | Enzyme-linked immunosorbent assay | Flow cytometry | Animal models | Goats | CD8 antigen | Antibodies | Leukocytes (mononuclear) | Lymphocytes T | Parasites | Aquatic insects | Immunity | Immunity (cell-mediated) | Replicating | Acquired immune deficiency syndrome--AIDS | Sporozoites | Peripheral blood mononuclear cells | Deoxyribonucleic acid--DNA | Circumsporozoite protein | Expression vectors | Vector-borne diseases | Medical research | Immunization | Statistical analysis | Diarrhea | Membrane proteins | Cytometry | Plasmids | γ-Interferon | Interferon | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS
Journal Article
Vaccine, ISSN 0264-410X, 08/2016, Volume 34, Issue 38, p. 4618
* Decrease in CD25.sup.hiFoxp3.sup.+ regulatory T cells with RTS,S vaccination. * Decrease in markers of regulation and exhaustion with RTS,S vaccination. *... 
Malaria | T cells | Malaria vaccine | Vaccination | Plasmodium falciparum | Antigens | Medical research | Medicine, Experimental
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e106241
Background: Fifteen volunteers were immunized with three doses of plasmid DNA encoding P. falciparum circumsporozoite protein (CSP) and apical membrane... 
APICAL MEMBRANE ANTIGEN-1 | RESPONSES | IMMUNOGENICITY | PROTEIN | PROTECTION | LIVER STAGES | SAFETY | MULTIDISCIPLINARY SCIENCES | VACCINE | CANDIDATE | CD8(+) T-CELLS | Antigens, Protozoan - immunology | DNA - immunology | Humans | Malaria, Falciparum - pathology | DNA - administration & dosage | Membrane Proteins - immunology | Plasmodium falciparum - immunology | Epitopes - immunology | Membrane Proteins - administration & dosage | Malaria, Falciparum - parasitology | Interleukin-2 - immunology | Malaria Vaccines - administration & dosage | Interferon-gamma - immunology | Antigens, Protozoan - administration & dosage | Malaria Vaccines - immunology | Malaria, Falciparum - immunology | Tumor Necrosis Factor-alpha - immunology | Plasmodium falciparum - pathogenicity | Adult | Immunologic Memory | Protozoan Proteins - administration & dosage | Adenoviridae - immunology | CD8-Positive T-Lymphocytes - immunology | Protozoan Proteins - immunology | Infection | Plasmodium falciparum | Immunization | Malaria | Adenoviruses | DNA | Interferon | T cells | Health aspects | Antigenic determinants | CD8 antigen | Liver | Effector cells | Lymphocytes T | Infections | Vaccines | Immunity | Proteins | Immunology | Interleukin 2 | Lymphocytes | Plasmid DNA | Volunteers | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Circumsporozoite protein | Vector-borne diseases | Antigens | Medical research | Immunological memory | Memory cells | Priming | Epitopes | Tumor necrosis factor-α | Vectors (Biology) | Membrane proteins | Plasmids | γ-Interferon | Comparative analysis | Deoxyribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, p. e0167175
Journal Article
Vaccine, ISSN 0264-410X, 08/2016, Volume 34, Issue 38, pp. 4618 - 4625
Journal Article
Pathogens and disease, ISSN 2049-632X, 06/2017, Volume 75, Issue 4
Background: Plasmid DNA encoding Plasmodium yoelii circumsporozoite protein (PyCSP) followed by boosting with recombinant vaccinia virus containing the PyCSP... 
protection | malaria | T cells | vaccines | mechanisms | INFECTIOUS DISEASES | BLOOD-STAGE | EXOERYTHROCYTIC ANTIGENS | NITRIC-OXIDE SYNTHASE | CIRCUMSPOROZOITE PROTEIN | GAMMA-INTERFERON | MICROBIOLOGY | IMMUNOLOGY | CD8(+) T-CELLS | SPOROZOITE VACCINE | PROTECTIVE IMMUNITY | MALARIA LIVER STAGES | STAGE MALARIA | Vaccines, DNA - genetics | Cell Survival | Coculture Techniques | Vaccines, Synthetic - genetics | Vaccines, DNA - immunology | Malaria - therapy | Plasmodium yoelii - immunology | Vaccines, Synthetic - immunology | Protozoan Proteins - genetics | Plasmodium yoelii - genetics | Vaccines, DNA - administration & dosage | Vaccinia virus - genetics | Drug Carriers | Hepatocytes - parasitology | Animals | Malaria Vaccines - administration & dosage | Malaria Vaccines - immunology | Mice | Vaccines, Synthetic - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Protozoan Proteins - immunology | Disease Models, Animal | Malaria Vaccines - genetics | Cell culture | CD8 antigen | Liver | Antibodies | Viruses | Lymphocytes T | Activation | DNA vaccines | Parasites | Vaccines | Immunity | Developmental stages | Rodents | Inhibition | Plasmid DNA | Deoxyribonucleic acid--DNA | Circumsporozoite protein | Recombinant | Immune system | Spleen | Vector-borne diseases | NF-κB protein | Immunization | Immune response | Malaria | Intercellular adhesion molecule 1 | Caspase | Cultures | Nitric-oxide synthase | Inhibitors | Hepatocytes | Nitric oxide | γ-Interferon | Interferon
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0131571
Journal Article