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Sexually Transmitted Infections, ISSN 1368-4973, 07/2019, Volume 95, Issue Suppl 1, p. A20
IntroductionGonorrhoea is becoming increasingly difficult to control due to antibiotic resistance and the absence of a vaccine. However, a vaccine to the... 
Proteins | Antigens | Immunoglobulins | Immunization | Gonorrhea | Females
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 12/2018
BackgroundNeisseria gonorrhoeae and Neisseria meningitidis are closely related bacteria that cause a significant global burden of disease. Control of... 
Journal Article
Sexually Transmitted Infections, ISSN 1368-4973, 07/2017, Volume 93, Issue Suppl 2, p. A30
Introduction Neisseria gonorrhoeae, the causative agent gonorrhoea, is a major public health problem worldwide with an estimated global incidence of 106... 
Antigens | Immunoglobulins | Infections | Vaccines | Gonorrhea
Journal Article
The Lancet, ISSN 0140-6736, 09/2017, Volume 390, Issue 10102, pp. 1567 - 1569
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/S0140-6736(17)31605-7 Byline: Kate L Seib (a) 
VACCINATION | MEDICINE, GENERAL & INTERNAL | Bacterial Vaccines | Humans | Gonorrhea | Vaccines | Antigens | Antibiotics | Infections | Drug resistance | Disease control | Public health | Index Medicus | Abridged Index Medicus
Journal Article
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 09/2019, Volume 69, Issue 7, p. 1101
Neisseria gonorrhoeae and Neisseria meningitidis are closely-related bacteria that cause a significant global burden of disease. Control of gonorrhoea is... 
Journal Article
Microbiology (Reading, England), ISSN 1350-0872, 04/2019, Volume 165, Issue 9, pp. 917 - 928
Phase-variable DNA methyltransferases control the expression of multiple genes via epigenetic mechanisms in a wide variety of bacterial species. These systems... 
Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2011, Volume 7, Issue 5, pp. e1002027 - e1002027
During infection Neisseria meningitidis (Nm) encounters multiple environments within the host, which makes rapid adaptation a crucial factor for meningococcal... 
HUMAN EPITHELIAL-CELLS | FACTOR-H-BINDING | MICROBIOLOGY | SEROGROUP-B MENINGOCOCCUS | GENOME | PATHOGENIC NEISSERIAE | VACCINE CANDIDATES | VIROLOGY | OUTER-MEMBRANE PROTEIN | GENE-EXPRESSION | STAPHYLOCOCCUS-AUREUS | SERINE-PROTEASE | PARASITOLOGY | Adaptation, Physiological | Sequence Deletion | Virulence Factors - genetics | Genes, Bacterial - genetics | Humans | Neisseria meningitidis, Serogroup B - physiology | Transcriptome | Male | Neisseria meningitidis, Serogroup B - genetics | Meningococcal Infections - microbiology | Antigens, Bacterial - genetics | Bacteremia - microbiology | Bacteremia - blood | RNA, Bacterial - genetics | Adult | Female | Neisseria meningitidis, Serogroup B - pathogenicity | Bacterial Proteins - genetics | Up-Regulation - genetics | Down-Regulation - genetics | Neisseria meningitidis, Serogroup B - growth & development | Genome, Bacterial - genetics | Gene Expression Regulation, Bacterial - genetics | Host-Pathogen Interactions - genetics | Models, Biological | Meningococcal Infections - blood | Cluster Analysis | Causes of | Sepsis | Neisseria meningitidis | Genetic aspects | Research | Health aspects | Microbiology | Pathogenesis | Mortality | Genomes | Gene expression | Blood | Proteins | Studies | Evolutionary biology | Mutagenesis | DNA methylation | Meningitis | Deoxyribonucleic acid--DNA | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 08/2019, p. fj201900669R
GNA2091 is one of the components of the 4-component meningococcal serogroup B vaccine (4CMenB) vaccine and is highly conserved in all meningococcal strains.... 
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1969, pp. 93 - 104
Fragment analysis (or fragment length analysis) is a PCR-based method which allows quantification of the size and proportion of a DNA repeat tract length of a... 
Phase-variable gene | DNA repeat sequence | Fragment analysis | Polymeric DNA tract | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 8, pp. 3770 - 3775
GNA2132 is a Neisseria meningitidis antigen of unknown function, discovered by reverse vaccinology, which has been shown to induce bactericidal antibodies in... 
Proteins | Antigens | Capsules | Glycosaminoglycans | Virulence factors | Vaccination | Antibodies | Neisseria meningitidis | Heparin | Immunity | Arg-rich region | Lactoferrin | Vaccine | NalP | Serum resistance | OUTER-MEMBRANE | COMPLEMENT | HUMAN-MILK LACTOFERRIN | MULTIDISCIPLINARY SCIENCES | SEROGROUP-B MENINGOCOCCUS | FACTOR-H | SERUM | IDENTIFICATION | serum resistance | vaccine | BACTERICIDAL ACTIVITY | SERINE-PROTEASE | Antimicrobial Cationic Peptides - immunology | Meningococcal Infections - immunology | Virulence Factors - genetics | Humans | Antigens, Bacterial - immunology | Blood Proteins - immunology | Virulence Factors - immunology | Antigens, Bacterial - genetics | Meningococcal Vaccines - chemistry | Neisseria meningitidis - immunology | Blood Proteins - genetics | Carrier Proteins - chemistry | Antimicrobial Cationic Peptides - genetics | Antibodies, Bacterial - blood | Carrier Proteins - immunology | Neisseria meningitidis - pathogenicity | Amino Acid Sequence | Antigens, Bacterial - chemistry | Meningococcal Vaccines - genetics | Antimicrobial Cationic Peptides - chemistry | Meningococcal Infections - prevention & control | Virulence Factors - chemistry | Blood Proteins - chemistry | Carrier Proteins - genetics | Lactoferrin - chemistry | Meningococcal Vaccines - immunology | Physiological aspects | Chemical properties | Research | Binding proteins | Health aspects | Bacteria | Correlation analysis | Binding sites | Index Medicus | meningococcal disease | Animal models | CAP37 protein | Proteinase | protective antigen | lactoferrin | Survival | Biological Sciences
Journal Article
PLoS Genetics, ISSN 1553-7390, 10/2009, Volume 5, Issue 10
  It can be argued that the arrival of the "genomics era" has significantly shifted the paradigm of vaccine and therapeutics development from microbiological... 
Studies | Candidates | Tuberculosis | Disease | Antibiotics | Pathogenesis | Lymphocytes | Genomics | Genetics | Staphylococcus infections | Genomes | Vaccines
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 11, pp. 4494 - 4499
Molecular data on a limited number of chromosomal loci have shown that the population of Neisseria meningitidis (Nm), a deadly human pathogen, is structured in... 
Biological taxonomies | DNA | Genes | Homologous recombination | Phylogenetics | Population structure | Evolution | Genomes | Neisseria meningitidis | Gene conversion | Population structure and dynamics | Pan-genome | Meningococcus | Phylogenetic clades | TRANSFORMATION | phylogenetic clades | MULTIDISCIPLINARY SCIENCES | pan-genome | population structure and dynamics | VIRULENCE | IDENTIFICATION | EVOLUTION | MICROBIAL PAN-GENOME | SEQUENCE | POPULATION-STRUCTURE | SELECTION | meningococcus | PATHOGENIC BACTERIA | Neisseria meningitidis - pathogenicity | Gene Conversion - genetics | Conserved Sequence - genetics | Genes, Bacterial - genetics | Species Specificity | Humans | Phylogeny | Operon - genetics | Mutagenesis, Insertional - genetics | DNA, Bacterial - genetics | Neisseria meningitidis - classification | Host-Pathogen Interactions - genetics | Recombination, Genetic | Base Sequence | DNA Restriction-Modification Enzymes - genetics | Neisseria meningitidis - genetics | Neisseria meningitidis - growth & development | Chromosome Inversion - genetics | Chromosome Segregation - genetics | Genetic aspects | Research | Genetic recombination | Population genetics | Gram-negative bacteria | Chromosomes | Deoxyribonucleic acid--DNA | Index Medicus | Pathogenicity | Pathogens | Commensals | homologous recombination | Virulence | Data processing | genomics | Biological Sciences
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 6512 - 9
Neisseria meningitidis is a Gram-negative bacterial pathogen that causes life threatening meningitis and septicemia. Neisseria Heparin Binding Antigen (NHBA)... 
PERFORMANCE LIQUID-CHROMATOGRAPHY | CELLS | ADHESION | PROTEOGLYCANS | INVASION | MULTIDISCIPLINARY SCIENCES | POLYSACCHARIDES | FACTOR-H | HEPARIN | MENINGOCOCCAL DISEASE | BRAIN | Heparan sulfate | Antigens | Phenotypes | Disaccharides | Septicemia | Vaccines | Membrane proteins | Proteins | Meningitis | Affinity | Chondroitin sulfate | Surface plasmon resonance | Heparin | Sulfate | Deoxyribonucleic acid--DNA
Journal Article