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The New England Journal of Medicine, ISSN 0028-4793, 07/2014, Volume 371, Issue 4, pp. 303 - 312
This study shows that the mTORC pathway is central to the antiphospholipid syndrome. Among patients with kidney transplants and antiphospholipid syndrome, 70%... 
RAPAMYCIN | BETA-GLYCOPROTEIN-I | MEDICINE, GENERAL & INTERNAL | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ANGIOPLASTY | ANTIBODY-MEDIATED REJECTION | POLYCYSTIC KIDNEY-DISEASE | SMOOTH-MUSCLE-CELLS | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | SYNDROME NEPHROPATHY | VASCULOPATHY | Endothelium, Vascular - cytology | Cell Proliferation | Kidney - blood supply | Kidney - pathology | TOR Serine-Threonine Kinases - metabolism | Humans | Immunoglobulin G | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Antiphospholipid Syndrome - complications | TOR Serine-Threonine Kinases - antagonists & inhibitors | Autopsy | Adult | Female | Antiphospholipid Syndrome - metabolism | Immunosuppressive Agents - pharmacology | Kidney Diseases - metabolism | Sirolimus - therapeutic use | Antiphospholipid Syndrome - drug therapy | Kidney Transplantation | Sirolimus - pharmacology | Antibodies, Antiphospholipid - metabolism | Analysis of Variance | Endothelium, Vascular - metabolism | Endothelium, Vascular - pathology | Kidney Diseases - etiology | Metabolic Networks and Pathways - drug effects | Care and treatment | Rapamycin | Health aspects | Antiphospholipid syndrome | TOR protein | Cell proliferation | Lupus | Heart attacks | Kidneys | Transplants & implants | Sirolimus | AKT protein | Antiphospholipid antibodies | Kinases | Thrombosis | Endothelial cells | Endothelium | 1-Phosphatidylinositol 3-kinase | Vascular diseases | Nephropathy | Biopsy | Autoimmune diseases | Kidney transplantation
Journal Article
Lancet Neurology, The, ISSN 1474-4422, 2014, Volume 13, Issue 2, pp. 150 - 158
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 4/2013, Volume 125, Issue 4, pp. 511 - 522
Journal Article
by Kovacs, Gabor G and Ferrer, Isidro and Grinberg, Lea T and Alafuzoff, Irina and Attems, Johannes and Budka, Herbert and Cairns, Nigel J and Crary, John F and Duyckaerts, Charles and Ghetti, Bernardino and Halliday, Glenda M and Ironside, James W and Love, Seth and Mackenzie, Ian R and Munoz, David G and Murray, Melissa E and Nelson, Peter T and Takahashi, Hitoshi and Trojanowski, John Q and Ansorge, Olaf and Arzberger, Thomas and Baborie, Atik and Beach, Thomas G and Bieniek, Kevin F and Bigio, Eileen H and Bodi, Istvan and Dugger, Brittany N and Feany, Mel and Gelpi, Ellen and Gentleman, Stephen M and Giaccone, Giorgio and Hatanpaa, Kimmo J and Heale, Richard and Hof, Patrick R and Hofer, Monika and Hortobágyi, Tibor and Jellinger, Kurt and Jicha, Gregory A and Ince, Paul and Kofler, Julia and Kövari, Enikö and Kril, Jillian J and Mann, David M and Matej, Radoslav and McKee, Ann C and McLean, Catriona and Milenkovic, Ivan and Montine, Thomas J and Murayama, Shigeo and Lee, Edward B and Rahimi, Jasmin and Rodriguez, Roberta D and Rozemüller, Annemieke and Schneider, Julie A and Schultz, Christian and Seeley, William and Seilhean, Danielle and Smith, Colin and Tagliavini, Fabrizio and Takao, Masaki and Thal, Dietmar Rudolf and Toledo, Jon B and Tolnay, Markus and Troncoso, Juan C and Vinters, Harry V and Weis, Serge and Wharton, Stephen B and White III, Charles L and Wisniewski, Thomas and Woulfe, John M and Yamada, Masahito and Dickson, Dennis W and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet
Acta Neuropathologica, ISSN 0001-6322, 1/2016, Volume 131, Issue 1, pp. 87 - 102
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2007, Volume 104, Issue 11, pp. 4694 - 4699
Journal Article
by Van Deerlin, Vivianna M and Sleiman, Patrick M. A and Martinez-Lage, Maria and Chen-Plotkin, Alice and Wang, Li-San and Graff-Radford, Neill R and Dickson, Dennis W and Rademakers, Rosa and Boeve, Bradley F and Grossman, Murray and Arnold, Steven E and Mann, David M. A and Pickering-Brown, Stuart M and Seelaar, Harro and Heutink, Peter and Van Swieten, John C and Murrell, Jill R and Ghetti, Bernardino and Spina, Salvatore and Grafman, Jordan and Hodges, John and Spillantini, Maria Grazia and Gilman, Sid and Lieberman, Andrew P and Kaye, Jeffrey A and Woltjer, Randall L and Bigio, Eileen H and Mesulam, Marsel and Al-Sarraj, Safa and Troakes, Claire and Rosenberg, Roger N and White, Charles L and Ferrer, Isidro and Lladó, Albert and Neumann, Manuela and Kretzschmar, Hans A and Hulette, Christine Marie and Welsh-Bohmer, Kathleen A and Miller, Bruce L and Alzualde, Ainhoa and De Munain, Adolfo Lopez and McKee, Ann C and Gearing, Marla and Levey, Allan I and Lah, James J and Hardy, John and Rohrer, Jonathan D and Lashley, Tammaryn and MacKenzie, Ian R. A and Feldman, Howard H and Hamilton, Ronald L and Dekosky, Steven T and Van Der Zee, Julie and Kumar-Singh, Samir and Van Broeckhoven, Christine and Mayeux, Richard and Vonsattel, Jean Paul G and Troncoso, Juan C and Kril, Jillian J and Kwok, John B. J and Halliday, Glenda M and Bird, Thomas D and Ince, Paul G and Shaw, Pamela J and Cairns, Nigel J and Morris, John C and McLean, Catriona Ann and Decarli, Charles and Ellis, William G and Freeman, Stefanie H and Frosch, Matthew P and Growdon, John H and Perl, Daniel P and Sano, Mary and Bennett, David A and Schneider, Julie A and Beach, Thomas G and Reiman, Eric M and Woodruff, Bryan K and Cummings, Jeffrey and Vinters, Harry V and Miller, Carol A and Chui, Helena C and Alafuzoff, Irina and Hartikainen, Päivi and Seilhean, Danielle and Galasko, Douglas and Masliah, Eliezer and Cotman, Carl W and Tũón, M Teresa and Martínez, M Cristina Caballero and Munoz, David G and Carroll, Steven L and Marson, Daniel and Riederer, Peter F and Bogdanovic, Nenad and Schellenberg, Gerard D and Hakonarson, Hakon and Trojanowski, John Q and Lee, Virginia M-Y and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 03/2010, Volume 42, Issue 3, pp. 234 - 239
Journal Article