X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (147) 147
humans (136) 136
oncology (102) 102
lung neoplasms - genetics (68) 68
female (53) 53
cell line, tumor (52) 52
male (50) 50
expression (45) 45
lung neoplasms - pathology (44) 44
lung cancer (42) 42
cancer (38) 38
mutation (37) 37
animals (34) 34
middle aged (29) 29
aged (28) 28
tumor cells, cultured (28) 28
dna methylation (27) 27
mice (27) 27
tumors (27) 27
gene (25) 25
biochemistry & molecular biology (24) 24
genetics & heredity (24) 24
carcinoma, non-small-cell lung - genetics (23) 23
carcinoma, small cell - genetics (23) 23
cell biology (23) 23
gene expression regulation, neoplastic (23) 23
genetic aspects (22) 22
mesothelioma - genetics (22) 22
mesothelioma - pathology (22) 22
apoptosis (21) 21
base sequence (21) 21
malignant mesothelioma (21) 21
gene expression (20) 20
mesothelioma (20) 20
adult (19) 19
molecular sequence data (19) 19
cells (18) 18
genes, tumor suppressor (18) 18
lung neoplasms - metabolism (18) 18
research (18) 18
analysis (17) 17
carcinoma, non-small-cell lung - pathology (17) 17
lung neoplasms - drug therapy (17) 17
respiratory system (17) 17
chromosome mapping (16) 16
polymerase chain reaction (16) 16
carcinoma (15) 15
genes (15) 15
mutations (15) 15
growth (14) 14
lung-cancer (14) 14
phosphorylation (14) 14
tumor-suppressor gene (14) 14
adenocarcinoma (13) 13
aged, 80 and over (13) 13
chemotherapy (13) 13
cpg islands (13) 13
lung cancer, non-small cell (13) 13
receptor, epidermal growth factor - genetics (13) 13
adenocarcinoma - genetics (12) 12
breast-cancer (12) 12
identification (12) 12
immunohistochemistry (12) 12
pleural mesothelioma (12) 12
proteins (12) 12
tumor suppressor genes (12) 12
cell proliferation (11) 11
chromosomes, human, pair 3 (11) 11
gene amplification (11) 11
homozygous deletion (11) 11
methylation (11) 11
prognosis (11) 11
promoter regions, genetic (11) 11
reverse transcriptase polymerase chain reaction (11) 11
yes-associated protein (11) 11
cell lines (10) 10
cell proliferation - drug effects (10) 10
chromosome deletion (10) 10
dna primers (10) 10
epidermal growth factor (10) 10
epigenesis, genetic (10) 10
health aspects (10) 10
mesothelioma - metabolism (10) 10
mice, nude (10) 10
pleural neoplasms - pathology (10) 10
polymorphism, genetic (10) 10
protein (10) 10
rna interference (10) 10
transcription factors - genetics (10) 10
tumor suppressor gene (10) 10
apoptosis - genetics (9) 9
article (9) 9
cell cycle (9) 9
deoxyribonucleic acid--dna (9) 9
dna mutational analysis (9) 9
dna-binding proteins - genetics (9) 9
gefitinib (9) 9
gene expression profiling (9) 9
hippo pathway (9) 9
mice, scid (9) 9
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Pathology International, ISSN 1320-5463, 06/2011, Volume 61, Issue 6, pp. 331 - 344
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2008, Volume 40, Issue 6, pp. 741 - 750
Epigenetic silencing in cancer cells is mediated by at least two distinct histone modifications, polycomb-based histone H3 lysine 27 trimethylation (H3K27triM)... 
CPG ISLAND MICROARRAY | HISTONE LYSINE METHYLATION | HYPERMETHYLATION | SUPPRESSOR GENE | CHROMATIN IMMUNOPRECIPITATION | COLORECTAL-CANCER | EMBRYONIC STEM-CELLS | PROSTATE-CANCER | GENETICS & HEREDITY | GROUP PROTEIN EZH2 | Prostatic Neoplasms - metabolism | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Phosphatidylinositol 3-Kinases - metabolism | RNA, Messenger - metabolism | Promoter Regions, Genetic - genetics | Prostate - metabolism | Breast Neoplasms - metabolism | DNA-Binding Proteins - metabolism | Prostate - pathology | DNA Methylation | Prostatic Neoplasms - genetics | Chromatin Immunoprecipitation | Microarray Analysis | Biomarkers, Tumor - metabolism | Female | Colony-Forming Units Assay | Microfilament Proteins - metabolism | Acetylation | Microfilament Proteins - genetics | Lung Neoplasms - genetics | Prostatic Neoplasms - pathology | DNA-Binding Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Cells, Cultured | Gene Silencing | Transcription Factors - antagonists & inhibitors | Alkaline Phosphatase - secretion | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Enhancer of Zeste Homolog 2 Protein | Phosphatidylinositol 3-Kinases - genetics | Transcription Factors - metabolism | Lysine - genetics | Polycomb Repressive Complex 2 | Breast Neoplasms - genetics | Histones - genetics | Breast Neoplasms - pathology | CpG Islands | Lysine - chemistry | Physiological aspects | Gene silencing | Genetic aspects | Research | Methylation | Cancer cells | Proteins | Genes | Genetics | Prostate cancer | Deoxyribonucleic acid--DNA | Cells | Apoptosis | Index Medicus
Journal Article
Cancer Science, ISSN 1347-9032, 04/2016, Volume 107, Issue 4, pp. 461 - 468
Mutant selective epidermal growth factor receptor‐tyrosine kinase inhibitors (EGFR‐TKIs), such as rociletinib and AZD9291, are effective for tumors with T790M... 
amplification | epidermal growth factor receptor‐tyrosine kinase inhibitors | T790M | Acquired resistance | MET | non‐small cell lung cancer | MET amplification | Non-small cell lung cancer | Epidermal growth factor receptor-tyrosine kinase inhibitors | non-small cell lung cancer | 1ST-LINE TREATMENT | GEFITINIB | MULTICENTER | ACTIVATION | T790M MUTATION | OPEN-LABEL | CHEMOTHERAPY | EGFR INHIBITORS | ONCOLOGY | epidermal growth factor receptor-tyrosine kinase inhibitors | AZD9291 | Lung Neoplasms - genetics | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Pyrimidines - administration & dosage | Humans | Lung Neoplasms - pathology | Proto-Oncogene Proteins c-met - genetics | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Acrylamides - administration & dosage | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Quinazolines - administration & dosage | Mutation | Oncogenes | Tyrosine | Phenols | Genetic aspects | Epidermal growth factor | Analysis | Phosphorylation | Epidermal growth factor receptors | Lung cancer | Adaptability | Drug resistance | Kinases | Cancer therapies | Patients | Chronic exposure | c-Met protein | Clonal deletion | MET protein | Gefitinib | Protein-tyrosine kinase | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | Original
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 385, pp. 215 - 224
Abstract Malignant mesothelioma (MM) frequently exhibits Hippo signaling pathway inactivation (HPI) mainly due to NF2 and/or LATS2 mutations, which leads to... 
Hematology, Oncology and Palliative Medicine | Cancer stem cell | YAP | Malignant mesothelioma | Hippo pathway | Statin | CD44 | PLEURAL MESOTHELIOMA | ORGAN SIZE CONTROL | CANCER STEM-CELLS | BREAST-CANCER | ZOLEDRONIC ACID | ONCOLOGY | SIGNALING PATHWAY | DEUBIQUITINASE BAP1 | TUMOR-SUPPRESSOR | CANDIDATE ONCOGENE | MEVALONATE PATHWAY | Lung Neoplasms - drug therapy | Neurofibromin 2 - genetics | Phosphorylation | Fatty Acids, Monounsaturated - pharmacology | Mesothelioma - pathology | Neoplastic Stem Cells - drug effects | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Phosphoproteins - metabolism | Simvastatin - pharmacology | Dose-Response Relationship, Drug | Fluvastatin | Transfection | Neoplastic Stem Cells - metabolism | RNA Interference | Time Factors | Tumor Suppressor Proteins - genetics | Hyaluronan Receptors - metabolism | Neoplastic Stem Cells - pathology | Ubiquitin Thiolesterase - metabolism | Indoles - pharmacology | Transcription, Genetic | Antineoplastic Agents - pharmacology | Binding Sites | Neurofibromin 2 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Lung Neoplasms - genetics | Promoter Regions, Genetic | Tumor Suppressor Proteins - metabolism | Neoplasm Invasiveness | Protein-Serine-Threonine Kinases - genetics | Mesothelioma - genetics | Phosphoproteins - genetics | Mevalonic Acid - metabolism | Ubiquitin Thiolesterase - genetics | Hyaluronan Receptors - genetics | Mesothelioma - drug therapy | Cell Movement - drug effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Mesothelioma - metabolism | Signal Transduction - drug effects | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Medical colleges | Mesothelioma | School construction | Statins | Stem cells | Medical research | Statistical analysis | Biosynthesis | Breast cancer | Metastasis | Gene expression | Experiments | Proteins | Insects | Medical prognosis | Cell cycle | Tumorigenesis | Tumors | Index Medicus
Journal Article
Journal Article
Environmental Health and Preventive Medicine, ISSN 1342-078X, 3/2008, Volume 13, Issue 2, pp. 65 - 70
Human malignancies develop via a multi-step that involves the accumulation of several key gene alterations with associated genetic and epigenetic events.... 
Malignant mesothelioma | Environmental Health | Asbestos | Medicine & Public Health | Oncogene | Health Promotion and Disease Prevention | Public Health/Gesundheitswesen | Molecular target therapy | Medicine/Public Health, general | Tumor suppressor gene | Studies | Molecular biology | Genes | Cancer | Tumors
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2008, Volume 3, Issue 4, pp. e2037 - e2037
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2017, Volume 19, Issue 8, pp. 996 - 1002
The Hippo pathway controls organ size and tissue homeostasis, with deregulation leading to cancer. The core Hippo components in mammals are composed of the... 
LOCALIZATION | HOMEOSTASIS | PHOSPHORYLATION | YAP/TAZ | YAP | STRESS | NLK | TAZ | CANCER | KINASES | CELL BIOLOGY | Osmotic Pressure | Phosphorylation | Cell Proliferation | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Transfection | Neoplasms - genetics | Time Factors | HEK293 Cells | Muscle Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Cytoplasm - enzymology | Signal Transduction | Neoplasms - enzymology | p38 Mitogen-Activated Protein Kinases - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Protein Transport | Muscle Proteins - genetics | Transcription Factors - metabolism | Animals | Mice, Nude | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Protein Binding | Adaptor Proteins, Signal Transducing - metabolism | Neoplasms - pathology | Smad protein | Deregulation | Transcription factors | Gene regulation | Serine | Homeostasis | Dephosphorylation | NF-AT protein | Kinases | Inactivation | Signal transduction | Localization | Deoxyribonucleic acid--DNA | Translocation | Transducers | Deactivation | Threonine | MAP kinase | Gene expression | Nuclear transport | Environmental stress | Yes-associated protein | Tea | Signaling | Cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 1, pp. E71 - E80
Journal Article
Journal Article
Redox Biology, ISSN 2213-2317, 09/2019, Volume 26, pp. 101297 - 101297
Hypoxia and acidity provide microenvironment for selection under evolutionary pressure and proliferation in cancer cells. Carbonic anhydrases (CAs) are a... 
Malignant mesothelioma | Iron metabolism | Catalytic Fe(II) | Carbonic anhydrase | Tumor biology | Ferroptosis | Apoptosis | Index Medicus
Journal Article