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Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 1776 - 1776
Journal Article
by Chaki, Moumita and Airik, Rannar and Ghosh, Amiya K and Giles, Rachel H and Chen, Rui and Slaats, Gisela G and Wang, Hui and Wang, Shaohui and Hurd, Toby W and Zhou, Weibin and Cluckey, Andrew and Gee, Heon Yung and Ramaswami, Gokul and Hong, Chen-Jei and Hamilton, Bruce A and Červenka, Igor and Ganji, Ranjani Sri and Bryja, Vitezslav and Arts, Heleen H and van Reeuwijk, Jeroen and Oud, Machteld M and Letteboer, Stef J.F and Roepman, Ronald and Husson, Hervé and Ibraghimov-Beskrovnaya, Oxana and Yasunaga, Takayuki and Walz, Gerd and Eley, Lorraine and Sayer, John A and Schermer, Bernhard and Liebau, Max C and Benzing, Thomas and Le Corre, Stephanie and Drummond, Iain and Janssen, Sabine and Allen, Susan J and Natarajan, Sivakumar and O’Toole, John F and Attanasio, Massimo and Saunier, Sophie and Antignac, Corinne and Koenekoop, Robert K and Ren, Huanan and Lopez, Irma and Nayir, Ahmet and Stoetzel, Corinne and Dollfus, Helene and Massoudi, Rustin and Gleeson, Joseph G and Andreoli, Sharon P and Doherty, Dan G and Lindstrad, Anna and Golzio, Christelle and Katsanis, Nicholas and Pape, Lars and Abboud, Emad B and Al-Rajhi, Ali A and Lewis, Richard A and Omran, Heymut and Lee, Eva Y.-H.P and Sekiguchi, JoAnn M and Saunders, Rudel and Johnson, Colin A and Garner, Elizabeth and Vanselow, Katja and Andersen, Jens S and Shlomai, Joseph and Nurnberg, Peter and Nurnberg, Gudrun and Levy, Shawn and Smogorzewska, Agata and Otto, Edgar A and Hildebrandt, Friedhelm
Cell, ISSN 0092-8674, 08/2012, Volume 150, Issue 3, pp. 533 - 548
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 02/2011, Volume 20, Issue 4, pp. 806 - 819
The Artemis gene encodes a DNA nuclease that plays important roles in non-homologous end-joining (NHEJ), a major double-strand break (DSB) repair pathway in... 
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 08/2009, Volume 16, Issue 8, pp. 808 - 813
The Mre11-Rad50-NBS1 (MRN) complex has many roles in response to DNA double-strand breaks, but its functions in repair by nonhomologous end joining (NHEJ)... 
HOOK DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | V(D)J RECOMBINATION | DOUBLE-STRAND BREAKS | HISTONE H2AX | CELL BIOLOGY | B-CELLS | REPAIR | GENOMIC STABILITY | BIOPHYSICS | LIGASE-III | HOMOLOGOUS RECOMBINATION | DNA-DAMAGE-RESPONSE | Cell Proliferation | DNA Repair Enzymes - genetics | Molecular Sequence Data | Male | Intracellular Signaling Peptides and Proteins - metabolism | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Flow Cytometry | ATP-Binding Cassette Transporters - genetics | Recombination, Genetic | Base Sequence | Tumor Suppressor Proteins - genetics | DNA Repair Enzymes - metabolism | ATP-Binding Cassette Transporters - metabolism | Cell Cycle Proteins - genetics | Female | Nuclear Proteins - genetics | Immunoglobulin Class Switching | Intracellular Signaling Peptides and Proteins - genetics | B-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | B-Lymphocytes - cytology | Tumor Suppressor Proteins - metabolism | Cell Cycle Proteins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | In Situ Hybridization, Fluorescence | Nuclear Proteins - metabolism | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Blotting, Western | Mice, Knockout | Animals | Histones - genetics | DNA Repair | Signal Transduction - physiology | Mice | Histones - metabolism | Mutation | Immunoglobulin Heavy Chains - genetics | Physiological aspects | Genetic aspects | B cells | Research | DNA repair | Molecular biology | Genetic recombination | Lymphocytes
Journal Article
Cancer Research, ISSN 0008-5472, 10/2017, Volume 77, Issue 19, pp. 5327 - 5338
Hypomorphic mutations in the genes encoding the MRE11/RAD50/NBS1 (MRN) DNA repair complex lead to cancer-prone syndromes. MRN binds DNA double-strand breaks,... 
GENOMIC STABILITY | ONCOLOGY | STRAND-BREAK REPAIR | END-JOINING PATHWAYS | TELANGIECTASIA-LIKE DISORDER | EMBRYONIC LETHALITY | ATM ACTIVATION | IONIZING-RADIATION | ATAXIA-TELANGIECTASIA | DNA-REPLICATION | PROTEIN COMPLEX | Genomic Instability | Cell Proliferation | Ataxia Telangiectasia Mutated Proteins - metabolism | Lymphoma, B-Cell - genetics | ATP-Binding Cassette Transporters - physiology | DNA Breaks, Double-Stranded | Embryo, Mammalian - metabolism | MRE11 Homologue Protein | Cell Transformation, Neoplastic - genetics | B-Lymphocytes - pathology | B-Lymphocytes - metabolism | Oncogenes | Fibroblasts - metabolism | DNA Repair Enzymes - physiology | DNA-Binding Proteins - physiology | Lymphoma, B-Cell - metabolism | Embryo, Mammalian - pathology | Cells, Cultured | DNA Replication | Fibroblasts - pathology | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Animals | DNA Repair | Lymphoma, B-Cell - pathology | Mice | Nuclear Proteins - physiology | Proto-Oncogene Proteins c-myc - genetics | Mutation | Cell Transformation, Neoplastic - pathology | Cell Cycle Proteins - physiology | Apoptosis | p53 Protein | DNA damage | c-Myc protein | Genomes | Myc protein | Mre11 nuclease | DNA repair | Genomic instability | Cell activation | MRE11 protein | Lymphocytes | Ataxia | Tumorigenesis | Nuclease | Repair | Deoxyribonucleic acid--DNA | Stability | Lymphoma | Immunological tolerance | Chromosome translocations | Lymphocytes B | Tumor suppressor genes | Replication | Ataxia telangiectasia | Cancer | B-cell lymphoma | Genome Stability | Cancer Therapy
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 06/2017, Volume 37, Issue 12
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2000, Volume 97, Issue 12, pp. 6630 - 6633
Journal Article
Journal Article
Cell, ISSN 0092-8674, 01/2006, Volume 124, Issue 2, pp. 260 - 262
A major pathway for repair of DNA double-strand breaks is nonhomologous end-joining (NHEJ). In this issue of , and report the discovery of a new NHEJ factor... 
V(D)J RECOMBINATION | INSTABILITY | MUTATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | DNA-Binding Proteins - physiology | Animals | DNA Damage | DNA Repair Enzymes | DNA Repair | Humans | DNA repair | DNA replication | Research | DNA
Journal Article