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Nature, ISSN 0028-0836, 06/2016, Volume 534, Issue 7607, pp. 396 - 401
Lymphoid organs, in which antigen presenting cells (APCs) are in close proximity to T cells, are the ideal microenvironment for efficient priming and... 
IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MACROPINOCYTOSIS | CYTOLYTIC T-LYMPHOCYTES | VACCINATION | ANTITUMOR IMMUNITY | INDUCTION | INTERFERONS | EFFICIENCY | ANTIGEN | Immunotherapy - methods | Dendritic Cells - immunology | Humans | Drug Carriers - administration & dosage | Antigens, Viral - genetics | Male | Interferon Type I - immunology | Autoantigens - genetics | Lymphoid Tissue - immunology | RNA - genetics | Cancer Vaccines - genetics | Lymphocyte Activation - immunology | Toll-Like Receptor 7 - immunology | Female | Membrane Glycoproteins - immunology | Dendritic Cells - metabolism | Macrophages - immunology | Disease Models, Animal | Antigens, Neoplasm - genetics | Antigens, Neoplasm - immunology | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Antigen Presentation - immunology | Static Electricity | Interferon Type I - secretion | Antigens, Viral - immunology | Lymphoid Tissue - cytology | Administration, Intravenous | Macrophages - metabolism | Animals | T-Lymphocytes - cytology | Melanoma - immunology | Autoantigens - immunology | T-Lymphocytes - immunology | Dendritic Cells - cytology | Mice | Nanoparticles - administration & dosage | RNA - administration & dosage | Melanoma - therapy | Clinical Trials, Phase I as Topic | Drugs | Molecular targeted therapy | Drug delivery systems | Care and treatment | Dendritic cells | Immunotherapy | Innovations | Genetic aspects | Health aspects | Methods | Cancer | Vehicles | Spleen | Antigens | Lymphatic system | Lungs | Lipids | Gene expression | Ribonucleic acid--RNA | Cancer therapies
Journal Article
Human Gene Therapy, ISSN 1043-0342, 12/2017, Volume 28, Issue 12, pp. 1138 - 1146
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2006, Volume 108, Issue 13, pp. 4009 - 4017
Journal Article
Journal Article
OncoImmunology, ISSN 2162-4011, 03/2019, Volume 8, Issue 3, p. 1553478
Cancer-associated mutations, mostly single nucleotide variations, can act as neoepitopes and prime targets for effective anti-cancer T-cell immunity. T cells... 
T cell cytotoxicity | T cell priming | T cells | Neoepitopes | CD8 | cancer immunotherapy | CTLA-4 BLOCKADE | RECOGNITION | PD-1 BLOCKADE | STABILITY | SENSITIVITY | RECEPTOR | IMMUNOLOGY | ONCOLOGY | IMMUNOTHERAPY | CD8(+) T cells | CD8(+) T cell cytotoxicity | IPILIMUMAB | CROSS-PRESENTATION | NEO-ANTIGENS
Journal Article
Cancer Research, ISSN 0008-5472, 10/2011, Volume 71, Issue 19, pp. 6132 - 6142
Intranodal immunization with antigen-encoding naked RNA may offer a simple and safe approach to induce antitumor immunity. RNA taken up by nodal dendritic... 
Journal Article
The Journal of Immunology, ISSN 0022-1767, 01/2008, Volume 180, Issue 1, pp. 309 - 318
Journal Article
The Journal of Immunology, ISSN 0022-1767, 09/2012, Volume 189, Issue 5, pp. 2682 - 2682
Journal Article
Cancer Research, ISSN 0008-5472, 11/2010, Volume 70, Issue 22, pp. 9031 - 9040
Although naked antigen-encoding RNA has entered clinical testing, basic knowledge on how to apply this promising novel vaccine format is still pending. By... 
Journal Article
OncoImmunology, 03/2019, Volume 8, Issue 3
Cancer-associated mutations, mostly single nucleotide variations, can act as neoepitopes and prime targets for effective anti-cancer T-cell immunity. T cells... 
T cell cytotoxicity | Neoepitopes | CD8 | cancer immunotherapy | T cell priming | T cells
Journal Article
Cancer Research, ISSN 0008-5472, 01/2011, Volume 71, Issue 2, pp. 516 - 527
Strategies for antibody-mediated cancer immunotherapy, such as active immunization with virus-like particle (VLP)-based vaccines, are gaining increasing... 
Journal Article
Cancer Research, ISSN 0008-5472, 03/2012, Volume 72, Issue 5, pp. 1081 - 1091
Multiple genetic events and subsequent clonal evolution drive carcinogenesis, making disease elimination with single-targeted drugs difficult. The multiplicity... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2008, Volume 180, Issue 1, pp. 309 - 318
Genetic modification of vaccines by linking the Ag to lysosomal or endosomal targeting signals has been used to route Ags into MHC class II processing... 
Journal Article
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