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Nature (London), ISSN 0028-0836, 2018, Volume 555, Issue 7697, pp. 469 - 474
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Central Nervous System Neoplasms - classification | Reproducibility of Results | Central Nervous System Neoplasms - genetics | Humans | Middle Aged | Child, Preschool | Infant | Male | Unsupervised Machine Learning | Young Adult | Central Nervous System Neoplasms - pathology | DNA Methylation | Adolescent | Aged, 80 and over | Adult | Female | Aged | Central Nervous System Neoplasms - diagnosis | Child | Cohort Studies | Genetic aspects | Nucleotide sequencing | Diagnosis | Methylation | Observations | Methods | DNA sequencing | Tumors | Cancer | Analysis | DNA | Machine learning | Central nervous system | Classifiers | Brain cancer | Standardization | Clinical trials | Probability | Data processing | Nervous system | Genomes | Gene expression | Generalized linear models | Learning algorithms | Classification | Diagnostic software | DNA methylation | Diagnostic systems | Bioinformatics | Deoxyribonucleic acid--DNA | Index Medicus
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ABCG2 impairs the activity of the aurora kinase inhibitor tozasertib but not of alisertib
BMC research notes, ISSN 1756-0500, 09/2015, Volume 8, Issue 1, pp. 484 - 484
Aurora kinase inhibitor | Alisertib | MLN8237 | VX680 | MK-0457 | Drug resistance | Tozasertib | ABCG2 | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Cell Survival - drug effects | Aurora Kinases - metabolism | Humans | Aurora Kinases - antagonists & inhibitors | Treatment Outcome | Pyrimidines - pharmacology | Neoplasm Proteins - metabolism | Piperazines - pharmacology | Azepines - pharmacology | ATP-Binding Cassette Transporters - metabolism | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Cell Death - drug effects | Medical research | Care and treatment | RNA | Medicine, Experimental | Drug therapy | Comparative analysis | Cancer | Index Medicus
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Acta neuropathologica, ISSN 0001-6322, 6/2016, Volume 131, Issue 6, pp. 903 - 910
Medicine & Public Health | Pathology | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Molecular Probe Techniques | Brain Neoplasms - diagnosis | Humans | Brain Neoplasms - genetics | Pathology, Molecular - methods | High-Throughput Nucleotide Sequencing - methods | Mutation - genetics | Genetic markers | Gliomas | Analysis | Brain tumors | Formaldehyde | Index Medicus
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Pediatric blood & cancer, ISSN 1545-5009, 03/2018, Volume 65, Issue 3, pp. e26893 - n/a
BRAF V600E inhibitor | vemurafenib | infant | desmoplastic infantile astrocytoma | low‐grade glioma | child | low-grade glioma | Pediatrics | Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Gene mutations | Gliomas | Chemotherapy | Inhibitors | Glioma | Addiction | Infants | Children | Astrocytoma | Index Medicus
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Journal of neuro-oncology, ISSN 0167-594X, 09/2020, Volume 149, Issue 3, pp. 499 - 510
Oncology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Pediatrics | Toxicity | Brain tumors | MEK inhibitors | MAP kinase | Kinases | Disease control | Recklinghausen's disease | Patients | Chemotherapy | Glioma | Protein kinase | Neurofibromatosis | Index Medicus | MAPK pathway | Pediatric low-grade glioma | Targeted therapy | NF1 | BRAF | MEK inhibitor | Clinical Study | Trametinib
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Neuro-oncology (Charlottesville, Va.), ISSN 1522-8517, 04/2019, Volume 21, Issue Supplement_2, pp. ii101 - ii101
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Neuro-oncology (Charlottesville, Va.), ISSN 1522-8517, 12/2017, Volume 19, Issue 12, pp. 1607 - 1617
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PloS one, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e108758 - e108758
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Proto-Oncogene Proteins c-mdm2 - genetics | Aurora Kinase B - metabolism | Apoptosis - drug effects | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Aurora Kinase A - antagonists & inhibitors | Aurora Kinase A - metabolism | Brain Neoplasms - metabolism | Tumor Suppressor Protein p53 - genetics | Antineoplastic Agents - pharmacology | Phosphorylation - drug effects | Proto-Oncogene Proteins c-mdm2 - metabolism | Aurora Kinase A - genetics | Aurora Kinase B - antagonists & inhibitors | Neuroblastoma - pathology | Aurora Kinase B - genetics | Signal Transduction | Neuroblastoma - genetics | Tumor Suppressor Protein p53 - metabolism | Brain Neoplasms - genetics | Imidazoles - pharmacology | Pyrimidines - pharmacology | Brain Neoplasms - drug therapy | Piperazines - pharmacology | Azepines - pharmacology | Drug Synergism | Histones - genetics | Cell Cycle Checkpoints - drug effects | Neuroblastoma - drug therapy | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Cell Proliferation - drug effects | Neuroblastoma - metabolism | Protein Kinase Inhibitors - pharmacology | Histones - metabolism | Primary Cell Culture | ATP Binding Cassette Transporter, Sub-Family B - genetics | Neuroblastoma | Tumor proteins | Phosphotransferases | Apoptosis | Phosphorylation | MDM2 protein | p53 Protein | Leukemia | Substrate inhibition | Aurora kinase | Breast cancer | Drug resistance | Kinases | Neuroblastoma cells | Signaling | Inhibitors | Cell lines | Cell cycle | Binding sites | Histone H3 | Index Medicus
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Molecular cancer therapeutics, ISSN 1535-7163, 05/2020, Volume 19, Issue 8, pp. 1736 - 1750
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Clinical cancer research, ISSN 1078-0432, 08/2016, Volume 22, Issue 16 Supplement, pp. A25 - A25
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Neuro-oncology (Charlottesville, Va.), ISSN 1522-8517, 08/2020
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Clinical cancer research, ISSN 1078-0432, 2019, Volume 25, Issue 6, pp. 1851 - 1866
Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Proliferation | Datasets as Topic | Prognosis | Humans | Brain Neoplasms - pathology | Male | Gene Expression Profiling | Brain Neoplasms - surgery | Astrocytoma - pathology | Animals | Cellular Senescence | Interleukin-1beta - metabolism | Progression-Free Survival | Female | Mice | Brain Neoplasms - mortality | Primary Cell Culture | Tumor Cells, Cultured | Child | Astrocytoma - mortality | Astrocytoma - surgery | Culture Media, Conditioned - metabolism | Disease Models, Animal | Index Medicus
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Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 7, pp. 11460 - 11479
KIAA1549:BRAF-fusion | Oncogene-induced senescence (OIS) | Pediatric low grade glioma | Pilocytic astrocytoma | MAPK-inhibitors | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Transduction, Genetic | Antigens, Polyomavirus Transforming - genetics | Humans | Cell Proliferation - physiology | Transcriptome | Cellular Senescence - physiology | Child, Preschool | Male | Gene Expression Profiling | Blotting, Western | Brain Neoplasms | Oncogene Proteins, Fusion - genetics | Proto-Oncogene Proteins B-raf - genetics | Polymerase Chain Reaction | Cell Line, Tumor | Cell Culture Techniques | Astrocytoma | Drug Screening Assays, Antitumor | Index Medicus
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