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1. Full Text Blockade of TNFα to Improve Human CD34+ Cell Repopulating Activity in Allogeneic Stem Cell Transplantation
by Senyuk, Vitalyi and Patel, Pritesh and Mahmud, Nadim and Rondelli, Damiano
Frontiers in immunology, ISSN 1664-3224, 2018, Volume 9, pp. 3186 - 3186
TNFα | GVHD | repopulating activity | T cells | CD34 | transplantation | Life Sciences & Biomedicine | Immunology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Cell Communication - immunology | Graft Survival - immunology | Humans | Transplantation, Heterologous | Gene Expression Profiling | Cell Self Renewal - drug effects | T-Lymphocytes - metabolism | Hematopoietic Stem Cell Transplantation - adverse effects | Models, Animal | Graft vs Host Disease - etiology | Immunosuppressive Agents - pharmacology | Hematopoietic Stem Cells - drug effects | Cytokines - metabolism | Animals, Genetically Modified | Hematopoietic Stem Cells - metabolism | Cell Communication - genetics | Animals | T-Lymphocytes - cytology | Cell Differentiation - drug effects | Hematopoietic Stem Cells - cytology | T-Lymphocytes - immunology | Mice | Hematopoietic Stem Cell Transplantation - methods | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus
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2. Full Text MiR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3
by Zhang, Yunyuan and Li, Liping and Yu, Chunjie and Senyuk, Vitalyi and Li, Fuxing and Quigley, John G and Zhu, Tongyu and Qian, Zhijian
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 6519 - 8
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Erythropoiesis | Catalase | Transcription | Myeloid leukemia | Stem cells | Superoxide dismutase | miRNA | Peroxidase | Acute myeloid leukemia | Progenitor cells | Hemopoiesis | FOXO3 protein
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3. Full Text Activation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cells
by Ming, Ming and Wang, Sheng and Wu, Wenshu and Senyuk, Vitalyi and Le Beau, Michelle M and Nucifora, Giuseppina and Qian, Zhijian
The Journal of biological chemistry, ISSN 0021-9258, 06/2012, Volume 287, Issue 27, pp. 22683 - 22690
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Cells, Cultured | Wnt Signaling Pathway - physiology | Mice, Transgenic | Hematopoietic Stem Cells - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | Hematopoietic Stem Cells - cytology | Bone Marrow Transplantation | Membrane Potential, Mitochondrial - physiology | Mice | Apoptosis - physiology | Mitochondria - physiology | Proto-Oncogene Proteins c-bcl-2 - genetics | Bone Marrow Cells - metabolism | Cell Survival - physiology | Index Medicus | Bcl-2 | Stem Cells | Signal Transduction | Hematopoiesis | Beta-Catenin | Wnt Pathway | Progenitor Cells
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4. Full Text Blockade of TNF[ALPHA] to Improve Human CD34+ Cell Repopulating Activity in Allogeneic Stem Cell Transplantation.(Tumor necrosis factor alpha)
by Senyuk, Vitalyi and Rondelli, Damiano and Mahmud, Nadim and Patel, Pritesh
Frontiers in immunology, ISSN 1664-3224, 01/2019
Usage | Transplantation | Research | Gene expression | Tumor necrosis factor | Stem cells
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5. Full Text Overcoming Melphalan Resistance By Targeting Crucial DNA Repair Pathways in Multiple Myeloma
by Patel, Pritesh Rajni and Senyuk, Vitalyi and Sweiss, Karen and Calip, Gregory and Oh, Annie and Mahmud, Nadim and Rondelli, Damiano
Biology of blood and marrow transplantation, ISSN 1083-8791, 03/2020, Volume 26, Issue 3, pp. S224 - S225
Enzymes | Medical research | Genes | Multiple myeloma | Transplantation | Gene expression | DNA repair | Analysis | DNA | Stem cells | Melphalan | Genetic research | Medicine, Experimental | Genetic aspects | Cancer
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6. Full Text Chromatin-modifying agent–expanded human cord blood cells display reduced allostimulatory capacity
by Petro, Benjamin and Mahmud, Dolores and Taioli, Simona and Ganapathy, Amudha and Senyuk, Vitalyi and Yoshinaga, Kazumi G and Suphangul, Montha and Rondelli, Damiano and Mahmud, Nadim
The Journal of immunology (1950), ISSN 0022-1767, 04/2019, Volume 202, Issue 8, pp. 2493 - 2501
Life Sciences & Biomedicine | Immunology | Science & Technology | Gene Expression Regulation - drug effects | Cell Differentiation - immunology | Fetal Blood - immunology | Hematopoietic Stem Cells - immunology | Cell Differentiation - drug effects | Gene Expression Regulation - immunology | Chromatin - immunology | Hematopoietic Stem Cells - cytology | Humans | Decitabine - pharmacology | Hydroxamic Acids - pharmacology | Antigens, Differentiation - immunology | Index Medicus | Abridged Index Medicus
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7. Full Text PARP Inhibition Synergizes with Melphalan but Does not Reverse Resistance Completely
by Patel, Pritesh R and Senyuk, Vitalyi and Sweiss, Karen and Calip, Greg S and Pan, Dipanjan and Rodriguez, Natalie and Oh, Annie and Mahmud, Nadim and Rondelli, Damiano
Biology of blood and marrow transplantation, ISSN 1083-8791, 07/2020, Volume 26, Issue 7, pp. 1273 - 1279
PARP1 | Myeloma | DNA repair | Alkylator | Melphalan | Transplantation | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Index Medicus
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8. Full Text PARP Inhibitor Veliparib and Busulfan in a Xenograft Model of Myeloproliferative Neoplasm
by Patel, Pritesh and Senyuk, Vitalyi and Rodriguez, Natalie S and Mahmud, Dolores and Oh, Annie Lee and Mahmud, Nadim and Barosi, Giovanni and Rondelli, Damiano
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3319 - 3319
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9. Full Text Repurposing Kir6/SUR2 Channel Activator Minoxidil to Arrests Growth of Gynecologic Cancers
by Fukushiro-Lopes, Daniela and Hegel, Alexandra D and Russo, Angela and Senyuk, Vitalyi and Liotta, Margaret and Beeson, Gyda C and Beeson, Craig C and Burdette, Joanna and Potkul, Ronald K and Gentile, Saverio
Frontiers in pharmacology, ISSN 1663-9812, 05/2020, Volume 11, pp. 577 - 577
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | cancer treatment | minoxidil | repurposing drug | mitochondria | ion channels | oxidative stress
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10. Full Text C75 Fatty Acid Synthesis (FAS) Inhibitor Has Potent Immunosuppressive Activity
by Senyuk, Vitalyi and Mahmud, Dolores and Oh, Annie L and Patel, Pritesh R and Rondelli, Damiano
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 2156 - 2156
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11. Full Text In-Vitro and in-Vivo Synergistic Effect of Melphalan and Dual DNA Repair Inhibition in Multiple Myeloma
by Patel, Pritesh R and Oh, Annie L and Senyuk, Vitalyi and Mahmud, Dolores and Mahmud, Nadim and Rondelli, Damiano
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 3301 - 3301
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12. Full Text Role of wnt/ß-catenin pathway in myeloid neoplasms with 5q deletion: A new therapeutic target
by Mittal, Nupur and Seba, Amber Dawn and Senyuk, Vitalyi and Qian, Zhijian
Journal of clinical oncology, ISSN 0732-183X, 05/2014, Volume 32, Issue 15_suppl, pp. 7076 - 7076
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13. Full Text Synergistic Cytotoxic Effect of Busulfan and the PARP Inhibitor Veliparib in Myeloproliferative Neoplasms
by Patel, Pritesh R and Senyuk, Vitalyi and Rodriguez, Natalie S and Oh, Annie L and Bonetti, Elisa and Mahmud, Dolores and Barosi, Gianni and Mahmud, Nadim and Rondelli, Damiano
Biology of blood and marrow transplantation, ISSN 1083-8791, 05/2019, Volume 25, Issue 5, pp. 855 - 860
Busulfan | Alkylator chemotherapy | PARP-1 | Veliparib | Myeloproliferative neoplasms | Transplantation | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Busulfan - pharmacology | Busulfan - therapeutic use | Humans | Myeloproliferative Disorders - drug therapy | Myeloproliferative Disorders - pathology | Neoplasms | Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Antineoplastic Agents, Alkylating - therapeutic use | Drug Synergism | Animals | Heterografts | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Benzimidazoles - pharmacology | Cell Proliferation - drug effects | Mice | Benzimidazoles - therapeutic use | Chemotherapy | Leukemia | Analysis | Hematopoietic stem cells | Sugars | Monosaccharides | Cancer | Index Medicus
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14. Full Text Inhibition of PARP and DNA-PK Lead to Synergistic Cytotoxicity with Melphalan in Multiple Myeloma
by Patel, Pritesh Rajni and Oh, Annie and Senyuk, Vitalyi and Mahmud, Dolores and Mahmud, Nadim and Rondelli, Damiano
Biology of blood and marrow transplantation, ISSN 1083-8791, 2016, Volume 23, Issue 3, pp. S269 - S269
Hematology, Oncology and Palliative Medicine | Genetic aspects | DNA | Multiple myeloma | Melphalan | Cancer
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15. Full Text Preclinical Study for the Use of Abatacept to Prevent Rejection of Allogeneic CD34+ Cells in a Xenograft Model
by Oh, Annie L and Mahmud, Dolores and Senyuk, Vitalyi and Bonetti, Elisa and Mahmud, Nadim and Patel, Pritesh R and Rondelli, Damiano
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 4271 - 4271
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16. Full Text Dual DNA Damage Repair Inhibition Synergizes with Alkylator Chemotherapy for Myeloma and Acute Leukemia
by Patel, Pritesh R and Senyuk, Vitalyi and Mahmud, Dolores and Oh, Annie L and Rondelli, Damiano
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 2053 - 2053
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17. Full Text The Cytotoxic Effect of the PARP Inhibitor ABT-888 on Myeloproliferative Neoplasms
by Patel, Pritesh R and Senyuk, Vitalyi and Bonetti, Elisa and Mahmud, Dolores and Kadkol, Shrihari S and Oh, Annie L and Mahmud, Nadim and Rondelli, Damiano
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 4276 - 4276
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18. Full Text EVI1 and hematopoietic disorders: History and perspectives
by Nucifora, Giuseppina and Laricchia-Robbio, Leopoldo and Senyuk, Vitalyi
Gene, ISSN 0378-1119, 2006, Volume 368, Issue 1-2, pp. 1 - 11
EVI1 (ecotropic viral integration site 1) | Murine myeloid leukemia | Human leukemia | Ecotropic retrovirus | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Amino Acid Sequence | Hematologic Diseases - pathology | DNA-Binding Proteins - physiology | Transcription Factors - physiology | History, 21st Century | Transcription Factors - history | Hematologic Diseases - metabolism | History, 20th Century | Humans | Molecular Sequence Data | Phylogeny | Sequence Homology, Amino Acid | Oncogene Proteins, Fusion | Animals | DNA-Binding Proteins - history | Mice | MDS1 and EVI1 Complex Locus Protein | Proto-Oncogenes - physiology | Leukemia | Analysis | Index Medicus
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19. Full Text The Cytotoxic Effect of the PARP Inhibitor ABT-888 on Myeloproliferative Neoplasms
by Patel, Pritesh Rajni and Senyuk, Vitalyi and Bonetti, Elisa and Mahmud, Dolores and Kadkol, Shrihari and Oh, Annie and Mahmud, Nadim and Rondelli, Damiano
Biology of blood and marrow transplantation, ISSN 1083-8791, 2016, Volume 23, Issue 3, pp. S251 - S252
Hematology, Oncology and Palliative Medicine | Tumors
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20. Full Text T Cell--Mediated Rejection of Human CD34.sup.+ Cells Is Prevented by Costimulatory Blockade in a Xenograft Model
by Oh, Annie L and Mahmud, Dolores and Nicolini, Benedetta and Mahmud, Nadim and Senyuk, Vitalyi and Patel, Pritesh R and Bonetti, Elisa and Arpinati, Mario and Ferrara, James L.M and Rondelli, Damiano
Biology of blood and marrow transplantation, ISSN 1083-8791, 12/2017, Volume 23, Issue 12, p. 2048
Analysis | Stem cells | Bone marrow | Transplantation | T cells
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