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Journal Article
American Journal of Physiology, ISSN 0363-6135, 04/2014, Volume 306, Issue 7, p. H1025
  Patients with heart failure (HF) have enhanced systemic IL-1 activity, and, in the experimental mouse model, IL-1 induces left ventricular (LV) systolic... 
Heart failure | Plasma | Cytokines | Rodents
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 49, pp. 19725 - 19730
Acute myocardial infarction (AMI) initiates an intense inflammatory response that promotes cardiac dysfunction, cell death, and ventricular remodeling. The... 
Heart | Myocardial infarction | Granulation tissue | Receptors | Ischemia | Cell death | Myocardium | Small interfering RNA | Renovations | Endothelial cells | NLRP3 | Interleukin-1 | Pyroptosis | NALP3 | EXTRACELLULAR ATP | CELLS | interleukin-1 | CASPASE-1 | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | RECEPTOR | pyroptosis | RESPONSES | DANGER SIGNALS | IN-VIVO | LIPOPOLYSACCHARIDE | Myocardial Infarction - genetics | Inflammasomes - metabolism | Apoptosis - drug effects | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Caspase 1 - metabolism | Male | Myocardial Infarction - diagnostic imaging | Receptors, Purinergic P2X7 - genetics | Ventricular Remodeling | RNA Interference | Cytoskeletal Proteins - metabolism | Pyridoxal Phosphate - analogs & derivatives | Disease Models, Animal | Cell Line | Gene Expression | Echocardiography | Pyridoxal Phosphate - pharmacology | Myocardial Infarction - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Inflammasomes - genetics | Carrier Proteins - genetics | Myocytes, Cardiac - pathology | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Myocytes, Cardiac - drug effects | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Fluorescent Antibody Technique | Lipopolysaccharides - pharmacology | Myocytes, Cardiac - metabolism | Receptors, Purinergic P2X7 - metabolism | Mice | Oligomers | Care and treatment | Heart cells | Physiological aspects | Development and progression | Health aspects | Heart attack | Biological Sciences
Journal Article
Plos One, ISSN 1932-6203, 2012, Volume 7, Issue 3, pp. e33438 - e33438
BACKGROUND: Heart failure (HF) is a complex clinical syndrome characterized by impaired cardiac function and poor exercise tolerance. Enhanced inflammation is... 
STATEMENT | CAPACITY | THERAPY | PERFORMANCE | MULTIDISCIPLINARY SCIENCES | ACUTE MYOCARDIAL-INFARCTION | MICE | ECHOCARDIOGRAPHY | ANAKINRA | BETA-ADRENERGIC RESPONSIVENESS | LEFT-VENTRICULAR FUNCTION | Humans | Middle Aged | Myocardial Contraction - physiology | Myocardial Contraction - drug effects | Male | Exercise Tolerance - drug effects | Exercise Test | C-Reactive Protein - metabolism | Adult | Female | Interleukin 1 Receptor Antagonist Protein - pharmacology | Cytokines - blood | Disease Models, Animal | Interleukin-1beta - antagonists & inhibitors | Interleukin-1beta - physiology | Heart Failure, Systolic - drug therapy | Inflammation Mediators - blood | Ventricular Dysfunction, Left - etiology | Biomarkers - blood | Mice, Inbred ICR | Recombinant Proteins - administration & dosage | Ventricular Dysfunction, Left - physiopathology | Animals | Interleukin-1beta - administration & dosage | Ventricular Dysfunction, Left - drug therapy | Oxygen Consumption - drug effects | Exercise Tolerance - physiology | Heart Failure, Systolic - physiopathology | Mice | Heart failure | Heart | Development and progression | Inflammation | Interleukins | Heart attacks | Working groups | Interleukin | Isoproterenol | Epidemiology | Beta blockers | Reduction | Efficiency | Interleukin 1 | Pretreatment | Drug therapy | Cardiology | Heart diseases | Drug dosages | Physical therapy | Medical research | Task forces | Cytokines | Medicare | Internal medicine | Interleukin 1 receptor antagonist | Oxygen consumption | Pharmacology | Interdisciplinary aspects | Patients | Disease prevention | Intolerance | Signaling | Physical fitness | Exercise physiology | Councils | Pharmacy | Flow velocity | Rehabilitation | Ventricle
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 55, Issue 10, pp. A20.E192 - A20.E192
Journal Article
American Journal of Physiology : Heart and Circulatory Physiology, ISSN 0363-6135, 2014, Volume 306, Issue 7, pp. H1025 - 31
Patients with heart failure (HF) have enhanced systemic IL-1 activity, and, in the experimental mouse model, IL-1 induces left ventricular (LV) systolic... 
Heart failure | Inflammation | Interleukins | Systolic dysfunction | heart failure | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | CARDIOVASCULAR EVENTS | INCREASED CIRCULATING INTERLEUKIN-18 | MONONUCLEAR-CELLS | BINDING-PROTEIN | systolic dysfunction | NECROSIS-FACTOR-ALPHA | RECEPTOR ANTAGONIST | interleukins | inflammation | ACUTE MYOCARDIAL-INFARCTION | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | BLOCKING INTERLEUKIN-1 | CONGESTIVE-HEART-FAILURE | Humans | Heart Failure - physiopathology | Male | Systole | Heart Failure - blood | Ventricular Dysfunction, Left - chemically induced | Time Factors | Ventricular Dysfunction, Left - blood | Ventricular Dysfunction, Left - genetics | Interleukin-6 - blood | Interleukin 1 Receptor Antagonist Protein - pharmacology | Disease Models, Animal | Signal Transduction | Mice, Inbred C57BL | Ventricular Function, Left - drug effects | Interleukin-18 - deficiency | Heart Failure - genetics | Heart Failure - metabolism | Interleukin-1beta | Ventricular Dysfunction, Left - physiopathology | Mice, Knockout | Antibodies - pharmacology | Ventricular Dysfunction, Left - metabolism | Animals | Intercellular Signaling Peptides and Proteins - pharmacology | Mice | Interleukin-18 - genetics | Heart Failure - chemically induced | Interleukin-18 - metabolism | Cardiac patients | Physiological aspects | Research | Cardiovascular research | Health aspects | Protein-protein interactions | Signaling and Stress Response
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A10342 - A10342
IntroductionThe prognostic impact of myocardial contraction fraction (MCF), in patients with severe aortic stenosis (AS) remains unexplored. We investigated... 
Care and treatment | Aortic valve stenosis | Patient outcomes | Heart valve replacement | Development and progression | Comparative analysis | Muscle contraction
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2010, Volume 55, Issue 10, p. A110.E1031
Journal Article
Cytokine, ISSN 1043-4666, 10/2010, Volume 52, Issue 1-2, pp. 19 - 19
Journal Article
Cytokine, ISSN 1043-4666, 10/2010, Volume 52, Issue 1-2, p. 88
Department of Medicine, University of Colorado Denver, Aurora, CO, USA 
Computer entertainment systems | Alpha 1-antitrypsin | Heart attack
Journal Article
Cytokine, ISSN 1043-4666, 10/2010, Volume 52, Issue 1-2, pp. 88 - 88
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2010, Volume 55, Issue 10, p. A20.E193
Journal Article
Catheterization and Cardiovascular Interventions, ISSN 1522-1946, 07/2017, Volume 90, Issue 1, pp. 104 - 111
Journal Article
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