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life sciences & biomedicine (26) 26
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1. Full Text Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
by Seshacharyulu, Parthasarathy and Pandey, Poomy and Datta, Kaustubh and Batra, Surinder K
Cancer letters, ISSN 0304-3835, 2013, Volume 335, Issue 1, pp. 9 - 18
Hematology, Oncology and Palliative Medicine | Protein phosphatase type 2A (PP2A) | Signaling | Phosphorylation | PP2A subunits | Dephosphorylation | Holoenzyme | Life Sciences & Biomedicine | Oncology | Science & Technology | Amino Acid Sequence | Protein Phosphatase 2 - chemistry | Isoenzymes - genetics | Humans | Gene Expression Regulation, Neoplastic | Protein Phosphatase 2 - genetics | Neoplasms - enzymology | Isoenzymes - chemistry | Cell Transformation, Neoplastic - metabolism | Protein Subunits - metabolism | Gene Expression Regulation, Enzymologic | Animals | Isoenzymes - metabolism | Protein Phosphatase 2 - metabolism | Conserved Sequence | Protein Processing, Post-Translational | Protein Subunits - chemistry | Protein Subunits - genetics | Index Medicus
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2. Full Text Easi-CRISPR: A robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins
by Quadros, Rolen M and Miura, Hiromi and Harms, Donald W and Akatsuka, Hisako and Sato, Takehito and Aida, Tomomi and Redder, Ronald and Richardson, Guy P and Inagaki, Yutaka and Sakai, Daisuke and Buckley, Shannon M and Seshacharyulu, Parthasarathy and Batra, Surinder K and Behlke, Mark A and Zeiner, Sarah A and Jacobi, Ashley M and Izu, Yayoi and Thoreson, Wallace B and Urness, Lisa D and Mansour, Suzanne L and Ohtsuka, Masato and Gurumurthy, Channabasavaiah B
Genome Biology, ISSN 1474-7596, 05/2017, Volume 18, Issue 1, pp. 92 - 92
Easi-CRISPR | Homology directed repair | CRISPR/Cas9 | Long ssDNA donors | Reporter and recombinase knock-in | Conditional knockout | CRISPR ribonucleoproteins | Cre-LoxP | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Endonucleases - genetics | Recombinational DNA Repair | Mutagenesis, Insertional - methods | Microinjections | RNA, Guide - genetics | RNA, Guide - metabolism | DNA, Single-Stranded - metabolism | Zygote - metabolism | Mice, Transgenic - genetics | Ribonucleoproteins - metabolism | Endonucleases - metabolism | Genetic Loci | Mice, Transgenic - growth & development | DNA, Single-Stranded - genetics | Founder Effect | Animals | Clustered Regularly Interspaced Short Palindromic Repeats | Integrases - metabolism | Ribonucleoproteins - genetics | Gene Editing - methods | Mice | Zygote - growth & development | Integrases - genetics | Genes, Reporter | Animal models | Transcription factors | Transcription | Single-stranded DNA | Genes | Homologous recombination | Embryo cells | Insertion | Stem cell transplantation | Genomes | DNA repair | Consortia | Custom design | Efficiency | Rodents | Cell cycle | Trends | Deoxyribonucleic acid--DNA | CRISPR | Transgenic mice | Ribonucleoproteins | Progeny | Zygotes | Alleles | Stem cells | Index Medicus | long ssDNA donors
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3. Full Text Targeting the EGFR signaling pathway in cancer therapy
by Seshacharyulu, Parthasarathy and Ponnusamy, Moorthy P and Haridas, Dhanya and Jain, Maneesh and Ganti, Apar K and Batra, Surinder K
Expert opinion on therapeutic targets, ISSN 1472-8222, 01/2012, Volume 16, Issue 1, pp. 15 - 31
EGFR mutations | signaling | anti-EGFR therapy | cancer | EGFR inhibitors | therapeutic targets | EGFR | Signaling | Anti-EGFR therapy | Cancer | Therapeutic targets | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Animals | Signal Transduction - drug effects | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Neoplasms - drug therapy | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
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4. MicroRNAs (miRNAs) as biomarker(s) for prognosis and diagnosis of gastrointestinal (GI) cancers
by Macha, Muzafar A and Seshacharyulu, Parthasarathy and Krishn, Shiv Ram and Pai, Priya and Rachagani, Satyanarayana and Jain, Maneesh and Batra, Surinder K
Current pharmaceutical design, ISSN 1381-6128, 2014, Volume 20, Issue 33, pp. 5287 - 5297
Gastrointestinal cancers | Prognosis | Diagnosis | miRNAs | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Gastrointestinal Neoplasms - genetics | Humans | Biomarkers, Tumor - metabolism | MicroRNAs - metabolism | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - metabolism
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5. Full Text MUC16 regulates TSPYL5 for lung cancer cell growth and chemoresistance by suppressing p53
by Lakshmanan, Imayavaramban and Salfity, Shereen and Seshacharyulu, Parthasarathy and Rachagani, Satyanarayana and Thomas, Abigail and Das, Srustidhar and Majhi, Prabin D and Nimmakayala, Rama Krishna and Vengoji, Raghupathy and Lele, Subodh M and Ponnusamy, Moorthy P and Batra, Surinder K and Ganti, Apar Kishor
Clinical cancer research, ISSN 1078-0432, 07/2017, Volume 23, Issue 14, pp. 3906 - 3917
Life Sciences & Biomedicine | Oncology | Science & Technology | Lung Neoplasms - genetics | A549 Cells | Lung Neoplasms - drug therapy | Cell Proliferation - genetics | CA-125 Antigen - genetics | Membrane Proteins - genetics | Deoxycytidine - administration & dosage | Humans | Gene Expression Regulation, Neoplastic | Janus Kinase 2 - genetics | Lung Neoplasms - pathology | Tumor Suppressor Protein p53 - genetics | Cisplatin - administration & dosage | Drug Resistance, Neoplasm - genetics | Animals | Mice | Nuclear Proteins - genetics | Deoxycytidine - analogs & derivatives | STAT3 Transcription Factor - genetics | Cell Movement | Disease Models, Animal | Gemcitabine | Growth rate | Glucocorticoids | Pathogenesis | p53 Protein | Lung cancer | Stat3 protein | Chemoresistance | Tumor cell lines | Tissues | Gene expression | Cell surface | Cisplatin | Metastases | Proteins | Signaling | Mucin | Experimental design | Janus kinase 2 | Biomarkers | Tumorigenesis | Genetic engineering | Cell migration | Cancer | Index Medicus | chemoresistance and Glucocorticoid receptor | lung cancer mouse model | MUC16 | TSPYL5 | p53
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6. Full Text MUC16: molecular analysis and its functional implications in benign and malignant conditions
by Haridas, Dhanya and Ponnusamy, Moorthy P and Chugh, Seema and Lakshmanan, Imayavaramban and Seshacharyulu, Parthasarathy and Batra, Surinder K
The FASEB journal, ISSN 0892-6638, 10/2014, Volume 28, Issue 10, pp. 4183 - 4199
domain structure | cancer | MUC16 | animal model | Animal model | Domain structure | Cancer | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Animals | Epithelial Cells - metabolism | CA-125 Antigen - genetics | Membrane Proteins - genetics | Humans | Membrane Proteins - metabolism | Neoplasms - diagnosis | CA-125 Antigen - metabolism | Index Medicus
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7. Full Text Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer
by Rachagani, Satyanarayana and Macha, Muzafar A and Heimann, Nicholas and Seshacharyulu, Parthasarathy and Haridas, Dhanya and Chugh, Seema and Batra, Surinder K
Advanced drug delivery reviews, ISSN 0169-409X, 01/2015, Volume 81, pp. 16 - 33
Therapy | miRNA | Diagnosis | Pathogenesis | Pancreatic cancer | MiRNA | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Animals | Prognosis | Pancreatic Neoplasms - diagnosis | Humans | Gene Expression Regulation, Neoplastic | Pancreatic Neoplasms - genetics | Survival Rate | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Molecular Targeted Therapy | Disease Progression | Pancreatic Neoplasms - therapy | Care and treatment | MicroRNA | Mortality | Tumor proteins | Health aspects | Cancer | Index Medicus
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