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Methods in Molecular Biology, ISSN 1064-3745, 2016, Volume 1431, pp. 109 - 126
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 02/2017, Volume 42, pp. 162 - 168
The linear molecules of DNA that constitute a eukaryotic genome have to be carefully organised within the nucleus to be able to correctly direct gene... 
NUCLEAR-ORGANIZATION | CHROMATIN | GENE | GENOME ARCHITECTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXITY | DYNAMICS | MODEL | CONFORMATION | DOMAINS | REVEALS | CELL BIOLOGY | Cell Nucleus - metabolism | Chromosomes - genetics | Humans | Molecular Conformation | Chromosomes - metabolism | Chromosomes - chemistry | Genome | Chromatin | Gene expression | Genes | Analysis | Genomics
Journal Article
Cell, ISSN 0092-8674, 11/2016, Volume 167, Issue 5, pp. 1369 - 1384.e19
Journal Article
Current Chemical Biology, ISSN 1872-3136, 12/2013, Volume 7, Issue 3, pp. 214 - 223
We have used the Smoldyn software to create spatially detailed models of the Escherichia coli chemotaxis pathway. With it we can follow signalling reactions at... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2007, Volume 129, Issue 43, pp. 12926 - 12927
Herein, we report the design, synthesis, biophysical evaluation with primary biological data of 3,8,10-trisubstituted isoalloxazines as a new class of... 
TELOMERIC DNA | RECOGNITION | MYC | TRANSCRIPTION | PROMOTER REGION | PROTOONCOGENE | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | Surface Plasmon Resonance | Flavins - chemistry | G-Quadruplexes | Ligands | Proto-Oncogene Proteins c-kit - genetics | Gene Expression | Vitamin B2 | Ligand binding (Biochemistry) | Research | Gene expression
Journal Article
Current Chemical Biology, ISSN 2212-7968, 2013, Volume 7, Issue 3, pp. 214 - 223
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2010, Volume 1, Issue 7, pp. 306 - 310
Herein, we demonstrate the design, synthesis, biophysical properties, and preliminary biological evaluation of 6-substituted indenoisoquinolines as a new class... 
c-kit regulation | inhibition | quadruplex | DNA | ligand | CHEMISTRY, MEDICINAL | SMALL-MOLECULE | TELOMERASE | TYROSINE KINASE | TRANSCRIPTION | ONCOGENE | HUMAN GENOME | MYC | TOPOISOMERASE-I INHIBITORS | BINDING
Journal Article
PLoS ONE, 10/2014, Volume 9, Issue 10
We present a computational model of transcription factor motion that explains both the observed rapid target finding of transcription factors, and how this... 
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 05/2000, Volume 182, Issue 10, pp. 2970 - 2972
Journal Article
Molecular Microbiology, ISSN 0950-382X, 12/2006, Volume 62, Issue 6, p. 1522
DNA processing reactions often involve multiple components acting in concert to achieve the desired outcome. However, it is usually difficult to know how the... 
Microbiology | Genetics | Mutation | Deoxyribonucleic acid--DNA
Journal Article
Molecular microbiology, ISSN 0950-382X, 12/2006, Volume 62, Issue 6, p. 1522
DNA processing reactions often involve multiple components acting in concert to achieve the desired outcome. However, it is usually difficult to know how the... 
DNA - genetics | DNA - chemistry | Transposases - metabolism | DNA Repair | DNA Transposable Elements - genetics | Electrophoretic Mobility Shift Assay | Mutagenesis, Insertional | DNA - metabolism | Mutation | Nucleic Acid Conformation | Binding Sites | DNA Cleavage
Journal Article
Molecular Cell, ISSN 1097-2765, 2004, Volume 13, Issue 4, pp. 537 - 547
DNA loops and bends are common features of DNA processing machines. The bacterial transposon Tn has recruited integration host factor (IHF), a site-specific... 
Journal Article
Molecular Microbiology, ISSN 0950-382X, 12/2006, Volume 62, Issue 6, pp. 1522 - 1533
DNA processing reactions often involve multiple components acting in concert to achieve the desired outcome. However, it is usually difficult to know how the... 
CATALYSIS | ACTIVATION | CONFORMATIONAL-CHANGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | IS903 TRANSPOSASE | INTERMEDIATE | MICROBIOLOGY | SYNAPTIC COMPLEX | SEPARATION | TN-10 TRANSPOSITION | IDENTIFICATION | CLEAVAGE | Gene mutations | DNA | Genetic aspects
Journal Article
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