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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2009, Volume 54, Issue 17, pp. 1609 - 1616
Objectives We sought to identify single nucleotide polymorphisms associated with mild statin-induced side effects. Background Statin-induced side effects can... 
Cardiovascular | Internal Medicine | clinical trial | hydroxymethylglutaryl-CoA reductase inhibitors | adverse events | single nucleotide polymorphisms | myopathy | pharmacogenetics | TRIALS | CARDIAC & CARDIOVASCULAR SYSTEMS | ACID | SAFETY | SLCO1B1 POLYMORPHISM | INDUCED MYOPATHY | ATORVASTATIN | PHARMACOKINETICS | DISEASE | PRAVASTATIN | LACTONE | Haplotypes | Pyrroles - pharmacokinetics | Simvastatin - adverse effects | Heptanoic Acids - pharmacokinetics | Humans | Middle Aged | Male | Heptanoic Acids - adverse effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Organic Anion Transporters - genetics | Pravastatin - adverse effects | Pyrroles - adverse effects | Female | Muscular Diseases - chemically induced | Hypolipidemic Agents - adverse effects | Creatine Kinase - blood | Simvastatin - pharmacokinetics | Muscular Diseases - blood | Atorvastatin Calcium | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Aged | Polymorphism, Single Nucleotide | Hypolipidemic Agents - pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Pravastatin - pharmacokinetics | Enzymes | Hypotheses | Acids | Mortality | Cardiovascular disease | Muscle pain | Drug therapy | Statins | Cholesterol | Index Medicus | Abridged Index Medicus | muscular diseases | hydroxymethylglutaryl-CoA Reductase Inhibitors
Journal Article
American Heart Journal, ISSN 0002-8703, 2012, Volume 163, Issue 5, pp. 844 - 850.e1
Background Cardiovascular risk models remain incomplete. Small-molecule metabolites may reflect underlying disease and, as such, serve as novel biomarkers of... 
Cardiovascular | NRI | Global Registry of Acute Coronary Events | myocardial infarction | net reclassification improvement | interquartile range | IQR | IDI | MURDOCK CV | PCA | Measurement to Understand the Reclassification of Disease of Cabarrus and Kannapolis Cardiovascular Study | GRACE | integrated discrimination index | hazard ratio | confidence interval | principal component analysis | IMPROVEMENTS | ASSOCIATION | CARDIAC & CARDIOVASCULAR SYSTEMS | Multivariate Analysis | Predictive Value of Tests | Confidence Intervals | Age Distribution | Prevalence | Prognosis | Blood Chemical Analysis | Humans | Middle Aged | Cardiac Catheterization - statistics & numerical data | Male | Lipids - blood | Cardiac Catheterization - methods | Cardiovascular Diseases - epidemiology | Adult | Female | Retrospective Studies | Cardiovascular Diseases - diagnosis | Severity of Illness Index | Cardiovascular Diseases - metabolism | Risk Assessment | Coronary Artery Disease - metabolism | Biomarkers - blood | Metabolomics - methods | Stroke Volume | Analysis of Variance | Coronary Artery Disease - diagnosis | Survival Analysis | Sex Distribution | Coronary Artery Disease - epidemiology | Cohort Studies | Medical research | Metabolites | Cardiac patients | Medicine, Experimental | Disease susceptibility | Coronary heart disease | Heart attack | Risk factors | Cardiovascular disease | Heart attacks | Cardiology | Mortality | Index Medicus | Abridged Index Medicus
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 10, pp. 1211 - 1213
Journal Article
by Assimes, Themistocles L., MD, PhD and Hólm, Hilma, MD and Kathiresan, Sekar, MD and Reilly, Muredach P., MB and Thorleifsson, Gudmar, PhD and Voight, Benjamin F., PhD and Erdmann, Jeanette, PhD and Willenborg, Christina, MSc and Vaidya, Dhananjay, MBBS, PhD, MPH and Xie, Changchun, PhD and Patterson, Chris C., PhD and Morgan, Thomas M., MD and Burnett, Mary Susan, PhD and Li, Mingyao, PhD and Hlatky, Mark A., MD and Knowles, Joshua W., MD, PhD and Thompson, John R., PhD and Absher, Devin, PhD and Iribarren, Carlos, MD, MPH, PhD and Go, Alan, MD and Fortmann, Stephen P., MD and Sidney, Stephen, MD, MPH and Risch, Neil, PhD and Tang, Hua, PhD and Myers, Richard M., PhD and Berger, Klaus, MD and Stoll, Monika, PhD and Shah, Svati H., MD, MHS and Thorgeirsson, Gudmundur, MD, PhD and Andersen, Karl, MD, PhD and Havulinna, Aki S., MSc and Herrera, J. Enrique, MS and Faraday, Nauder, MD and Kim, Yoonhee, PhD and Kral, Brian G., MD, MPH and Mathias, Rasika A., ScD and Ruczinski, Ingo, PhD and Suktitipat, Bhoom, MD and Wilson, Alexander F., PhD and Yanek, Lisa R., MPH and Becker, Lewis C., MD and Linsel-Nitschke, Patrick, MD and Lieb, Wolfgang, MD and König, Inke R., PhD and Hengstenberg, Christian, MD and Fischer, Marcus, MD and Stark, Klaus, PhD and Reinhard, Wibke, MD and Winogradow, Janina, MD and Grassl, Martina, MD and Grosshennig, Anika, MSc and Preuss, Michael, MSc and Schreiber, Stefan, MD and Wichmann, H.-Erich, MD and Meisinger, Christa, MD, MPH and Yee, Jean, BS and Friedlander, Yechiel, PhD and Do, Ron, MSc and Meigs, James B., MD, MPH and Williams, Gordon, MD and Nathan, David M., MD and MacRae, Calum A., MD, PhD and Qu, Liming, MS and Wilensky, Robert L., MD and Matthai, William H., MD and Qasim, Atif N., MD and Hakonarson, Hakon, MD, PhD and Pichard, Augusto D., MD and Kent, Kenneth M., MD, PhD and Satler, Lowell, MD and Lindsay, Joseph M., MD and Waksman, Ron, MD and Knouff, Christopher W., MD, PhD and Waterworth, Dawn M., PhD and Walker, Max C., BSc and Mooser, Vincent E., MD and Marrugat, Jaume, MD, PhD and Lucas, Gavin, PhD and Subirana, Isaac, MSc and Sala, Joan, MD and Ramos, Rafael, MD, PhD and Martinelli, Nicola, MD and Olivieri, Oliviero, MD and Trabetti, Elisabetta, PhD and Malerba, Giovanni, PhD and Pignatti, Pier Franco, MD and Guiducci, Candace, BS and Mirel, Daniel, PhD and Parkin, Melissa, BS and Hirschhorn, Joel N., MD, PhD and Asselta, Rosanna, PhD and Duga, Stefano, PhD and Musunuru, Kiran, MD, PhD, MPH and Daly, Mark J., PhD and Purcell, Shaun, PhD and Eifert, Sandra, MD and Braund, Peter S., MSc and Wright, Benjamin J., PhD and Balmforth, Anthony J., PhD and Ball, Stephen G., PhD and ... and Cardiogenics and Wellcome Trust Case Control and Myocardial Infarction Genet and Wellcome Trust Case Control Consortium and Myocardial Infarction Genetics Consortium and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and EpiHealth: Epidemiology for Health and Lund University and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 56, Issue 19, pp. 1552 - 1563
Objectives We sought to replicate the association between the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism (rs20455), and clinical coronary artery... 
Cardiovascular | Internal Medicine | coronary artery disease | polymorphism | KIF6 | kinesin-like protein 6 | myocardial infarction | OR | single nucleotide polymorphism | CI | CAD | Abbreviations and Acronyms | HR | odds ratio | SNP | hazard ratio | confidence interval | MI | POPULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | GENOMEWIDE ASSOCIATION | GENOTYPE DATA | HEART-DISEASE | GENE VARIANTS | CHROMOSOME 9P21.3 | CARDIOVASCULAR-DISEASE | NONFATAL MYOCARDIAL-INFARCTION | HEALTH | Humans | Middle Aged | Risk Factors | Tryptophan - genetics | Male | Coronary Artery Disease - enzymology | Case-Control Studies | Internationality | Arginine - genetics | Coronary Artery Disease - genetics | Kinesin - genetics | Polymorphism, Single Nucleotide - genetics | Female | Coronary Artery Disease - epidemiology | Genome-Wide Association Study - methods | Hypertension | Medical colleges | Medical research | Genetic disorders | Environmental health | Chronic diseases | Family medicine | Coronary heart disease | Population genetics | Biometry | Anopheles | Medicine, Experimental | Genetic aspects | Diabetes | Cardiology | Public health | Medical informatics | Kinesin | Heart | Heart attacks | African Americans | Cardiovascular disease | Genomes | Proteins | Studies | Confidence intervals | Consortia | International organizations | Ischemia | Womens health | Atherosclerosis | Age | Hispanics | Index Medicus | Abridged Index Medicus | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | myocardial | Medicin och hälsovetenskap | infarction | Klinisk medicin
Journal Article
American Heart Journal, ISSN 0002-8703, 2011, Volume 162, Issue 1, pp. 166 - 172.e1
Journal Article
American Heart Journal, ISSN 0002-8703, 2015, Volume 170, Issue 3, pp. 580 - 590.e28
Journal Article
American Heart Journal, ISSN 0002-8703, 2017
Abstract Background Variation of the rs6265 (Val66Met) single nucleotide polymorphism (SNP) on the BDNF gene has been related to a number of endophenotyes that... 
Cardiovascular
Journal Article
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2012, Volume 143, Issue 4, pp. 873 - 878
Journal Article
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2007, Volume 50, Issue 10, pp. 930 - 932
Journal Article
American Heart Journal, ISSN 0002-8703, 2010, Volume 160, Issue 3, pp. 371 - 379.e2
Journal Article