X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (7) 7
heterogeneity (3) 3
biopsy (2) 2
inhibition (2) 2
alterations (1) 1
anti-egfr therapy (1) 1
article (1) 1
autopsies (1) 1
autopsy (1) 1
biochemistry & molecular biology (1) 1
blockade (1) 1
braf (1) 1
case reports (1) 1
cell biology (1) 1
cell-free nucleic acids - blood (1) 1
cell-free nucleic acids - genetics (1) 1
cohort studies (1) 1
colorectal-cancer (1) 1
data acquisition (1) 1
deoxyribonucleic acid--dna (1) 1
dna (1) 1
dna, neoplasm - blood (1) 1
dna, neoplasm - genetics (1) 1
drug resistance, neoplasm - genetics (1) 1
ductal adenocarcinoma (1) 1
evolution (1) 1
female (1) 1
fibroblasts (1) 1
gastrointestinal neoplasms - blood (1) 1
gastrointestinal neoplasms - genetics (1) 1
gastrointestinal neoplasms - pathology (1) 1
genetic heterogeneity (1) 1
genomic landscape (1) 1
humans (1) 1
intratumor heterogeneity (1) 1
lesions (1) 1
liquid biopsy (1) 1
male (1) 1
medicine, research & experimental (1) 1
mek (1) 1
middle aged (1) 1
mutation (1) 1
mutations (1) 1
oncology (1) 1
proto-oncogene proteins b-raf - genetics (1) 1
resistance (1) 1
sequences (1) 1
signature (1) 1
somatic ercc2 mutations (1) 1
subtypes (1) 1
target acquisition (1) 1
targeted therapy (1) 1
therapy (1) 1
tumors (1) 1
whole exome sequencing (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 11/2019
Although represents the most commonly mutated oncogene, it has long been considered an "undruggable" target. Novel covalent inhibitors selective for the KRAS... 
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 09/2019, Volume 25, Issue 9, pp. 1415 - 1415
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1575 - 1575
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2019
Journal Article
Cancer Discovery, ISSN 2159-8274, 09/2018, Volume 8, Issue 9, pp. 1096 - 1111
Clinically relevant subtypes exist for pancreatic ductal adenocarcinoma (PDAC), but molecular characterization is not yet standard in clinical care. We... 
HETEROGENEITY | MEK | INHIBITION | ONCOLOGY | DUCTAL ADENOCARCINOMA | SUBTYPES | RESISTANCE | SOMATIC ERCC2 MUTATIONS | BRAF | SIGNATURE | FIBROBLASTS
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 01/2020, p. clincanres.3467.2019
ctDNA offers a promising, non-invasive approach to monitor therapeutic efficacy in real-time. We explored whether the quantitative percent change in ctDNA... 
Journal Article
Cancer Discovery, ISSN 2159-8274, 04/2018, Volume 8, Issue 4, pp. 417 - 427
Clonal heterogeneity associated with acquired resistance presents a critical therapeutic challenge. Whole-exome sequencing of paired tumor biopsies and... 
Journal Article
Cancer discovery, 04/2018, Volume 8, Issue 4, p. 417
Clonal heterogeneity associated with acquired resistance presents a critical therapeutic challenge. Whole-exome sequencing of paired tumor biopsies and... 
Journal Article
JCO Precision Oncology, ISSN 2473-4284, 11/2018, Issue 2, pp. 1 - 15
Purpose Third-generation epidermal growth factor receptor (EGFR) inhibitors like nazartinib are active against EGFR mutation–positive lung cancers with... 
Journal Article
JCO precision oncology, ISSN 2473-4284, 2018, Volume 2018
Third-generation epidermal growth factor receptor (EGFR) inhibitors like nazartinib are active against mutation-positive lung cancers with T790M-mediated... 
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.