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Nature Medicine, ISSN 1078-8956, 11/2010, Volume 16, Issue 11, pp. 1299 - 1304
Bitter taste receptors (TAS2Rs) on the tongue probably evolved to evoke signals for avoiding ingestion of plant toxins. We found expression of TAS2Rs on human... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | CONTRACTILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELAXATION | CELL BIOLOGY | HETEROGENEITY | LACTONES | ASTHMA | CHANNELS | MAMMALIAN TASTE | EXPRESSION | SPARKS | Asthma - metabolism | Large-Conductance Calcium-Activated Potassium Channels - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Bronchi - physiopathology | Myocytes, Smooth Muscle - pathology | RNA, Messenger - metabolism | Airway Obstruction - metabolism | Bronchi - drug effects | Dose-Response Relationship, Drug | Muscle, Smooth - drug effects | Muscle Relaxation - physiology | Bronchoconstriction - drug effects | Bronchi - metabolism | Bronchi - pathology | Myocytes, Smooth Muscle - metabolism | Membrane Potentials - drug effects | Bronchoconstriction - physiology | Asthma - physiopathology | Cell Separation | RNA, Messenger - genetics | Airway Obstruction - physiopathology | Muscle, Smooth - metabolism | Membrane Potentials - physiology | Taste - physiology | Gene Expression Regulation - drug effects | Animals | Taste - drug effects | Asthma - complications | Calcium Signaling - drug effects | Airway Obstruction - pathology | Muscle, Smooth - physiopathology | Mice | Receptors, G-Protein-Coupled - genetics | Muscle Relaxation - drug effects | Muscle, Smooth - pathology | Saccharin - pharmacology | Taste buds | Care and treatment | Usage | Animal models in research | Physiological aspects | Smooth muscle | Genetic aspects | Airway obstruction (Medicine) | Research | Risk factors | Signal transduction | Taste | Calcium | Cellular biology | Respiratory diseases
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 12/2018, Volume 315, Issue 6, pp. F1592 - F1600
Myogenic contraction of renal arterioles is an important regulatory mechanism for renal blood flow autoregulation. We have previously demonstrated that... 
Confocal fluorescence microscopy | Myogenic response | Integrin | TMEM16A | Afferent arteriole
Journal Article
American Journal of Physiology-Cell Physiology, ISSN 0363-6143, 08/2012, Volume 303, Issue 3, pp. C233 - C235
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 10/2013, Volume 305, Issue 7, pp. C704 - C715
Transient receptor potential vanilloid 4 (TRPV4) is a mechanosensitive channel in pulmonary arterial smooth muscle cells (PASMCs). Its upregulation by chronic... 
Serotonin | Pulmonary arteries | TRPV4 | Chronic hypoxia | Pulmonary hypertension | ARACHIDONIC-ACID RELEASE | PHYSIOLOGY | MICE LACKING TRPV4 | pulmonary hypertension | PROTEIN-KINASE | INDUCED LUNG INJURY | FUNCTIONAL-ROLE | INDUCED UP-REGULATION | CELL BIOLOGY | serotonin | chronic hypoxia | PHOSPHOLIPASE A ACTIVATION | ENDOTHELIAL-CELLS | pulmonary arteries | SMOOTH-MUSCLE-CELLS | RECEPTOR POTENTIAL VANILLOID-4 | Hypertension, Pulmonary - physiopathology | Male | Serotonin - pharmacology | Hypoxia - metabolism | Dose-Response Relationship, Drug | TRPV Cation Channels - metabolism | Pulmonary Artery - metabolism | Time Factors | TRPV Cation Channels - antagonists & inhibitors | Disease Models, Animal | Vasoconstrictor Agents - pharmacology | Mice, Inbred C57BL | Morpholines - pharmacology | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary - genetics | Hypertension, Pulmonary - metabolism | Hypoxia - complications | Pulmonary Artery - physiopathology | Pulmonary Artery - drug effects | Sulfonamides - pharmacology | Vasoconstriction - drug effects | TRPV Cation Channels - genetics | Mice, Knockout | Pyrroles - pharmacology | Animals | Calcium Signaling - drug effects | Mice | Chronic Disease | Hypertension, Pulmonary - etiology | Physiological aspects | Smooth muscle | Hypoxia | Ion channels | Health aspects | Pulmonary artery
Journal Article
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 04/2014, Volume 306, Issue 7, pp. C659 - C659
Intracellular calcium (...) plays pivotal roles in distinct cellular functions through global and local signaling in various subcellular compartments, and... 
Journal Article
American Journal of Physiology, ISSN 0363-6143, 04/2014, Volume 306, Issue 7, p. C659
  Intracellular calcium (...) plays pivotal roles in distinct cellular functions through global and local signaling in various subcellular compartments, and... 
Signal transduction | Calcium | Rodents | Glycoproteins | T cell receptors | Cells | Cytoplasm
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 03/2012, Volume 302, Issue 6, pp. L555 - L568
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 06/2018, Volume 365, Issue 3, pp. 544 - 555
Pulmonary hypertension (PH) is characterized by enhanced vasoconstriction and vascular remodeling, which are attributable to the alteration of Ca2+ homeostasis... 
CHANNEL FUNCTION | STIM1 | PROSTATE-CANCER | TRP CHANNELS | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | CAPACITATIVE CA2+ ENTRY | UP-REGULATION | EXPRESSION | VASOCONSTRICTION | VASCULAR-TONE
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2003, Volume 285, Issue 6, pp. H2552 - H2562
Journal Article
Cardiovascular Research, ISSN 0008-6363, 2016, Volume 111, Issue 1, pp. 94 - 104
Store-operated Ca2+ entry (SOCE) contributes to a multitude of physiological and pathophysiological functions in pulmonary vasculatures. SOCE attributable to... 
Canonical transient receptor potential 1 (TRPC1) | Stromal interaction molecule 1 (STIM1) | Store-operated Ca | entry (SOCE) | Ryanodine receptor (RyR) | Pulmonary arterial smooth muscle cells | RELEASE CHANNELS | 4-CHLORO-M-CRESOL | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | SARCOPLASMIC-RETICULUM | CAPACITATIVE CA2+ ENTRY | INDUCED UP-REGULATION | SKELETAL-MUSCLE | SMOOTH-MUSCLE-CELLS | INOSITOL TRISPHOSPHATE | CANINE PULMONARY | Store-operated Ca2+ entry (SOCE) | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Humans | Male | Ryanodine Receptor Calcium Release Channel - metabolism | Stromal Interaction Molecule 1 - genetics | Pulmonary Artery - metabolism | Transfection | RNA Interference | Time Factors | HEK293 Cells | Myocytes, Smooth Muscle - drug effects | TRPC Cation Channels - genetics | Myocytes, Smooth Muscle - metabolism | Muscle, Smooth, Vascular - drug effects | ORAI1 Protein - metabolism | ORAI1 Protein - genetics | Ryanodine Receptor Calcium Release Channel - drug effects | Pulmonary Artery - drug effects | Calcium Channel Blockers - pharmacology | Stromal Interaction Molecule 1 - metabolism | Animals | Membrane Potentials | Ryanodine Receptor Calcium Release Channel - genetics | Calcium Signaling - drug effects | Ryanodine Receptor Calcium Release Channel - chemistry | TRPC Cation Channels - metabolism | Protein Binding | Calcium Channel Agonists - pharmacology | Protein Conformation | Mutation | Ion Channel Gating - drug effects | ORIGINAL ARTICLES
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 04/2014, Volume 306, Issue 7, pp. C659 - C669
Subedi KP, Paudel O, Sham JS. Detection of differentially regulated subsarcolemmal calcium signals activated by vasoactive agonists in rat pulmonary artery... 
FRET | Cameleon | Endothelin | Angiotensin | PROTEIN-KINASE-C | PHYSIOLOGY | Ca2+ signaling | CARDIAC MYOCYTES | NUCLEAR CALCIUM | CELL BIOLOGY | SARCOPLASMIC-RETICULUM CALCIUM | endothelin | RYANODINE RECEPTORS | IN-VIVO | FLUORESCENT INDICATORS | angiotensin | GATED CA2+ STORES | GROWTH-FACTOR | NUCLEOPLASMIC RETICULUM | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Endothelin-1 - pharmacology | Cytoplasm - metabolism | Inositol 1,4,5-Trisphosphate - pharmacology | Male | Recombinant Fusion Proteins - metabolism | Pulmonary Artery - metabolism | Cell Nucleus - metabolism | Transfection | Fluorescence Resonance Energy Transfer | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Sarcolemma - metabolism | Muscle, Smooth, Vascular - drug effects | Calcium-Binding Proteins - metabolism | Excitation Contraction Coupling - drug effects | Vasoconstrictor Agents - pharmacology | Angiotensin II - pharmacology | Cells, Cultured | Rats | Platelet-Derived Growth Factor - pharmacology | Pulmonary Artery - drug effects | Vasoconstriction - drug effects | Microscopy, Confocal | Animals | Calcium Signaling - drug effects | Sarcolemma - drug effects | Biosensing Techniques | Recombinant Fusion Proteins - genetics | Kinetics | Nucleoplasmins - metabolism | Cell Nucleus - drug effects | Cytoplasm - drug effects | Nucleoplasmins - genetics | Calcium-Binding Proteins - genetics | Calcium, Dietary | Physiological aspects | Smooth muscle | Muscle cells | Physiological research | Cellular signal transduction | Research | Pulmonary artery | cameleon
Journal Article
Circulation Research, ISSN 0009-7330, 09/2004, Volume 95, Issue 5, pp. 496 - 505
Journal Article