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Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. SY19-02 - SY19-02
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 2347 - 2347
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2017, Volume 32, Issue 6, pp. 721 - 723
In this issue of , Gong et al. have analyzed the sensitivity of 560 cell lines to the selective CDK4/6 inhibitor abemaciclib and have defined cancers with... 
BREAST-CANCER | CDK6 | SOLID TUMORS | ONCOLOGY | KINASE | CELL BIOLOGY | Aminopyridines | Benzimidazoles | Protein Kinase Inhibitors | Genomics | Humans | Biomarkers | Cyclin-Dependent Kinase 4 | Cyclin-Dependent Kinase 6 | Cyclins | Index Medicus
Journal Article
Expert Opinion on Therapeutic Targets, ISSN 1472-8222, 11/2010, Volume 14, Issue 11, pp. 1199 - 1212
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2014, Volume 371, Issue 21, pp. 1963 - 1971
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 10, pp. 1011 - 1019
Journal Article
CANCER DISCOVERY, ISSN 2159-8274, 10/2013, Volume 3, Issue 10, pp. 1089 - 1089
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e90353 - e90353
Background: In advanced cancers, transforming growth factor-beta (TGFb) promotes tumor growth and metastases and suppresses host antitumor immunity. GC1008 is... 
SURVIVAL | EPITHELIAL-MESENCHYMAL TRANSDIFFERENTIATION | INHIBITION | SOLID TUMORS | EFFICACY | VIVO | MULTIDISCIPLINARY SCIENCES | METASTATIC BREAST-CANCER | KERATOACANTHOMAS | T-CELLS | PROGRESSION | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Male | Tomography, X-Ray Computed | Antineoplastic Agents - therapeutic use | Positron-Emission Tomography | Kidney Neoplasms - diagnosis | Aged, 80 and over | Transforming Growth Factor beta - antagonists & inhibitors | Adult | Female | Antineoplastic Agents - pharmacology | Carcinoma, Renal Cell - drug therapy | Carcinoma, Renal Cell - pathology | Antibodies, Monoclonal - pharmacology | Treatment Outcome | Melanoma - pathology | Transforming Growth Factor beta - blood | Carcinoma, Renal Cell - diagnosis | Melanoma - drug therapy | Kidney Neoplasms - pathology | Aged | Kidney Neoplasms - drug therapy | Neoplasm Staging | Oncology, Experimental | Melanoma | Clinical trials | Monoclonal antibodies | Bone morphogenetic proteins | Research | Carcinoma, Renal cell | Metastasis | Transforming growth factors | Cancer | Intravenous administration | Toxicity | Transforming growth factor-b | Medical treatment | Transforming growth factor-a | Pharmacology | Patients | Immunity | Constraining | Metastases | Anticancer properties | Isoforms | Biomarkers | Antitumor activity | Bioindicators | Safety | Clear cell-type renal cell carcinoma | Index Medicus
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2011, Volume 12, Issue 11, pp. 1004 - 1012
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2010, Volume 363, Issue 18, pp. 1693 - 1703
A small group of patients with non–small-cell lung cancer have genetic lesions that activate anaplastic lymphoma kinase (ALK). Crizotinib, an orally... 
ALK | MEDICINE, GENERAL & INTERNAL | GEFITINIB | EML4-ALK FUSION GENE | 2ND-LINE TREATMENT | PHASE-II | EGFR MUTATIONS | IDENTIFICATION | TUMORS | ACTIVATING MUTATIONS | IMMUNOHISTOCHEMISTRY | Lung Neoplasms - drug therapy | Pyrazoles - therapeutic use | Microtubule-Associated Proteins - genetics | Humans | Middle Aged | Receptors, Growth Factor - antagonists & inhibitors | Lung Neoplasms - pathology | Male | Protein Kinase Inhibitors - adverse effects | Protein-Tyrosine Kinases - genetics | Pyridines - adverse effects | Serine Endopeptidases - genetics | Cell Cycle Proteins - genetics | Adult | Female | Pyrazoles - adverse effects | Pyridines - therapeutic use | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Pyridines - administration & dosage | Administration, Oral | Carcinoma, Non-Small-Cell Lung - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Kaplan-Meier Estimate | In Situ Hybridization, Fluorescence | Receptor Protein-Tyrosine Kinases | Disease Progression | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Oncogene Proteins, Fusion - genetics | Protein Kinase Inhibitors - therapeutic use | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Care and treatment | Lung cancer, Small cell | Genetic aspects | Diagnosis | Health aspects | Phosphotransferases | Lymphomas | Pharmaceutical industry | Lung cancer | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 575 - 575
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1620 - 1620
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 2729 - 2729
Checkpoint kinase 1 (CHK1) inhibitors are currently under investigation as chemopotentiating agents due to the role of CHK1 in establishing DNA damage... 
Journal Article