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Journal Article
Oncology Times, ISSN 0276-2234, 04/2018, Volume 40, Issue 7, pp. 14 - 15
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2015, Volume 21, Issue 6, pp. 1240 - 1242
Tumor mechanisms of abiraterone resistance in clinical prostate cancer are not well defined. Chen and colleagues report that a T878A androgen receptor mutation... 
INHIBITION | ONCOLOGY | MUTATION | CONSEQUENCES | CYP17 | RESISTANT PROSTATE-CANCER | ACETATE | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Receptors, Androgen - genetics | Humans | Progesterone - metabolism | Androstenes - therapeutic use | Male | Prostatic Neoplasms, Castration-Resistant - drug therapy | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 3452 - 3452
Journal Article
Journal of Clinical Immunology, ISSN 0271-9142, 5/2014, Volume 34, Issue 4, pp. 478 - 490
Journal Article
Physics of Fluids, ISSN 1070-6631, 05/2016, Volume 28, Issue 5, p. 53107
Journal Article
European Urology, ISSN 0302-2838, 07/2019
Journal Article
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7560, pp. 347 - 351
Prostate cancer resistance to castration occurs because tumours acquire the metabolic capability of converting precursor steroids to 5... 
ANDROGEN RECEPTOR | 3-BETA-HYDROXYSTEROID DEHYDROGENASE | CYP17A1 INHIBITION | MECHANISM | TESTOSTERONE | RATIONALE | MULTIDISCIPLINARY SCIENCES | INCREASED SURVIVAL | CHEMOTHERAPY | EXPOSURE | ENZALUTAMIDE | Chromatin - metabolism | Prostatic Neoplasms - metabolism | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Androgen Receptor Antagonists - therapeutic use | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Androgens - biosynthesis | Male | Androstenes - pharmacology | Androgen Receptor Antagonists - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Biotransformation | Cell Division | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Prostatic Neoplasms - drug therapy | Dihydrotestosterone - metabolism | Phenylthiohydantoin - pharmacology | Prostatic Neoplasms - pathology | Androstenes - therapeutic use | 5-alpha Reductase Inhibitors - therapeutic use | Prostatic Neoplasms, Castration-Resistant - drug therapy | Phenylthiohydantoin - analogs & derivatives | Androgen Receptor Antagonists - metabolism | Xenograft Model Antitumor Assays | Androstenes - chemistry | Animals | Biosynthetic Pathways - drug effects | Survival Analysis | 5-alpha Reductase Inhibitors - pharmacology | Androstenes - metabolism | Prostatic Neoplasms - enzymology | Mice | Steroid 17-alpha-Hydroxylase - metabolism | 5-alpha Reductase Inhibitors - metabolism | Androgens - metabolism | Enzymes | Testosterone | Androgens | Metabolites | Ligands | Gene expression | Prostate cancer | Tumors | Index Medicus
Journal Article
NATURE REVIEWS UROLOGY, ISSN 1759-4812, 05/2015, Volume 12, Issue 5, pp. 245 - U28
The ELM-PC 5 phase III randomized, double blind, multicentre trial comparing treatment with orteronel plus prednisone with placebo plus prednisone failed to... 
TRIAL | ANDROGEN RECEPTOR | RATIONALE | UROLOGY & NEPHROLOGY | RESISTANT PROSTATE-CANCER | ORTERONEL TAK-700 | EXPOSURE | ABIRATERONE | Corticosteroids | Cytochrome P-450 | Physiological aspects | Development and progression | Prednisone | Dosage and administration | Drug therapy | Health aspects | Prostate cancer
Journal Article
Journal Article