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Molecular Cancer Therapeutics, ISSN 1535-7163, 07/2007, Volume 6, Issue 7, pp. 2012 - 2021
With the development of targeted therapeutics, especially for small-molecule inhibitors, it is important to understand whether the observed in vivo efficacy... 
kinase inhibitor | Pharmacodynamics | pazopanib | angiogenesis | VEGF | TARGET | ONCOLOGY | FACTOR RECEPTORS | EXPRESSION | CANCER | TUMORS | RENAL-CELL CARCINOMA | ENDOTHELIAL GROWTH-FACTOR | Pyrimidines - blood | Humans | Fibroblast Growth Factor 2 - pharmacology | Antineoplastic Agents - administration & dosage | Indazoles - administration & dosage | Sulfones - pharmacology | Neovascularization, Pathologic - pathology | Phosphotyrosine - metabolism | Dose-Response Relationship, Drug | Sulfonamides - blood | Inhibitory Concentration 50 | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Cornea - pathology | Phosphorylation - drug effects | Sulfones - blood | Vascular Endothelial Growth Factor A - pharmacology | Protein Kinase Inhibitors - pharmacokinetics | Pyrimidines - administration & dosage | Pyrimidines - pharmacology | Sulfones - pharmacokinetics | Sulfonamides - pharmacology | Protein Kinase Inhibitors - blood | Sulfonamides - pharmacokinetics | Indazoles - pharmacology | Protein Kinase Inhibitors - administration & dosage | Indazoles - blood | Animals | Indazoles - pharmacokinetics | Cell-Free System | Mice, Nude | Antineoplastic Agents - blood | Cell Line, Tumor | Pyrimidines - pharmacokinetics | Mice | Protein Kinase Inhibitors - pharmacology | Sulfonamides - administration & dosage | Sulfones - administration & dosage
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 4726 - 4726
Abstract Abstract 4726 The thrombopoietin receptor agonists (TPO-RA), romiplostim and eltrombopag, are presently indicated for the treatment of certain patient... 
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2010, Volume 6, Issue 1, pp. 347 - n/a
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2008, Volume 51, Issue 15, pp. 4632 - 4640
Journal Article
Psychological Assessment, ISSN 1040-3590, 9/1999, Volume 11, Issue 3, pp. 326 - 338
A child version of the Positive and Negative Affect Schedule (PANAS; D. Watson, L. A. Clark, & A. Tellegen, 1988 ), the PANAS-C, was developed using students... 
PSYCHOMETRIC PROPERTIES | EMOTIONAL STATES | SELF-REPORTS | ADOLESCENTS | TRIPARTITE MODEL | DEPRESSIVE SYMPTOMS | ANXIETY DISORDERS | CLINICAL-ASSESSMENT | MANIFEST ANXIETY | COGNITIVE CONTENT-SPECIFICITY | PSYCHOLOGY, CLINICAL | Psychometrics | Child psychology | Research
Journal Article
Future Oncology, ISSN 1479-6694, 01/2015, Volume 11, Issue 2, pp. 193 - 203
Background: N-acetyl-glucosaminidase (NAG) is a potential marker of genotoxicity. We retrospectively analyzed plasma NAG and clinico-pathologic features in... 
senescence | NAG | biomarkers | fluoropyrimidines | cancer | aging | gastrointestinal adenocarcinoma | BIOMARKER | DNA-DAMAGE | ONCOLOGY | N-acetyl-glucosaminidase | DYSFUNCTION | EXPRESSION | TELOMERE LENGTH
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 01/1997, Volume 34, Issue 1, pp. 145 - 151
A series of novel 1,3‐diamino‐7,8,9,10‐tetrahydropyrido[3,2‐f]quinazolines were synthesized starting from 6‐amino‐5‐cyanoquinoline (4). These compounds... 
RESISTANCE | CHEMISTRY, ORGANIC | RECENT PROGRESS | PNEUMOCYSTIS-CARINII PNEUMONIA | RESOLUTION | TRIMETREXATE
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/1996, Volume 39, Issue 4, pp. 892 - 903
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 09/1995, Volume 32, Issue 5, pp. 1461 - 1465
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 01/1999, Volume 36, Issue 1, pp. 145 - 148
Novel 2,4‐diamino‐6‐methyl‐5‐ethynylpyrimidines were prepared via palladium catalyzed coupling of 2,4‐diamino‐5‐iodo‐6‐methyl‐pyrimidine with terminal... 
CHEMISTRY, ORGANIC | PNEUMONIA
Journal Article