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1. Full Text The final steps of integrin activation: the end game
by Shattil, Sanford J and Ginsberg, Mark H and Kim, Chungho
Nature reviews. Molecular cell biology, ISSN 1471-0072, 04/2010, Volume 11, Issue 4, pp. 288 - 300
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cytoplasm - metabolism | Animals | Signal Transduction | Talin - metabolism | Integrins - metabolism | Humans | Physiological aspects | Embryonic development | Research | Integrins | Index Medicus
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2. Full Text Integrin-based therapeutics: Biological basis, clinical use and new drugs
by Ley, Klaus and Rivera-Nieves, Jesus and Sandborn, William J and Shattil, Sanford
Nature reviews. Drug discovery, ISSN 1474-1776, 03/2016, Volume 15, Issue 3, pp. 173 - 183
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Cardiovascular Diseases - drug therapy | Humans | Integrins - immunology | Drug Discovery - trends | Drug Discovery - methods | Cardiovascular Diseases - immunology | Animals | Antibodies, Monoclonal - administration & dosage | Binding Sites - immunology | Multiple Sclerosis - immunology | Clinical Trials as Topic - methods | Antibodies, Monoclonal - immunology | Binding Sites - drug effects | Integrins - antagonists & inhibitors | Multiple Sclerosis - drug therapy | Pharmaceutical research | Molecular targeted therapy | Health aspects | Innovations | Integrins | Index Medicus
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3. Full Text The GPIIb/IIIa (integrin {alpha}IIb{beta}3) odyssey: A technology-driven saga of a receptor with twists, turns, and even a bend
by Coller, Barry S and Shattil, Sanford J
Blood, ISSN 0006-4971, 10/2008, Volume 112, Issue 8, pp. 3011 - 3025
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Biological and medical sciences | Medical sciences | Hematology - history | History, 21st Century | History, 20th Century | Humans | Platelet Aggregation | Thrombasthenia - diagnosis | Animals | Medical Laboratory Science | Hematology - methods | Thrombasthenia - genetics | Fibrinogen - metabolism | Platelet Aggregation Inhibitors - pharmacology | Platelet Glycoprotein GPIIb-IIIa Complex - genetics | Platelet Glycoprotein GPIIb-IIIa Complex - chemistry | Index Medicus | Abridged Index Medicus | ASH 50th Anniversary Review
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4. Full Text Talin Binding to Integrin β Tails: A Final Common Step in Integrin Activation
by Seiji Tadokoro and Sanford J. Shattil and Koji Eto and Vera Tai and Robert C. Liddington and José M. de Pereda and Mark H. Ginsberg and David A. Calderwood
Science (American Association for the Advancement of Science), ISSN 0036-8075, 10/2003, Volume 302, Issue 5642, pp. 103 - 106
Cytometry | NIH 3T3 cells | Plasmids | Stem cells | Cell adhesion | Ligands | Agonists | Reports | Physiological regulation | CHO cells | Integrins | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Signal transduction | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Humans | Integrin beta3 - chemistry | Molecular Sequence Data | Integrin beta1 - chemistry | Transfection | Platelet Glycoprotein GPIIb-IIIa Complex - metabolism | Platelet Glycoprotein GPIIb-IIIa Complex - chemistry | Antibodies, Monoclonal - immunology | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Integrin beta Chains - chemistry | Platelet Glycoprotein GPIIb-IIIa Complex - immunology | Signal Transduction | Talin - metabolism | Fibronectins - metabolism | Integrin beta1 - metabolism | Integrin beta3 - metabolism | Animals | Protein Binding | Integrin beta Chains - metabolism | Protein Conformation | RNA, Small Interfering | Mutation | Amino Acid Substitution | Index Medicus
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5. Full Text Optogenetic interrogation of integrin αVβ3 function in endothelial cells
by Liao, Zhongji and Kasirer-Friede, Ana and Shattil, Sanford J
Journal of cell science, ISSN 0021-9533, 2017, Volume 130, Issue 20, pp. 3532 - 3541
Optogenetics | Integrin function | Vascular biology | Kindlin-2 | Gene Expression | Mice, Inbred C57BL | Cells, Cultured | Talin - metabolism | Cell Adhesion | Integrin alphaVbeta3 - metabolism | Animals | Integrin alphaVbeta3 - genetics | Fibrinogen - metabolism | Muscle Proteins - metabolism | Protein Binding | Cytoskeletal Proteins - metabolism | Endothelial Cells - physiology | Neovascularization, Physiologic | Cell Movement | Binding | Phosphoinositides | Adapters | Fluorescence | Optics | Src protein | Endothelial cells | Mutants | Cell adhesion & migration | Angiogenesis | Microscopy | Actin | Interrogation | Information processing | Genetics | Microvasculature | Immunofluorescence | Cell migration | Index Medicus | 129 | 127
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6. Full Text The Mechanism of Kindlin-Mediated Activation of Integrin αIIbβ3
by Ye, Feng and Petrich, Brian G and Anekal, Praju and Lefort, Craig T and Kasirer-Friede, Ana and Shattil, Sanford J and Ruppert, Raphael and Moser, Markus and Fässler, Reinhard and Ginsberg, Mark H
Current biology, ISSN 0960-9822, 11/2013, Volume 23, Issue 22, pp. 2288 - 2295
Protein Structure, Tertiary | Recombinant Proteins - metabolism | Cytoskeletal Proteins - genetics | Membrane Proteins - genetics | Humans | Recombinant Proteins - genetics | Neoplasm Proteins - metabolism | Animals | Blood Platelets - metabolism | Platelet Glycoprotein GPIIb-IIIa Complex - metabolism | HEK293 Cells | Cytoskeletal Proteins - metabolism | Ligands | Membrane Proteins - metabolism | Mice | Neoplasm Proteins - genetics | Platelet Glycoprotein GPIIb-IIIa Complex - genetics | Index Medicus | kindlin | integrin | talin signal transduction | cell adhesion
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