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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2016, Volume 113, Issue 34, pp. E4966 - E4975
Journal Article
The FEBS journal, ISSN 1742-464X, 12/2017, Volume 284, Issue 23, pp. 4083 - 4095
Oxidative damage resulting from increased lipid peroxidation (LPO) is considered an important factor in the development of late onset/age-related Alzheimer’s... 
deuterium-based therapeutics | cognition | Alzheimer’s disease | lipid peroxidation | polyunsaturated fatty acid
Journal Article
BioEssays, ISSN 0265-9247, 12/2007, Volume 29, Issue 12, pp. 1247 - 1256
Journal Article
Movement Disorders, ISSN 0885-3185, 06/2018, Volume 33, Issue 6, pp. 1000 - 1005
Background: RT001 is a deuterated ethyl linoleate that inhibits lipid peroxidation and is hypothesized to reduce cellular damage and recover mitochondrial... 
FRDA | treatment | POLYUNSATURATED FATTY-ACIDS | AUTOXIDATION | CLINICAL NEUROLOGY | Clinical trials | Unsaturated fatty acids | Ataxia | Arachidonic acid | Lubrication and lubricants
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 08/2016, Volume 113, Issue 34, pp. E4966 - E4966
Ferroptosis is form of regulated nonapoptotic cell death that is involved in diverse disease contexts. Small molecules that inhibit glutathione peroxidase 4... 
Journal Article
The FEBS Journal, ISSN 1742-464X, 12/2017, Volume 284, Issue 23, pp. 4083 - 4095
Oxidative damage resulting from increased lipid peroxidation ( LPO ) is considered an important factor in the development of late onset/age‐related Alzheimer's... 
deuterium‐based therapeutics | cognition | Alzheimer's disease | lipid peroxidation | polyunsaturated fatty acid | deuterium-based therapeutics | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUSCEPTIBILITY | BRAIN PROTEINS | ALDEHYDE DEHYDROGENASE INCREASES | PROTEOMIC IDENTIFICATION | DEFICIENCY | DAMAGE | OXIDATIVE STRESS HYPOTHESIS | FLUID | PRODUCT | Memory - drug effects | Alzheimer Disease - physiopathology | Humans | Deuterium - chemistry | Aldehyde Dehydrogenase, Mitochondrial - metabolism | Fatty Acids, Unsaturated - pharmacology | F2-Isoprostanes - metabolism | Hippocampus - drug effects | Cognition - drug effects | Hydrogenation | Aldehyde Dehydrogenase, Mitochondrial - genetics | Mice, Knockout | Hippocampus - metabolism | Animals | Fatty Acids, Unsaturated - chemistry | Alzheimer Disease - prevention & control | Lipid Peroxidation - drug effects | Cognition - physiology | Alzheimer Disease - genetics | Hippocampus - physiopathology | Disease Models, Animal | Fatty Acids, Unsaturated - administration & dosage | Memory - physiology | Unsaturated fatty acids | Analysis | Deuterium | Oxidative stress | Reactive oxygen species | Fish oils | Neurodegenerative diseases | Polyunsaturated fatty acids | Memory | Cognitive ability | Lipid peroxidation | Cognition | Chemical compounds | Fatty acids | Aldehyde dehydrogenase | Isoprostanes | Rodents | Acid resistance | Mice | Alzheimers disease | Age | Peroxidation
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2016, Volume 113, Issue 34, p. E4966
  Ferroptosis is form of regulated nonapoptotic cell death that is involved in diverse disease contexts. Small molecules that inhibit glutathione peroxidase 4... 
Molecules | Hydrogen | Lipid peroxidation | Fatty acids | Substrates | Apoptosis
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2014, Volume 76, p. S4
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2014, Volume 76, p. S4
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2014, Volume 76, pp. S4 - S4
Journal Article
BioEssays, ISSN 0265-9247, 12/2007, Volume 29, Issue 12, pp. 1247 - 1256
Journal Article
Journal Article
Frontiers in physiology, ISSN 1664-042X, 2019, Volume 10, p. 641
Chemically reinforced essential fatty acids (FAs) promise to fight numerous age-related diseases including Alzheimer's, Friedreich's ataxia and other... 
Lipid peroxidation | Unsaturated fatty acids | Nutrition | Hydrogen | Requirements | deuterated fatty acid | C. elegans | lipid peroxidation | lifespan | oxidative stress | polyunsaturated fatty acid (PUFA)
Journal Article
REJUVENATION RESEARCH, ISSN 1549-1684, 03/2007, Volume 10, Issue 1, pp. 47 - 59
A method is proposed that has the potential to lessen detrimental damages caused by reactive oxygen species (ROS) to proteins, nucleic acids, lipids, and other... 
METHYLATION | ENDOGENOUS OXIDATIVE DAMAGE | HUMAN-DISEASE | PEROXYNITRITE | ALCOHOL-DEHYDROGENASE | DNA-DAMAGE | FATTY-ACIDS | PROTEINS | MASS-SPECTROMETRY | DEUTERIUM | GERIATRICS & GERONTOLOGY | Reactive Nitrogen Species | Reactive Oxygen Species | Oxidation-Reduction | Isotopes | Longevity - physiology | Nucleic Acids
Journal Article
The FEBS Journal, ISSN 1742-464X, 08/2018, Volume 285, Issue 16, pp. 3002 - 3012
Huntington's disease ( HD ) is an autosomal dominant neurodegenerative disease which has no effective treatment and is characterized by psychiatric disorders,... 
D‐PUFA | Huntington's disease | Q140 mouse | lipid peroxidation | polyunsaturated fatty acid | D-PUFA | CONTROLLED-TRIAL | PROOXIDANT | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | ALPHA-TOCOPHEROL | PATHOLOGY | EARLY MOTOR | ANTIOXIDANT | POLYUNSATURATED FATTY-ACIDS | DYSFUNCTION | Cognitive Dysfunction - diet therapy | Cognitive Dysfunction - metabolism | Body Weight - drug effects | Deuterium - chemistry | Motor Activity - drug effects | Fatty Acids, Unsaturated - pharmacology | Linoleic Acid - chemistry | Male | Mice, Transgenic | Huntington Disease - etiology | Animals | Deuterium - pharmacology | Fatty Acids, Unsaturated - chemistry | Lipid Peroxidation - drug effects | Female | Huntingtin Protein - genetics | Linoleic Acid - pharmacology | Dietary Supplements | Disease Models, Animal | Lipid peroxidation | Unsaturated fatty acids | Nervous system diseases | Mental illness | Analysis | Deuterium | Huntingtons disease | Oxidative stress | Animal models | Mental disorders | Huntingtin | Polyunsaturated fatty acids | Cognitive ability | Medical services | Motors | Antioxidants | Autoxidation | Rodents | Neostriatum | Dementia disorders | Peroxidation | Fish oils | Neurodegenerative diseases | Medical treatment | Pattern recognition | Object recognition | Fatty acids | Chemical compounds | Linoleic acid | Neurological diseases | Isoprostanes
Journal Article