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European Journal of Neuroscience, ISSN 0953-816X, 04/2009, Volume 29, Issue 7, pp. 1335 - 1347
The mechanism by which aggregates of the [beta]-amyloid peptide (A[beta]) mediate their toxicity is uncertain. We show here that the expression of the... 
Aggregation | Iron | Hydroxy radical | Chelation therapy | Oxidative stress | Neurosciences | Hydroxides | Peptides | Radicals (Chemistry) | Analysis | Drosophila | Ferritin | Binding proteins | Medical screening | Drug therapy | Alzheimer's disease
Journal Article
Neuropharmacology, ISSN 0028-3908, 04/2014, Volume 79, pp. 307 - 313
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 08/2017, Volume 25, Issue 8, pp. 1866 - 1880
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2, p. e0115369
Journal Article
Journal Article
Journal Article
Cell, ISSN 0092-8674, 04/1999, Volume 97, Issue 3, pp. 395 - 406
The amyloid-̄ precursor protein (APP) is directly and efficiently cleaved by caspases during apoptosis, resulting in elevated amyloid-̄ (Ā) peptide formation.... 
ICE/CED-3 PROTEASE | SPECIFICITIES | RAT | APOPTOTIC CELL-DEATH | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | COMBINATORIAL APPROACH | MODEL | DAMAGE | BRAIN | TRANSGENIC MICE | CELL BIOLOGY | Excitatory Amino Acid Agonists | Rats, Wistar | Apoptosis - drug effects | Humans | Apoptosis - genetics | Male | Neurons - cytology | Aspartic Acid | Caspases - analysis | Alzheimer Disease - pathology | Brain Diseases - chemically induced | Kainic Acid | Mutation - physiology | Sweden | Caspases - metabolism | Amyloid beta-Peptides - genetics | Amyloidosis - genetics | Aspartic Acid Endopeptidases | Amyloid Precursor Protein Secretases | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Caspase 3 | Tumor Cells, Cultured | In Situ Nick-End Labeling | Rabbits | Acute Disease | Amyloidosis - enzymology | Amyloidosis - pathology | Neurons - chemistry | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Rats | Brain Diseases - enzymology | Alzheimer Disease - enzymology | Hippocampus - cytology | Enzyme Precursors - analysis | Enzyme Precursors - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Brain Diseases - pathology | Endopeptidases - genetics | Cysteine Proteinase Inhibitors - pharmacology | Neurons - enzymology | Mice | Alzheimer Disease - genetics | Leukemia, Erythroblastic, Acute | Oligopeptides - pharmacology | Camptothecin - pharmacology | Neuropeptides | Research | Cell death | Proteolysis | Nerve proteins
Journal Article