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Nature, ISSN 0028-0836, 03/2019, Volume 567, Issue 7748, pp. 1 - 2
[...]amphotericin B restores the transport of potassium ions in yeast cells that lack a potassium transporter, demonstrating that it can provide a functional... 
Drugs | Membranes | Yeast | Cystic fibrosis | Ions | Lipids | pH effects | Potassium transporter | Respiratory tract | Proteins | Lipid membranes | Amphotericin B | Fibrosis | Transport | Potassium | Transporter
Journal Article
Nature, ISSN 0028-0836, 03/2019, Volume 567, Issue 7748, pp. 315 - 317
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 11/2018, Volume 315, Issue 5, pp. L846 - L857
Ivacaftor is the first drug to target directly defects in the cystic fibrosis transmembrane conductance regulator (CFTR), which causes cystic fibrosis (CF). To... 
CFTR potentiation | Cystic fibrosis | F508del-CFTR | Ivacaftor (VX-770) | CFTR chloride ion channel | MUTANT | PHYSIOLOGY | NUCLEOTIDE-BINDING DOMAINS | MECHANISM | STABILITY | CFTR POTENTIATOR | CHLORIDE-CHANNEL | IN-VITRO | EPITHELIAL-CELLS | RESPIRATORY SYSTEM | cystic fibrosis | ivacaftor (VX-770) | ATP | SMALL-MOLECULE CORRECTORS
Journal Article
The Journal of Physiology, ISSN 0022-3751, 02/2017, Volume 595, Issue 4, pp. 1059 - 1076
Journal Article
Journal of Physiology (London), ISSN 0022-3751, 02/2017, Volume 595, Issue 4, pp. 1059 - 1076
Key points * The cystic fibrosis transmembrane conductance regulator (CFTR), which is defective in the genetic disease cystic fibrosis (CF), forms a gated... 
Journal Article
Journal of Cystic Fibrosis, ISSN 1569-1993, 09/2018, Volume 17, Issue 5, pp. 555 - 557
Journal Article
ISSN 1477-0520, 2/2018, Volume 16, Issue 7, pp. 183 - 187
Ortho -Phenylene bis-ureas serve as anionophores in cells expressing halide-sensitive yellow fluorescent protein, as well as in synthetic vesicles. Activities... 
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 01/2012, Volume 302, Issue 1, pp. C24 - C26
Journal Article
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 04/2016, Volume 47, Issue 4, pp. 484 - 491
Journal Article
Chemical Science, ISSN 2041-6520, 3/2016, Volume 7, Issue 3, pp. 1768 - 1772
Membrane fusion was used to deliver lipophilic synthetic anion transporters to membranes of GUVs and cells, bringing the potential use as a therapeutic or... 
Chemistry
Journal Article
ISSN 2041-6520, 2/2016, Volume 7, Issue 3, pp. 1768 - 1772
Synthetic anion transporters (anionophores) have potential as biomedical research tools and therapeutics. However, the efficient and specific delivery of these... 
Journal Article
Journal of Physiology (London), ISSN 0022-3751, 06/2015, Volume 593, Issue 11, pp. 2427 - 2446
Key points * Malfunction of the cystic fibrosis transmembrane conductance regulator (CFTR), a gated pathway for chloride movement, causes the common... 
Journal Article
American Journal of Physiology, ISSN 0363-6143, 10/2013, Volume 305, Issue 8, p. C817
  The chemical structures of the thyroid hormones triiodothyronine (T3) and thyroxine (T4) resemble those of small-molecules that inhibit the cystic fibrosis... 
Molecules | Membranes | Cystic fibrosis | Thyroid gland | Hormones | Adenosine triphosphatase
Journal Article
2015, RSC drug discovery series, ISBN 1849731861, Volume 39., xviii, 366 pages
Ion channel drug discovery is a rapidly evolving field fuelled by recent, but significant, advances in our understanding of ion channel function combined with... 
Ion channels | Effect of drugs on | Drug development | Drug Discovery | Membrane Transport Modulators | Pharmaceutical chemistry | Other branches of medicine | Chemistry | Canaux ioniques
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