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life sciences & biomedicine (27) 27
science & technology (27) 27
humans (22) 22
cardiovascular system & cardiology (20) 20
aged (18) 18
female (18) 18
male (18) 18
cardiac & cardiovascular systems (17) 17
aspirin (16) 16
stroke (14) 14
risk factors (13) 13
abridged index medicus (12) 12
middle aged (11) 11
rivaroxaban (11) 11
treatment outcome (11) 11
aspirin - adverse effects (10) 10
aspirin - administration & dosage (9) 9
atrial fibrillation (9) 9
double-blind method (9) 9
stroke - prevention & control (9) 9
cardiovascular diseases (8) 8
peripheral vascular disease (8) 8
anticoagulants (7) 7
care and treatment (7) 7
clinical trials (7) 7
hemorrhage - chemically induced (7) 7
atherosclerosis (6) 6
atrial fibrillation - drug therapy (6) 6
bleeding (6) 6
cardiac patients (6) 6
fibrinolytic agents - adverse effects (6) 6
myocardial infarction (6) 6
rivaroxaban - administration & dosage (6) 6
apixaban (5) 5
aspirin - therapeutic use (5) 5
atrial fibrillation - complications (5) 5
factor xa inhibitors - administration & dosage (5) 5
factor xa inhibitors - adverse effects (5) 5
fibrinolytic agents - administration & dosage (5) 5
fibrinolytic agents - therapeutic use (5) 5
heart failure (5) 5
kaplan-meier estimate (5) 5
medicin och hälsovetenskap (5) 5
platelet aggregation inhibitors - administration & dosage (5) 5
prospective studies (5) 5
pyrazoles - adverse effects (5) 5
pyridones - adverse effects (5) 5
risk assessment (5) 5
rivaroxaban - adverse effects (5) 5
stroke - etiology (5) 5
thrombosis (5) 5
time factors (5) 5
anticoagulants - administration & dosage (4) 4
anticoagulants - adverse effects (4) 4
brain ischemia - prevention & control (4) 4
clinical neurology (4) 4
coronary artery disease (4) 4
drug administration schedule (4) 4
drug therapy (4) 4
drug therapy, combination (4) 4
embolism (4) 4
heart attack (4) 4
hemorrhage (4) 4
mortality (4) 4
neurosciences & neurology (4) 4
peripheral arterial disease - drug therapy (4) 4
peripheral artery disease (4) 4
pyrazoles - therapeutic use (4) 4
pyridones - therapeutic use (4) 4
vitamin k (4) 4
aged, 80 and over (3) 3
analysis (3) 3
biological and medical sciences (3) 3
cardiology (3) 3
cardiology and cardiovascular medicine (3) 3
cardiology. vascular system (3) 3
cardiovascular disease (3) 3
cardiovascular diseases - prevention & control (3) 3
coronary artery disease - drug therapy (3) 3
fibrillation (3) 3
follow-up studies (3) 3
health aspects (3) 3
heart (3) 3
heart attacks (3) 3
medical research (3) 3
medical sciences (3) 3
myocardial infarction - therapy (3) 3
neurology (3) 3
platelet aggregation inhibitors - adverse effects (3) 3
proportional hazards models (3) 3
randomized controlled trial (3) 3
thrombectomy (3) 3
thromboembolism - prevention & control (3) 3
[sdv.spee]life sciences [q-bio]/santé publique et épidémiologie (2) 2
administration, oral (2) 2
age (2) 2
age factors (2) 2
anticoagulation (2) 2
atrial fibrillation - diagnosis (2) 2
atrial fibrillation - mortality (2) 2
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1. Full Text Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial
by Diener, Hans-Christoph, Prof, Dr and Eikelboom, John, Prof and Connolly, Stuart J, Prof and Joyner, Campbell D, Prof and Hart, Robert G, Prof and Lip, Gregory YH, Prof and O'Donnell, Martin, MD and Hohnloser, Stefan H, Prof and Hankey, Graeme J, Prof and Shestakovska, Olga, MSc and Yusuf, Salim, Prof and for the AVERROES steering committee and investigators and AVERROES Steering Comm Investigato and AVERROES Steering Committee and Investigators
Lancet neurology, ISSN 1474-4422, 2012, Volume 11, Issue 3, pp. 225 - 231
Neurology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Pyrazoles - therapeutic use | Ischemic Attack, Transient - drug therapy | Atrial Fibrillation - drug therapy | Humans | Middle Aged | Male | Treatment Outcome | Stroke - drug therapy | Fibrinolytic Agents - therapeutic use | Aged, 80 and over | Female | Aged | Aspirin - therapeutic use | Pyridones - therapeutic use | Stroke (Disease) | Care and treatment | Aspirin | Ischemia | Atrial fibrillation | Abnormalities | Clinical trials | Muscle contraction | Index Medicus | Stroke | Fibrillation | Transient ischemic attack | Regression analysis | Age | Bleeding | Embolism | Risk factors | Vitamin K
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2. Full Text Randomized Trial of Primary PCI with or without Routine Manual Thrombectomy
by Jolly, Sanjit S and Cairns, John A and Yusuf, Salim and Meeks, Brandi and Pogue, Janice and Rokoss, Michael J and Kedev, Sasko and Thabane, Lehana and Stankovic, Goran and Moreno, Raul and Gershlick, Anthony and Chowdhary, Saqib and Lavi, Shahar and Niemelä, Kari and Steg, Philippe Gabriel and Bernat, Ivo and Xu, Yawei and Cantor, Warren J and Overgaard, Christopher B and Naber, Christoph K and Cheema, Asim N and Welsh, Robert C and Bertrand, Olivier F and Avezum, Alvaro and Bhindi, Ravinay and Pancholy, Samir and Rao, Sunil V and Natarajan, Madhu K and ten Berg, Jurriën M and Shestakovska, Olga and Gao, Peggy and Widimsky, Petr and Džavík, Vladimír and TOTAL Investigators
The New England journal of medicine, ISSN 0028-4793, 04/2015, Volume 372, Issue 15, pp. 1389 - 1398
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Thrombectomy - adverse effects | Combined Modality Therapy - adverse effects | Coronary Thrombosis - therapy | Myocardial Infarction - complications | Myocardial Infarction - therapy | Stroke - etiology | Coronary Thrombosis - complications | Cardiovascular Diseases - mortality | Electrocardiography | Microvessels | Female | Aged | Heart Failure - etiology | Percutaneous Coronary Intervention - adverse effects | Care and treatment | Usage | Patient outcomes | Cardiac patients | Surgery | Health aspects | Heart attack | Risk factors | Embolism | Myocardial infarction | Cerebral infarction | Medical research | Heart attacks | Heart surgery | Clinical trials | Thrombosis | Evidence-based medicine | Blood clots | Perfusion | Coronary vessels | Implants | Embolization | Death | Microvasculature | Cardiovascular diseases | Heart diseases | Heart failure | Stroke | Funding | Mortality | Catheters | Bailouts | Index Medicus | Abridged Index Medicus
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3. Monitoring Emerging Data From the COMPASS Trial of an Antithrombotic Agent
by Cairns, John A and Eikelboom, John W and Shestakovska, Olga and Yusuf, Salim and DeMets, David
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2019, Volume 73, Issue 21, pp. 2769 - 2772
cardiovascular events | clinical trial stopping guidelines | clinical trials | major bleeding | data monitoring | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiovascular Diseases - prevention & control | Fibrinolytic Agents - therapeutic use | Humans | Aspirin - therapeutic use | Hemorrhage - chemically induced | Drug Therapy, Combination | Rivaroxaban - therapeutic use | Cardiac arrhythmia | Anticoagulants | Stroke | Aspirin | Warfarin | Effectiveness | Hemorrhage | Patients | Bleeding | Embolism | Regulatory approval | Fibrillation | Safety | Acute coronary syndromes | Cardiovascular diseases | Monitoring | Vitamin K
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4. Full Text Design and rationale of the TOTAL trial: A randomized trial of routine aspiration ThrOmbecTomy with percutaneous coronary intervention (PCI) versus PCI ALone in patients with ST-elevation myocardial infarction undergoing primary PCI
by Jolly, Sanjit S., MD, MSc and Cairns, John, MD and Yusuf, Salim, MBBS, DPhil and Meeks, Brandi, MEng and Shestakovska, Olga, MSc and Thabane, Lehana, PhD and Niemelä, Kari, MD, PhD and Steg, Philippe Gabriel, MD and Bertrand, Olivier F., MD, PhD and Rao, Sunil V., MD and Avezum, Alvaro, MD, PhD and Cantor, Warren J., MD and Pancholy, Samir B., MD and Moreno, Raul, MD, PhD and Gershlick, Anthony, MBBS and Bhindi, Ravinay, MBBS, PhD and Welsh, Robert C., MD and Cheema, Asim N., MD, PhD and Lavi, Shahar, MD and Rokoss, Michael, MD and Džavík, Vladimír, MD and TOTAL Investigators
The American heart journal, ISSN 0002-8703, 2014, Volume 167, Issue 3, pp. 315 - 321.e1
Cardiovascular | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Microcirculation | Myocardial Infarction - therapy | Prospective Studies | Percutaneous Coronary Intervention - methods | Humans | Thrombectomy - methods | Treatment Outcome | Combined Modality Therapy | Suction - methods | Transluminal angioplasty | Clinical trials | Care and treatment | Cardiac patients | Heart attack | Heart failure | Enzymes | Stroke | Heart attacks | Medical imaging | Mortality | Thrombosis | Clinical outcomes | Catheters | Blood clots | Hypotheses | Blood pressure | Cardiology | Index Medicus | Abridged Index Medicus
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5. Rivaroxaban Plus Aspirin in Patients With Vascular Disease and Renal Dysfunction From the COMPASS Trial
by Fox, Keith A. A and Eikelboom, John W and Shestakovska, Olga and Connolly, Stuart J and Metsarinne, Kaj P and Yusuf, Salim
Journal of the American College of Cardiology, ISSN 0735-1097, 05/2019, Volume 73, Issue 18, pp. 2243 - 2250
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Correlation of Data | Humans | Middle Aged | Male | Hemorrhage - prevention & control | Renal Insufficiency, Chronic - complications | Peripheral Arterial Disease - complications | Risk Adjustment - methods | Rivaroxaban - administration & dosage | Aspirin - administration & dosage | Fibrinolytic Agents - adverse effects | Rivaroxaban - adverse effects | Aspirin - adverse effects | Female | Renal Insufficiency, Chronic - diagnosis | Myocardial Infarction - etiology | Outcome and Process Assessment, Health Care | Glomerular Filtration Rate | Double-Blind Method | Peripheral Arterial Disease - drug therapy | Coronary Artery Disease - drug therapy | Drug Therapy, Combination - methods | Coronary Artery Disease - complications | Aged | Fibrinolytic Agents - administration & dosage | Myocardial Infarction - prevention & control | Hemorrhage - chemically induced | Myocardial infarction | Anticoagulants | Cerebral infarction | Aspirin | Stroke | Renal function | Heart attacks | Health risks | Cardiovascular disease | Bleeding | Glomerular filtration rate | Confidence intervals | Cost-benefit analysis | Vascular diseases | Ischemia | Coronary vessels | Diuretics | Kidney diseases | Secondary analysis | Nonsteroidal anti-inflammatory drugs | Health risk assessment
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6. Full Text Efficacy and safety of apixaban compared with aspirin in the elderly: A subgroup analysis from the AVERROES trial
by Ng, Kuan H and Shestakovska, Olga and Connolly, Stuart J and Eikelboom, John W and Avezum, Alvaro and Diaz, Rafael and Lanas, Fernando and Yusuf, Salim and Hart, Robert G
Age and ageing, ISSN 0002-0729, 01/2016, Volume 45, Issue 1, pp. 77 - 83
Stroke | Anticoagulation | Elderly | Atrial fibrillation | Age | Apixaban | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Pyrazoles - therapeutic use | Prospective Studies | Age Factors | Humans | Stroke - diagnosis | Male | Time Factors | Aspirin - adverse effects | Atrial Fibrillation - mortality | Aged, 80 and over | Female | Aspirin - therapeutic use | Atrial Fibrillation - diagnosis | Pyrazoles - adverse effects | Stroke - prevention & control | Atrial Fibrillation - drug therapy | Risk Factors | Atrial Fibrillation - complications | Anticoagulants - therapeutic use | Treatment Outcome | Anticoagulants - adverse effects | Atrial Fibrillation - blood | Factor Xa Inhibitors - therapeutic use | Stroke - etiology | Factor Xa Inhibitors - adverse effects | Aged | Pyridones - therapeutic use | Hemorrhage - chemically induced | Pyridones - adverse effects | Care and treatment | Patients | Health aspects | Risk factors | Elderly people | Cardiac arrhythmia | High risk | Clinical trials | Strokes | Antagonists | Acetylsalicylic acid | Hemorrhage | Bleeding | Clinical outcomes | Fibrillation | Older people | Hostility | Safety | Vitamin K | Aspirin | Efficacy | Embolism | Haemorrhage | Geriatrics | Index Medicus
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7. Full Text The CHA2DS2-VASc score identifies those patients with atrial fibrillation and a CHADS2 score of 1 who are unlikely to benefit from oral anticoagulant therapy
by Coppens, Michiel and Eikelboom, John W and Hart, Robert G and Yusuf, Salim and Lip, Gregory Y. H and Dorian, Paul and Shestakovska, Olga and Connolly, Stuart J
European heart journal, ISSN 0195-668X, 2013, Volume 34, Issue 3, pp. 170 - 176
Stroke risk score | Antithrombotic treatment | Atrial fibrillation | Severity of Illness Index | Stroke - prevention & control | Anticoagulants - administration & dosage | Risk Assessment | Administration, Oral | Atrial Fibrillation - drug therapy | Humans | Kaplan-Meier Estimate | Male | Ticlopidine - analogs & derivatives | Aspirin - administration & dosage | Thromboembolism - prevention & control | Platelet Aggregation Inhibitors - administration & dosage | Brain Ischemia - diagnosis | Ticlopidine - administration & dosage | Female | Aged | Fibrinolytic Agents - administration & dosage | Drug Therapy, Combination | Index Medicus
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8. Full Text Risk of ischaemic stroke according to pattern of atrial fibrillation: analysis of 6563 aspirin-treated patients in ACTIVE-A and AVERROES
by Vanassche, Thomas and Vanassche, Thomas and Lauw, Mandy N and Lauw, Mandy N and Eikelboom, John W and Eikelboom, John W and Healey, Jeff S and Healey, Jeff S and Hart, Robert G and Hart, Robert G and Alings, Marco and Alings, Marco and Avezum, Alvaro and Avezum, Alvaro and Díaz, Rafael and Díaz, Rafael and Hohnloser, Stefan H and Hohnloser, Stefan H and Lewis, Basil S and Lewis, Basil S and Shestakovska, Olga and Shestakovska, Olga and Wang, Jia and Wang, Jia and Connolly, Stuart J and Connolly, Stuart J
European heart journal, ISSN 0195-668X, 02/2015, Volume 36, Issue 5, pp. 7 - 287
Stroke | Paroxysmal | Permanent | Atrial fibrillation | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Stroke - prevention & control | Embolism - prevention & control | Double-Blind Method | Humans | Risk Factors | Atrial Fibrillation - complications | Kaplan-Meier Estimate | Male | Brain Ischemia - prevention & control | Brain Ischemia - etiology | Stroke - etiology | Fibrinolytic Agents - therapeutic use | Sex Distribution | Female | Aged | Aspirin - therapeutic use | Embolism - etiology | Index Medicus
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9. Full Text Major Bleeding in Patients With Coronary or Peripheral Artery Disease Treated With Rivaroxaban Plus Aspirin
by Eikelboom, John W and Bosch, Jacqueline J and Connolly, Stuart J and Shestakovska, Olga and Dagenais, Gilles R and Hart, Robert G and Leong, Darryl P and O’Donnell, Martin and Fox, Keith A.A and Bhatt, Deepak L and Cairns, John A and Tasto, Christoph and Berkowitz, Scott D and Cook Bruns, Nancy and Muehlhofer, Eva and Diaz, Rafael and Maggioni, Aldo P and Yusuf, Salim
Journal of the American College of Cardiology, ISSN 0735-1097, 09/2019, Volume 74, Issue 12, pp. 1519 - 1528
coronary artery disease | dual pathway | aspirin | rivaroxaban | bleeding | peripheral artery disease | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Severity of Illness Index | Humans | Male | Peripheral Arterial Disease - complications | Rivaroxaban - administration & dosage | Aspirin - administration & dosage | Factor Xa Inhibitors - administration & dosage | Rivaroxaban - adverse effects | Aspirin - adverse effects | Coronary Artery Disease - complications | Factor Xa Inhibitors - adverse effects | Platelet Aggregation Inhibitors - administration & dosage | Female | Aged | Hemorrhage - chemically induced | Drug Combinations | Platelet Aggregation Inhibitors - adverse effects | Anticoagulants | Aspirin | Stroke | Transfusion | Mortality | Cardiovascular disease | Gastrointestinal tract | Thrombosis | Bleeding | Clotting | Randomization | Vascular diseases | Hemostasis | Rectum | Hemoglobin | Hemostatics | Thromboembolism | Cardiovascular diseases | Platelets
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10. Full Text Rivaroxaban Plus Aspirin in Patients With Vascular Disease and Renal Dysfunction
by Fox, Keith A.A and Eikelboom, John W and Shestakovska, Olga and Connolly, Stuart J and Metsarinne, Kaj P and Yusuf, Salim
Journal of the American College of Cardiology, ISSN 0735-1097, 05/2019, Volume 73, Issue 18, pp. 2243 - 2250
atherosclerosis | aspirin | rivaroxaban | death | stroke | myocardial infarction
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11. Full Text Efficacy and safety of apixaban compared with aspirin in patients who previously tried but failed treatment with vitamin K antagonists: results from the AVERROES trial
by Coppens, Michiel and Synhorst, David and Eikelboom, John W and Yusuf, Salim and Shestakovska, Olga and Connolly, Stuart J
European heart journal, ISSN 0195-668X, 2014, Volume 35, Issue 28, pp. 1856 - 1863
Aspirin | Stroke | Atrial fibrillation | Vitamin K antagonists | Bleeding | Apixaban | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Stroke - prevention & control | Double-Blind Method | Drug Administration Schedule | Humans | Risk Factors | Atrial Fibrillation - complications | Male | Treatment Outcome | Aspirin - administration & dosage | Factor Xa Inhibitors - administration & dosage | Fibrinolytic Agents - adverse effects | Pyridones - administration & dosage | Pyrazoles - administration & dosage | Vitamin K - antagonists & inhibitors | Aspirin - adverse effects | Factor Xa Inhibitors - adverse effects | Female | Aged | Fibrinolytic Agents - administration & dosage | Hemorrhage - chemically induced | Pyridones - adverse effects | Pyrazoles - adverse effects | Index Medicus
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12. Full Text Oral factor Xa inhibitors and risk of subdural hematoma: COMPASS trial results and meta-analysis
by Catanese, Luciana and Eikelboom, John W and Bosch, Jackie and Shestakovska, Olga and Ng, Kelvin and Nayar, Sumiti and Perera, Kanjana S and Shoamanesh, Ashkan and Sharma, Mukul and Hart, Robert G
Neurology, ISSN 0028-3878, 08/2020, Volume 95, Issue 5, pp. e480 - e487
Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Index Medicus | Abridged Index Medicus
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13. Full Text Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin
by Moayyedi, Paul and Eikelboom, John W and Bosch, Jackie and Connolly, Stuart J and Dyal, Leanne and Shestakovska, Olga and Leong, Darryl and Anand, Sonia S and Störk, Stefan and Branch, Kelley R.H and Bhatt, Deepak L and Verhamme, Peter B and O’Donnell, Martin and Maggioni, Aldo P and Lonn, Eva M and Piegas, Leopoldo S and Ertl, Georg and Keltai, Matyas and Bruns, Nancy Cook and Muehlhofer, Eva and Dagenais, Gilles R and Kim, Jae-Hyung and Hori, Masatsugu and Steg, P. Gabriel and Hart, Robert G and Diaz, Rafael and Alings, Marco and Widimsky, Petr and Avezum, Alvaro and Probstfield, Jeffrey and Zhu, Jun and Liang, Yan and Lopez-Jaramillo, Patricio and Kakkar, Ajay K and Parkhomenko, Alexander N and Ryden, Lars and Pogosova, Nana and Dans, Antonio L and Lanas, Fernando and Commerford, Patrick J and Torp-Pedersen, Christian and Guzik, Tomek J and Vinereanu, Dragos and Tonkin, Andrew M and Lewis, Basil S and Felix, Camilo and Yusoff, Khalid and Metsarinne, Kaj P and Fox, Keith A.A and Yusuf, Salim and COMPASS Investigators
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 09/2019, Volume 157, Issue 3, pp. 682 - 691.e2
Reflux | CVD | Bacteria | Thrombosis | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Prospective Studies | Cardiovascular Diseases - drug therapy | Humans | Middle Aged | Male | Enterocolitis, Pseudomembranous - microbiology | Pantoprazole - administration & dosage | Rivaroxaban - administration & dosage | Aspirin - administration & dosage | Factor Xa Inhibitors - administration & dosage | Enterocolitis, Pseudomembranous - chemically induced | Rivaroxaban - adverse effects | Proton Pump Inhibitors - administration & dosage | Time Factors | Aspirin - adverse effects | Platelet Aggregation Inhibitors - administration & dosage | Female | Cardiovascular Diseases - diagnosis | Platelet Aggregation Inhibitors - adverse effects | Proton Pump Inhibitors - adverse effects | Double-Blind Method | Drug Administration Schedule | Risk Assessment | Risk Factors | Peripheral Arterial Disease - drug therapy | Treatment Outcome | Gastrointestinal Hemorrhage - chemically induced | Gastrointestinal Hemorrhage - prevention & control | Peripheral Arterial Disease - diagnosis | Factor Xa Inhibitors - adverse effects | Pantoprazole - adverse effects | Aged | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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