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Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2016, Volume 354, Issue 6312, pp. 618 - 622
Tobacco smoking increases the risk of at least 17 classes of human cancer. We analyzed somatic mutations and DNA methylation in 5243 cancers of types for which... 
LUNG-CANCER | HUMAN TISSUES | LANDSCAPE | GENOMES | DNA | MULTIDISCIPLINARY SCIENCES | CARCINOGENS | PATTERNS | HOTSPOTS | EXPOSURE | PROTEIN ADDUCTS | Tobacco | Mutation | Smoking | Cancer | Mutations | Deoxyribonucleic acid | Risk | Smoke | Signatures | BASIC BIOLOGICAL SCIENCES | Biological Science | 60 APPLIED LIFE SCIENCES
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2008, Volume 105, Issue 36, pp. 13568 - 13573
...Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy Tatsuhiro Shibata* † , Tsutomu Ohta ‡ , Kit I. Tong... 
Tumor cell line | Oxidative stress | Genes | Cell lines | Small interfering RNA | Gene expression regulation | Genetic mutation | Cancer | Tumors | Lung neoplasms | Somatic mutation | Cancer cell microenvironment | Ubiquitin-proteasome system | Multidrug resistant-associated protein | multidrug resistant-associated protein | PROTEIN | EFFICACY | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | HYPOXIA | ubiquitin-proteasome system | CARCINOGENESIS | POLYMORPHISMS | GENE | ADAPTER | somatic mutation | cancer cell microenvironment | BINDING | oxidative stress | Neoplasms - metabolism | Protein Structure, Tertiary | Oxidative Stress | Humans | Models, Molecular | Substrate Specificity | Intracellular Signaling Peptides and Proteins - metabolism | Down-Regulation - drug effects | Mutation - genetics | Neoplasms - genetics | Base Sequence | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | Cullin Proteins - metabolism | Protein Binding | NF-E2-Related Factor 2 - genetics | Antineoplastic Agents - pharmacology | Active Transport, Cell Nucleus | Gene Expression Regulation, Neoplastic - drug effects | NF-E2-Related Factor 2 - chemistry | Transcription, Genetic - genetics | Kelch-Like ECH-Associated Protein 1 | Genetic aspects | Genetic transcription | Research | Gene mutations | Health aspects | Biological Sciences
Journal Article
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 13616
Journal Article
by Alexandrov, Ludmil B and Nik-Zainal, Serena and Wedge, David C and Aparicio, Samuel A. J. R and Behjati, Sam and Biankin, Andrew V and Bignell, Graham R and Bolli, Niccolò and Borg, Ake and Børresen-Dale, Anne-Lise and Boyault, Sandrine and Burkhardt, Birgit and Butler, Adam P and Caldas, Carlos and Davies, Helen R and Desmedt, Christine and Eils, Roland and Eyfjörd, Jórunn Erla and Foekens, John A and Greaves, Mel and Hosoda, Fumie and Hutter, Barbara and Ilicic, Tomislav and Imbeaud, Sandrine and Imielinski, Marcin and Jäger, Natalie and Jones, David T. W and Jones, David and Knappskog, Stian and Kool, Marcel and Lakhani, Sunil R and López-Otín, Carlos and Martin, Sancha and Munshi, Nikhil C and Nakamura, Hiromi and Northcott, Paul A and Pajic, Marina and Papaemmanuil, Elli and Paradiso, Angelo and Pearson, John V and Puente, Xose S and Raine, Keiran and Ramakrishna, Manasa and Richardson, Andrea L and Richter, Julia and Rosenstiel, Philip and Schlesner, Matthias and Schumacher, Ton N and Span, Paul N and Teague, Jon W and Totoki, Yasushi and Tutt, Andrew N. J and Valdés-Mas, Rafael and van Buuren, Marit M and van ’t Veer, Laura and Vincent-Salomon, Anne and Waddell, Nicola and Yates, Lucy R and Zucman-Rossi, Jessica and Andrew Futreal, P and McDermott, Ultan and Lichter, Peter and Meyerson, Matthew and Grimmond, Sean M and Siebert, Reiner and Campo, Elías and Shibata, Tatsuhiro and Pfister, Stefan M and Campbell, Peter J and Stratton, Michael R and ICGC MMML-Seq Consortium and ICGC PedBrain and ICGC Breast Cancer Consortium and Australian Pancreatic Cancer Genome Initiative and ICGC Breast Canc Consortium and Australian Pancreatic Canc Genome
Nature (London), ISSN 1476-4687, 2013, Volume 500, Issue 7463, pp. 415 - 421
Journal Article
Nature medicine, ISSN 1546-170X, 2012, Volume 18, Issue 3, pp. 375 - 377
Journal Article
Cancer science, ISSN 1347-9032, 2018, Volume 109, Issue 2, pp. 446 - 452
Journal Article
Breast cancer research and treatment, ISSN 1573-7217, 2011, Volume 132, Issue 3, pp. 793 - 805
Journal Article