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Clinical and Experimental Nephrology, ISSN 1342-1751, 6/2018, Volume 22, Issue 3, pp. 702 - 709
Journal Article
by Okada, Yukinori and Wu, Di and Trynka, Gosia and Raj, Towfique and Terao, Chikashi and Ikari, Katsunori and Kochi, Yuta and Ohmura, Koichiro and Suzuki, Akari and Yoshida, Shinji and Graham, Robert R and Manoharan, Arun and Ortmann, Ward and Bhangale, Tushar and Denny, Joshua C and Carroll, Robert J and Eyler, Anne E and Greenberg, Jeffrey D and Kremer, Joel M and Pappas, Dimitrios A and Jiang, Lei and Yin, Jian and Ye, Lingying and Su, Ding-Feng and Yang, Jian and Xie, Gang and Keystone, Ed and Westra, Harm-Jan and Esko, Tõnu and Metspalu, Anes and Zhou, Xuezhong and Gupta, Namrata and Mirel, Daniel and Stahl, Eli A and Diogo, Dorothée and Cui, Jing and Liao, Katherine and Guo, Michael H and Myouzen, Keiko and Kawaguchi, Takahisa and Coenen, Marieke J. H and van Riel, Piet L. C. M and van de Laar, Mart A. F. J and Guchelaar, Henk-Jan and Huizinga, Tom W. J and Dieudé, Philippe and Mariette, Xavier and Bridges, S. Louis and Zhernakova, Alexana and Toes, Rene E. M and Tak, Paul P and Miceli-Richard, Corinne and Bang, So-Young and Lee, Hye-Soon and Martin, Javier and Gonzalez-Gay, Miguel A and Roiguez-Roiguez, Luis and Rantapää-Dahlqvist, Solbritt and Arlestig, Lisbeth and Choi, Hyon K and Kamatani, Yoichiro and Galan, Pilar and Lathrop, Mark and Eyre, Steve and Bowes, John and Barton, Anne and de Vries, Niek and Moreland, Larry W and Criswell, Lindsey A and Karlson, Elizabeth W and Taniguchi, Atsuo and Yamada, Ryo and Kubo, Michiaki and Liu, Jun S and Bae, Sang-Cheol and Worthington, Jane and Padyukov, Leonid and Klareskog, Lars and Gregersen, Peter K and Raychaudhuri, Soumya and Stranger, Barbara E and de Jager, Philip L and Franke, Lude and Visscher, Peter M and Brown, Matthew A and Yamanaka, Hisashi and Mimori, Tsuneyo and Takahashi, Atsushi and Xu, Huji and Behrens, Timothy W and Siminovitch, Katherine A and Momohara, Shigeki and Matsuda, Fumihiko and Yamamoto, Kazuhiko and Plenge, Robert M and Lee, Annette and Martin, Paul and Stahl, Eli and Viatte, Sebastien and McAllister, Kate and ... and RACI Consortium and GARNET Consortium and RACI consortium and GARNET consortium and the RACI consortium and the GARNET consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Reumatologi
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 376 - +
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated variants with diverse genomic and biological data sets... 
RECEPTOR INHIBITION | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY | RISK | LOCI | IDENTIFICATION | TRAITS | GENOME-WIDE ASSOCIATION | RESOURCE | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Humans | Asian Continental Ancestry Group - genetics | Computational Biology | Male | Drug Repositioning | Molecular Targeted Therapy | Drug Discovery | Case-Control Studies | Arthritis, Rheumatoid - pathology | Mice, Knockout | Arthritis, Rheumatoid - metabolism | Arthritis, Rheumatoid - genetics | Animals | Arthritis, Rheumatoid - drug therapy | Alleles | Polymorphism, Single Nucleotide - genetics | Female | Hematologic Neoplasms - genetics | Mice | Hematologic Neoplasms - metabolism | Quantitative trait loci | Genome-wide association studies | Rheumatoid arthritis | Genetic research | Genetic aspects | Research | Human genetics | Disease | Hematology | Cytokines | Genes | Genomics | Genomes | Meta-analysis | Proteins | Confidence intervals | Hypotheses | Quality control | Epigenetics | Population | Genetics | Health risk assessment | Asians | Cancer | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Virtual screening | Klinisk medicin
Journal Article
by Kajimoto, Katsuya and Minami, Yuichiro and Otsubo, Shigeru and Sato, Yukihito and Sato, Takatoshi and Sato, Takamasa and Sato, Naoki and Asai, Kuniya and Munakata, Ryo and Aokage, Toshiyuki and Yoshida, Asuka and Yoshida, Daisuke and Yoshida, Kentaro and Yumino, Dai and Mizuno, Kiyo-o and Mizuno, Masayuki and Kawada, Erisa and Ozaki, Yuri and Kogure, Tomohito and Haruki, Shintaro and Nakao, Koichi and Sawamura, Tadashi and Sawamura, Akinori and Nuki, Toshiaki and Ishiki, Ryoji and Yokota, Yuya and Yokota, Shigeki and Fujinaga, Hiroyuki and Yamamoto, Takashi and Harada, Kenji and Saito, Taro and Saito, Akihiro and Kageyama, Norihito and Okumura, Takanobu and Hata, Noritake and Murai, Koji and Nozaki, Ayaka and Kawanaka, Hidekazu and Tanabe, Jun and Ishii, Katsuhisa and Oiwa, Hitoshi and Matsumoto, Tomoaki and Kato, Hiromasa and Kato, Nobuo and Kato, Masahiko and Suzuki, Hiroshi and Shimizu, Nobuyuki and Shimizu, Hayato and Keida, Takehiko and Fujita, Takashi and Fujita, Masaki and Nakamura, Keita and Nakamura, Makiko and Nakamura, Kentaro and Chinen, Toshiya and Meguro, Kentaro and Kikuchi, Tatsuro and Nishikido, Toshiyuki and Nakata, Masaya and Nakata, Marohito and Yamashita, Shizuya and Yamashita, Eiji and Yamashita, Tatsuya and Hirono, Akitoshi and Mitsudo, Kazuaki and Kadota, Kazushige and Makita, Noriko and Watanabe, Nagisa and Kawabata, Masaaki and Fujii, Kenichi and Fujii, Shinya and Okuda, Shinichi and Kobayashi, Hiroshi and Kobayashi, Shigeki and Moriuchi, Ikuo and Osato, Kazuo and Murakami, Tatsuaki and Shimada, Yoshifumi and Shimada, Katsunori and Misawa, Katsushi and Kokado, Hiromasa and Fukuoka, Yoshitomo and Takabatake, Syu and Takata, Yoshifumi and Miyagi, Manabu and Tanaka, Nobuhiro and Yamashina, Akira and Sudo, Shinji and Shimamura, Koichi and Nagashima, Michitaka and Kaneda, Tomoya and Ueda, Yasunori and Ueda, Kosei and Higashikata, Toshinori and Fujimori, Kanichi and Yagi, Masahiro and Takaki, Jyunko and Toyama, Takuji and Hirata, Tetsuo and Kamisihima, Kazuho and ... and Acute Decompensated Heart Failure and investigators of the Acute Decompensated Heart Failure Syndromes (ATTEND) registry
The American Journal of Cardiology, ISSN 0002-9149, 09/2017, Volume 120, Issue 5, pp. 809 - 816
The aim of this study was to evaluate the association of functional mitral regurgitation (FMR), preserved or reduced ejection fraction (EF), and ischemic or... 
VENTRICULAR SYSTOLIC DYSFUNCTION | PROGNOSTIC IMPLICATIONS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | DETERMINANTS | DISEASE | RISK | DILATED CARDIOMYOPATHY | ECHOCARDIOGRAPHY | QUANTITATIVE DOPPLER ASSESSMENT | SEVERITY | Japan - epidemiology | Prospective Studies | Humans | Heart Failure - physiopathology | Male | Mitral Valve Insufficiency - epidemiology | Heart Ventricles - diagnostic imaging | Incidence | Echocardiography, Doppler | Myocardial Ischemia - physiopathology | Female | Registries | Ventricular Function, Left - physiology | Myocardial Ischemia - diagnosis | Heart Failure - mortality | Severity of Illness Index | Heart Failure - complications | Acute Disease | Survival Rate - trends | Stroke Volume - physiology | Mitral Valve Insufficiency - diagnosis | Heart Ventricles - physiopathology | Myocardial Ischemia - complications | Cause of Death - trends | Mitral Valve Insufficiency - etiology | Heart failure | Care and treatment | Mitral valve insufficiency | Patient outcomes | Analysis | Cardiac patients | Hypertension | Heart attacks | Cardiomyopathy | Mortality | Color | Disorders | Cardiovascular disease | Hospitalization | Patients | Discharge | Confidence intervals | Ultrasonic imaging | Ischemia | Regurgitation | Acute coronary syndromes | Health risk assessment | Heart diseases | Failure | Ejection
Journal Article
Nature Genetics, ISSN 1061-4036, 05/2012, Volume 44, Issue 5, pp. 511 - 516
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, pp. e0120143 - e0120143
Background The relevance of lysophosphatidylcholine acyltransferase1 (LPCAT1), a cytosolic enzyme in the remodeling pathway of phosphatidylcholine metabolism,... 
FACTOR-RECEPTOR | METASTASIS | FACTOR PAF | 1 LPCAT1 | MULTIDISCIPLINARY SCIENCES | GROWTH | FACTOR-KAPPA-B | PROLIFERATION | ACYL-COA | EXPRESSION | CANCER | Up-Regulation | Cell Proliferation | Receptors, G-Protein-Coupled - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Gene Expression Regulation, Neoplastic | Mouth Neoplasms - metabolism | Gene Knockdown Techniques | Neoplasm Invasiveness - pathology | Platelet Membrane Glycoproteins - metabolism | Tumor Cells, Cultured | Mouth Neoplasms - genetics | 1-Acylglycerophosphocholine O-Acyltransferase - genetics | RNA, Messenger - genetics | Mouth - metabolism | Platelet Membrane Glycoproteins - genetics | Platelet Activating Factor - metabolism | Cell Line, Tumor | Mouth - pathology | Mouth Neoplasms - pathology | Receptors, G-Protein-Coupled - genetics | Neoplasm Invasiveness - genetics | 1-Acylglycerophosphocholine O-Acyltransferase - metabolism | Immunohistochemistry | Enzymes | Squamous cell carcinoma | RNA | Analysis | Biosynthesis | Phospholipids | Chemical properties | Cell proliferation | Cell culture | Biotechnology | Correlation | Leukocyte migration | Lecithin | Laboratories | Platelet-activating factor | Science | mRNA | Metastasis | Kinases | Lymph nodes | Lysophosphatidylcholine | Cell adhesion & migration | Maxillofacial surgery | Metastases | Proteins | Liver cancer | Ethics | Angiogenesis | Rodents | Surgery | Penicillin | Down-regulation | Invasiveness | Melanoma | Keratinocytes | Inflammation | Functional analysis | Oral squamous cell carcinoma | Dentistry | Gene expression | Metabolism | Medicine | Chemotherapy | Cell lines | Prostate | Cell migration | Cancer | Index Medicus
Journal Article