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1. Full Text Brachiocephalic Vein Thrombosis
by Hirosawa, Takanobu and Shimizu, Taro
The American journal of the medical sciences, ISSN 0002-9629, 05/2020, Volume 359, Issue 5, pp. 306 - 307
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2. Osmotic demyelination syndrome due to hyperosmolar hyperglycemia
by Hirosawa, Takanobu and Shimizu, Taro
Cleveland Clinic journal of medicine, ISSN 0891-1150, 07/2018, Volume 85, Issue 7, pp. 511 - 513
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Brain - diagnostic imaging | Humans | Middle Aged | Hyperglycemia - complications | Blood Glucose | Male | Hyperglycemic Hyperosmolar Nonketotic Coma - complications | Magnetic Resonance Imaging | Demyelinating Diseases - diagnosis | Fluid Therapy - methods | Brain - pathology | Demyelinating Diseases - etiology | Diabetes Mellitus, Type 2 - complications | Insulin - therapeutic use
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3. Full Text Gastric Anisakiasis
by Hirosawa, Takanobu and Sakamoto, Tetsu and Shimizu, Taro
The American journal of the medical sciences, ISSN 0002-9629, 09/2020, Volume 360, Issue 3, pp. 318 - 319
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology
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4. Full Text SAPHO Syndrome
by Hirosawa, Takanobu and Katsukura, Shinichi and Shimizu, Taro
The American journal of the medical sciences, ISSN 0002-9629, 01/2020, Volume 359, Issue 1, pp. e5 - e6
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Acquired Hyperostosis Syndrome - diagnosis | Acquired Hyperostosis Syndrome - drug therapy | Humans | Middle Aged | Acquired Hyperostosis Syndrome - pathology | Male | Methotrexate - therapeutic use | Antirheumatic Agents - therapeutic use | Myocardial Ischemia - pathology
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5. Full Text microRNA Modulation of Circadian-Clock Period and Entrainment
by Cheng, Hai-Ying M and Papp, Joseph W and Varlamova, Olga and Dziema, Heather and Russell, Brandon and Curfman, John P and Nakazawa, Takanobu and Shimizu, Kimiko and Okamura, Hitoshi and Impey, Soren and Obrietan, Karl
Neuron (Cambridge, Mass.), ISSN 0896-6273, 06/2007, Volume 54, Issue 5, pp. 813 - 829
SYSNEURO | MOLNEURO | SIGNALING | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Humans | Up-Regulation - radiation effects | Suprachiasmatic Nucleus - radiation effects | MAP Kinase Signaling System - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Biological Clocks - radiation effects | Trans-Activators - genetics | Suprachiasmatic Nucleus - metabolism | Circadian Rhythm - radiation effects | Brain Chemistry - genetics | ARNTL Transcription Factors | Cell Line | MAP Kinase Signaling System - radiation effects | Basic Helix-Loop-Helix Transcription Factors - genetics | Gene Expression Regulation - genetics | Circadian Rhythm - genetics | Up-Regulation - genetics | Photoperiod | Suprachiasmatic Nucleus - anatomy & histology | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | CLOCK Proteins | Biological Clocks - genetics | Gene Expression Regulation - radiation effects | Trans-Activators - metabolism | Mice | MicroRNAs - genetics | Photic Stimulation | Proteins | Transcription factors | Polypeptides | Dehydrogenases | Light | Circadian rhythm | Kinases | Gene expression | Questioning | Index Medicus
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6. Full Text Esterified carotenoids are synthesized in petals of carnation (Dianthus caryophyllus) and accumulate in differentiated chromoplasts
by Iijima, Luna and Kishimoto, Sanae and Ohmiya, Akemi and Yagi, Masafumi and Okamoto, Emi and Miyahara, Taira and Tsujimoto, Takashi and Ozeki, Yoshihiro and Uchiyama, Nahoko and Hakamatsuka, Takashi and Kouno, Takanobu and Cano, Emilio A and Shimizu, Motoki and Nishihara, Masahiro
Scientific reports, ISSN 2045-2322, 12/2020, Volume 10, Issue 1, pp. 15256 - 15256
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Dianthus - genetics | Flowers - metabolism | Biosynthetic Pathways | Gene Expression Profiling | Esterification | Flowers - growth & development | Dianthus - growth & development | Dianthus - metabolism | Plant Proteins - genetics | Sequence Analysis, RNA | Carotenoids - metabolism | Gene Expression Regulation, Plant | Plastids - genetics | Plastids - metabolism | Carotenoids - chemistry | Flowers - genetics | Petals | Carotenoids | Xanthophyll | Biosynthesis | Flowers & plants | Flowers | Ribonucleic acid--RNA | Chromatophores | Cultivars | Index Medicus
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7. Full Text Cerebral Venous Thrombosis
by Hirosawa, Takanobu and Shiinoki, Makiko and Shimizu, Taro
The American journal of the medical sciences, ISSN 0002-9629, 07/2019, Volume 358, Issue 1, pp. e3 - e3
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Intracranial Thrombosis - complications | Headache - etiology | Anticoagulants - administration & dosage | Venous Thrombosis - drug therapy | Humans | Heparin - administration & dosage | Magnetic Resonance Angiography | Venous Thrombosis - diagnostic imaging | Anticoagulants - therapeutic use | Heparin - therapeutic use | Male | Treatment Outcome | Venous Thrombosis - complications | Cerebral Angiography | Cerebral Veins - diagnostic imaging | Headache - diagnostic imaging | Vomiting - etiology | Adult | Intracranial Thrombosis - drug therapy | Intracranial Thrombosis - diagnostic imaging
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8. Full Text Metoclopramide-induced Serotonin Syndrome
by Harada, Taku and Hirosawa, Takanobu and Morinaga, Kouhei and Shimizu, Taro
Internal medicine (Tokyo, 1992), ISSN 0918-2918, 2017, Volume 56, Issue 6, pp. 737 - 739
serotonin syndrome | metocloplamide | Metocloplamide | Serotonin syndrome | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Serotonin Uptake Inhibitors - pharmacokinetics | Mianserin - pharmacokinetics | Humans | Mianserin - therapeutic use | Serotonin Uptake Inhibitors - therapeutic use | Bipolar Disorder - drug therapy | Mianserin - analogs & derivatives | Serotonin Syndrome - chemically induced | Drug Interactions | Metoclopramide - pharmacology | Adult | Female | Antiemetics - pharmacology | Signs and symptoms | Cyproheptadine | Serotonin | Myoclonus | Antidepressants | Muscles | Bipolar disorder | Lorazepam | Rigidity | Metoclopramide | Index Medicus | Case Report
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9. Full Text Eosinopenia as a diagnostic marker of bloodstream infection in a general internal medicine setting: a cohort study
by Hirosawa, Takanobu and Harada, Yukinori and Morinaga, Kohei and Takase, Hiroshi and Nin, Michihiro and Shimizu, Taro
BMC infectious diseases, ISSN 1471-2334, 01/2020, Volume 20, Issue 1, pp. 85 - 85
Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Eosinophils - metabolism | Data Accuracy | Area Under Curve | Agranulocytosis | Humans | Japan | Middle Aged | Hospitals, University | Logistic Models | Male | Bacteremia - diagnosis | Biomarkers - blood | Sensitivity and Specificity | Aged, 80 and over | Bacteremia - blood | Adult | Female | Aged | Retrospective Studies | Leukocyte Count - methods | Neutrophils - metabolism | Prognosis | Diagnosis | Septicemia | Eosinophil disorders | Granulocytopenia | Cell culture | Therapy | C-reactive protein | Infections | Blood | Confidence intervals | Variables | Regression models | Reliability analysis | Blood pressure | Blood culture | Significance | Culture | Age | Automation | Statistical analysis | Hematology | Internal medicine | Markers | Neutrophils | Regression analysis | Patients | Reclassification | Medicine | Studies | Antibiotics | Eosinopenia | Sepsis | Diagnostic systems | Steroids | Index Medicus | Bloodstream infection
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10. Full Text Thalidomide maintenance therapy in Japanese myeloma patients: a multicenter, phase II clinical trial (COMET study)
by Murakami, Hirokazu and Kasamatsu, Tetsuhiro and Murakami, Jun and Kiguchi, Toru and Kanematsu, Takeshi and Ogawa, Daisuke and Takamatsu, Hiroyuki and Handa, Hiroshi and Ozaki, Shuji and Miki, Hirokazu and Takahashi, Takeshi and Takeo, Takaaki and Yamauchi, Tatsuya and Morishita, Takanobu and Kosugi, Hiroshi and Shimizu, Kazuyuki
International journal of hematology, ISSN 0925-5710, 4/2019, Volume 109, Issue 4, pp. 409 - 417
Medicine & Public Health | Hematology | Adverse events | Multiple myeloma | Oncology | Efficacy | Maintenance | Thalidomide | Life Sciences & Biomedicine | Science & Technology | Medicine, Experimental | Clinical trials | Medical research | Product development | Therapy | Patients | Index Medicus
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11. Full Text SAPHO syndrome
by Hirosawa, Takanobu and Kawamoto, Shun and Shimizu, Taro
BMJ case reports, ISSN 1757-790X, 12/2019, Volume 12, Issue 12, p. e233221
Sternoclavicular Joint - diagnostic imaging | Diagnosis, Differential | Psoriasis - drug therapy | Sternoclavicular Joint - pathology | Acquired Hyperostosis Syndrome - drug therapy | Acquired Hyperostosis Syndrome - diagnostic imaging | Chest Pain | Humans | Middle Aged | Sternoclavicular Joint - drug effects | Male | Antirheumatic Agents - therapeutic use | Drugs | Pain | Bone diseases | Dermatitis | Inflammatory diseases | Index Medicus
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12. Full Text A nationwide survey of hepatitis E virus (HEV) infection in wild boars in Japan: identification of boar HEV strains of genotypes 3 and 4 and unrecognized genotypes
by Sato, Yukihiro and Sato, Hiroyuki and Naka, Keisuke and Furuya, Satoshi and Tsukiji, Haruhisa and Kitagawa, Koji and Sonoda, Yoshihide and Usui, Takanobu and Sakamoto, Hirotsugu and Yoshino, Sumi and Shimizu, Yuko and Takahashi, Masaharu and Nagashima, Shigeo and Jirintai and Nishizawa, Tsutomu and Okamoto, Hiroaki
Archives of virology, ISSN 0304-8608, 8/2011, Volume 156, Issue 8, pp. 1345 - 1358
Medical Microbiology | Infectious Diseases | Biomedicine | Virology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Miscellaneous | Viral hepatitis | Infectious diseases | Microbiology | Viral diseases | Biological and medical sciences | Medical sciences | Human viral diseases | Liver - virology | Japan - epidemiology | Prevalence | Humans | Genotype | Hepatitis E - virology | RNA, Viral - blood | Hepatitis E virus - genetics | Phylogeny | Antibodies, Viral - blood | Hepatitis E - epidemiology | Disease Reservoirs - veterinary | Animals | Hepatitis E virus - classification | Hepatitis E - veterinary | Sus scrofa | Medical colleges | Hepatitis E | RNA | Immunoglobulin G | Reservoirs | Genetic aspects | Health aspects | Index Medicus
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13. Full Text The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation
by Shimizu, Takanobu and Nakamura, Takeshi and Inaba, Hironori and Iwasa, Hiroaki and Maruyama, Junichi and Arimoto-Matsuzaki, Kyoko and Nakata, Takao and Nishina, Hiroshi and Hata, Yutaka
The Journal of biological chemistry, ISSN 0021-9258, 08/2020, Volume 295, Issue 32, pp. 11214 - 11230
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Index Medicus
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14. Full Text UNC119 is a binding partner of tumor suppressor Ras‐association domain family 6 and induces apoptosis and cell cycle arrest by MDM2 and p53
by Iwasa, Hiroaki and Sarkar, Aradhan and Shimizu, Takanobu and Sawada, Takeru and Hossain, Shakhawoat and Xu, Xiaoyin and Maruyama, Junichi and Arimoto‐Matsuzaki, Kyoko and Withanage, Kanchanamala and Nakagawa, Kentaro and Kurihara, Hidetake and Kuroyanagi, Hidehito and Hata, Yutaka
Cancer science, ISSN 1347-9032, 09/2018, Volume 109, Issue 9, pp. 2767 - 2780
MDM2 | apoptosis | tumor suppressor | RASSF | p53 | Life Sciences & Biomedicine | Oncology | Science & Technology | Polyploidy | Tumor Suppressor Proteins - metabolism | HCT116 Cells | Humans | Tumor Suppressor Protein p53 - metabolism | DNA Repair - genetics | Tumor Suppressor Protein p53 - genetics | Cell Cycle Checkpoints | Monomeric GTP-Binding Proteins - metabolism | Neoplasms - genetics | HEK293 Cells | Cell Line, Tumor | DNA Damage - genetics | Protein Binding | Apoptosis - physiology | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Neoplasms - pathology | Proto-Oncogene Proteins c-mdm2 - metabolism | Tumor proteins | Tumors | Apoptosis | Index Medicus | Original
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15. Full Text Renoprotective effects of topiroxostat for Hyperuricaemic patients with overt diabetic nephropathy study (ETUDE study): A prospective, randomized, multicentre clinical trial
by Mizukoshi, Toshihiro and Kato, Sawako and Ando, Masahiko and Sobajima, Hiroshi and Ohashi, Norimi and Naruse, Tomohiko and Saka, Yosuke and Shimizu, Hideaki and Nagata, Takanobu and Maruyama, Shoichi
Nephrology (Carlton, Vic.), ISSN 1320-5358, 11/2018, Volume 23, Issue 11, pp. 1023 - 1030
topiroxostat | albuminuria | diabetic nephropathy | randomized study | xanthine oxidoreductase inhibitor | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Blood Pressure | Glycated Hemoglobin A - analysis | Glomerular Filtration Rate | Kidney - drug effects | Prospective Studies | Nitriles - pharmacology | Humans | Middle Aged | Diabetic Nephropathies - drug therapy | Hyperuricemia - physiopathology | Male | Fatty Acid-Binding Proteins - urine | Creatinine - urine | Hyperuricemia - drug therapy | Diabetic Nephropathies - physiopathology | Albuminuria - drug therapy | Aged, 80 and over | Female | Aged | Pyridines - pharmacology | Nitriles - therapeutic use | Pyridines - therapeutic use | Clinical trials | Medicine, Experimental | Medical research | Diabetic nephropathies | Urine | Creatinine | Nephropathy | Epidermal growth factor receptors | Diabetes mellitus | Glucose | Diabetes | Patients | Glomerular filtration rate | Proteinuria | Index Medicus
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