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Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 10/2003, Volume 93, Issue 8, pp. 767 - 775
ABSTRACT—Intracellular signaling pathway mediated by small GTPase Rho and its effector Rho-kinase plays an important role in regulation of vascular smooth... 
Rho-kinase | Superoxide anion | Angiotensin II | Cardiovascular hypertrophy | Arteriosclerosis | NADPH OXIDASE | CARDIAC & CARDIOVASCULAR SYSTEMS | MESSENGER-RNA EXPRESSION | TYROSINE KINASES | arteriosclerosis | CHEMOATTRACTANT PROTEIN-1 EXPRESSION | angiotensin II | cardiovascular hypertrophy | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | superoxide anion | CORONARY-ARTERY SPASM | HYPERTENSIVE-RATS | MYOSIN PHOSPHATASE | NEOINTIMAL FORMATION | NADPH Oxidases - metabolism | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Rats, Inbred WKY | Cardiomegaly - pathology | Endothelium, Vascular - drug effects | Male | Vasoconstrictor Agents - toxicity | Endothelium, Vascular - enzymology | Hypertension - chemically induced | rho-Associated Kinases | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Superoxides - metabolism | Angiotensin II - toxicity | Organ Culture Techniques | Macrophages - physiology | Coronary Vessels - pathology | Protein-Serine-Threonine Kinases - physiology | Endothelium, Vascular - physiopathology | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Rats | Cardiomegaly - enzymology | Aorta, Thoracic - cytology | Cell Movement - drug effects | Animals | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | Cardiomegaly - chemically induced | Macrophages - drug effects | Vasodilation - drug effects
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2017, Volume 377, Issue 12, pp. 1119 - 1131
Patients with myocardial infarction and a high-sensitivity CRP level of 2 mg or more per liter were assigned to one of three canakinumab doses or placebo. The... 
C-REACTIVE PROTEIN | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | MYOCARDIAL-INFARCTION | STATIN THERAPY | CLONAL HEMATOPOIESIS | INFLAMMATION | CARDIOVASCULAR-DISEASE | INTERLEUKIN-1-BETA INHIBITION | RISK | CORONARY-ARTERY-DISEASE | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Secondary Prevention | Infection - etiology | Incidence | Dose-Response Relationship, Drug | Anti-Inflammatory Agents - adverse effects | C-Reactive Protein - metabolism | Lipids - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Anti-Inflammatory Agents - administration & dosage | Female | Neutropenia - chemically induced | Interleukin-1beta - antagonists & inhibitors | Stroke - prevention & control | Atherosclerosis - drug therapy | Double-Blind Method | Interleukin-1beta - immunology | Atherosclerosis - blood | Myocardial Infarction - drug therapy | Antibodies, Monoclonal - administration & dosage | Aged | Myocardial Infarction - prevention & control | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | C-reactive protein | Cytokines | Clinical trials | Cardiovascular disease | Innate immunity | Inflammation | Angina | Angina pectoris | Thrombosis | Cholesterol | Disease prevention | Proteins | Arteriosclerosis | Atherosclerosis | Cardiovascular diseases | Health risk assessment | Drug therapy | Drug dosages | Klinisk medicin | Clinical Medicine
Journal Article
In Vitro Cellular & Developmental Biology - Animal, ISSN 1071-2690, 2008, Volume 44, Issue 1/2, pp. 26 - 30
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 12/2008, Volume 122, Issue 6, pp. 1208 - 1214
Journal Article
by Kato, Norihiro and Loh, Marie and Takeuchi, Fumihiko and Verweij, Niek and Wang, Xu and Zhang, Weihua and NKelly, Tanika and Saleheen, D and Lehne, Benjamin and Leach, Irene Mateo and ng, Alexander and Abbott, James and Wahl, Simone and Tan, Sian-Tsung and Scott, William R and Campanella, Gianluca and Chadeau-Hyam, Marc and Afzal, Uzma and Ahluwalia, Tarunveer Singh and Bonder, Marc and Chen, Ping and Dehghan, Abbas and Edwards, Todd L and Esko, Tõnu and Go, Min Jin and Harris, Sarah and Hartiala, Jaana and Kasela, Silva and Kasturiratne, Anuradhani and Khor, C.C and Kleber, Marcus and Li, Huaixing and Mok, Zuan Yu and Nakatochi, Masahiro and Sapari, Nur Sabrina and Saxena, Richa and Stewart, Alexane F and Stolk, Lisette and Tabara, Yasuharu and Teh, Ai Ling and Wu, Ying and Wu, Jer-Yuarn and Zhang, Yi and Aits, Imke and Da Silva Couto Alves, Alexessander and Das, Shikta and Dorajoo, Rajkumar and CHopewell, Jemma and Kim, Yun Kyoung and WKoivula, Robert and Luan, Jian'An and Lyytikäinen, Leo-Pekka and NNguyen, Quang and Pereira, Mark A and Postmus, Douwe and TRaitakari, Olli and Scannell Bryan, Molly and Scott, Robert and Sorice, R and Tragante, Vinicius and Traglia, Michela and White, Jon and Yamamoto, Ken and Zhang, Yonghong and Adair, Linda and Ahmed, Alauddin and Akiyama, Koichi and Asif, Rasheed and Aung, Tin and Barroso, Inês and Bjonnes, Anew and Braun, Timothy R and Cai, Hui and Chang, Li-Ching and Chen, C.-H and Cheng, Ching-Yu and Chong, Yap-Seng and Collins, Francis and Courtney, Regina and Davies, Gail and Delgado, G and Do, Loi D and Doevendans, Pieter and Gansevoort, Ron and Gao, Ying and Grammer, Tanja B and Grarup, Niels and Grewal, Jagvir and Gu, D and SWander, Gurpreet and Hartikainen, A.L and Hazen, Stanley and He, Jing and Heng, Chew-Kiat and Hixso, E. James Ames and Hofman, Albert and Hsu, Chris and Huang, Wei and Husemoen, Lise Lotte and Hwang, Joo-Yeon and ... and InterAct Consortium and BIOS-consortium and LifeLines Cohort Study and CARDIo GRAMplusCD and The InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet
Nature Genetics, ISSN 1061-4036, 11/2015, Volume 47, Issue 11, pp. 1282 - 1293