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Journal Article
Nature, ISSN 0028-0836, 2013, Volume 503, Issue 7477, pp. 493 - 499
Adiponectin secreted from adipocytes binds to adiponectin receptors AdipoR1 and AdipoR2, and exerts antidiabetic effects via activation of AMPK and PPAR-alpha... 
CRUCIAL ROLE | SKELETAL-MUSCLE | ACTIVATED PROTEIN-KINASE | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | MECHANISMS | ADIPONECTIN LEVELS | EXPRESSION | Liver - pathology | Obesity - drug therapy | Longevity - drug effects | Adipose Tissue, White - metabolism | Receptors, Adiponectin - metabolism | Diabetes Mellitus, Type 2 - metabolism | Muscle Fibers, Skeletal - drug effects | Obesity - genetics | Glucose Intolerance - drug therapy | Liver - drug effects | Piperidines - pharmacology | Inflammation - drug therapy | Adenylate Kinase - metabolism | Diet, High-Fat | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Receptors, Adiponectin - agonists | Adiponectin - metabolism | Drug Evaluation, Preclinical | Diabetes Mellitus, Type 2 - complications | Adipose Tissue, White - pathology | Adiponectin - pharmacology | Dyslipidemias - drug therapy | Piperidines - administration & dosage | Administration, Oral | Obesity - complications | Piperidines - metabolism | Liver - metabolism | Diabetes Mellitus, Type 2 - prevention & control | Insulin Resistance | Obesity - physiopathology | Transcription Factors - biosynthesis | Mitochondria - metabolism | Mitochondria - drug effects | Enzyme Activation - drug effects | Triglycerides - metabolism | Small Molecule Libraries - chemistry | Receptors, Adiponectin - deficiency | Animals | Signal Transduction - drug effects | Piperidines - therapeutic use | Muscle Fibers, Skeletal - cytology | Mice | Oxidative Stress - drug effects | PPAR alpha - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Adipose Tissue, White - drug effects | Receptors, Adiponectin - genetics | Muscles - cytology | Obesity | Insulin resistance | Muscular system | Kinases | Rodents
Journal Article
Journal Article
The Journal of Biochemistry, ISSN 0021-924X, 09/2018, Volume 164, Issue 3, pp. 247 - 255
Abstract cf3-Aequorin is one of the semi-synthetic aequorins that was produced by replacing 2-peroxycoelenterazine (CTZ-OOH) in native aequorin with a... 
COELENTERAZINE | OXIDATION | van der Waals interaction | calcium-binding protein | photoprotein | REGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | water molecules | CA2+-REGULATED PHOTOPROTEIN OBELIN | RECOMBINANT AEQUORIN | EF-hand motif | BLUE FLUORESCENT PROTEIN | EXTRACTION | SEQUENCE | BIOLUMINESCENCE
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 12/2018, Volume 217, Issue 12, pp. 4155 - 4163
The Tau family microtubule-associated proteins (MAPs) promote microtubule stabilization and regulate microtubule-based motility. They share the C-terminal... 
VISUALIZATION | CONFORMATIONAL-CHANGES | PROTEIN | FILAMENTS | CRYO-EM STRUCTURES | DECORATION | TRAFFICKING | IMPLEMENTATION | DIFFERENTIAL REGULATION | BINDING | CELL BIOLOGY | Binding | Alternative splicing | Motility | Splicing | Stabilization | Molecular motors | Proteins | Domains | Tubulin | Microtubule-associated proteins | Dimers | Inhibition | Bonding | Kinesin
Journal Article
Nature Communications, ISSN 2041-1723, 08/2016, Volume 7, Issue 1, pp. 12586 - 12586
Canonical Wnt/beta-catenin signalling is essential for maintaining intestinal stem cells, and its constitutive activation has been implicated in colorectal... 
COLON-CANCER | CARCINOMA CELLS | APC | PATHWAY | MULTIDISCIPLINARY SCIENCES | MICE | FACTOR-I | DIFFERENTIATION | NCK-INTERACTING KINASE | BETA-CATENIN | WNT | Index Medicus
Journal Article