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Experimental Hematology, ISSN 0301-472X, 08/2019, Volume 76, pp. S30 - S30
Journal Article
Blood, ISSN 0006-4971, 02/2018, Volume 131, Issue 5, pp. 496 - 504
Age-related alterations in the human blood system occur in B cells, T cells, cells of the innate system, as well as hematopoietic stem and progenitor cells... 
STEM-CELLS | EVOLUTION | TET2 MUTATIONS | DNMT3A | PATTERNS | X-CHROMOSOME INACTIVATION | LEUKEMIA | HEMATOLOGY | SOMATIC MUTATIONS | BLOOD | MOSAICISM
Journal Article
Haematologica, ISSN 0390-6078, 04/2019, Volume 104, Issue 5, pp. 872 - 880
The ontogeny of acute myeloid leukemia is a multistep process. It is driven both by features of the malignant clone itself as well as by environmental... 
RELAPSE | THERAPY | ACUTE MYELOGENOUS LEUKEMIA | HEMATOPOIETIC STEM-CELLS | DNMT3A | ACUTE MYELOID-LEUKEMIA | TP53 MUTATIONS | HEMATOLOGY | MINIMAL RESIDUAL DISEASE | SOMATIC MUTATIONS | ACUTE PROMYELOCYTIC LEUKEMIA | Review
Journal Article
Blood, ISSN 0006-4971, 09/2016, Volume 128, Issue 9, pp. 1162 - 1163
In this issue of Blood, Mossner et al took an important step in delineating the evolution of myelodysplastic syndrome (MDS). They were able to estimate... 
ACUTE-LEUKEMIA | RELAPSE | MUTATIONS | HEMATOLOGY | CANCER | CLONAL HEMATOPOIESIS | Myelodysplastic Syndromes | Wind | Humans
Journal Article
Cell, ISSN 0092-8674, 09/2018, Volume 175, Issue 1, p. 171
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.cell.2018.07.045... 
Medical research | Analysis | Leukemia | Medicine, Experimental | Jewish schools | Models | Genetic aspects | Genetic transcription | Tumor proteins
Journal Article
Experimental Hematology, ISSN 0301-472X, 09/2017, Volume 53, p. S77
Journal Article
Experimental Hematology, ISSN 0301-472X, 09/2017, Volume 53, pp. S77 - S77
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2013, Volume 1048, pp. 11 - 18
Cellular senescence plays important roles in the aging process of complex organisms, in response to stress and in tumor suppression. Several markers can be... 
Biomarkers - metabolism | Cell Line | Humans | Staining and Labeling | Cellular Senescence - physiology | Cytoplasm - metabolism | beta-Galactosidase - chemistry | Image Processing, Computer-Assisted - methods
Journal Article
European Journal of Medical Genetics, ISSN 1769-7212, 2019, p. 103643
Majewski Osteodysplastic Primordial Dwarfism type II (MOPDII) is a form of dwarfism associated with severe microcephaly, characteristic skeletal findings,... 
Microcephalic primordial dwarfism | Druze | PCNT | Founder
Journal Article
American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting, 2015, pp. e662 - e665
Somatic/clonal evolution is the process of sequential acquisition of vertically transmittable genetic/epigenetic elements in multicellular organisms. Cancer is... 
Precancerous Conditions - diagnosis | Neoplasms - genetics | Humans | Neoplastic Stem Cells - pathology | Precancerous Conditions - pathology | Neoplasms - diagnosis | Neoplasms - pathology | Precancerous Conditions - genetics | Genetic Heterogeneity | Clonal Evolution
Journal Article
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7639, p. 124
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 16 - 16
Abstract The NOD.SCID xenotransplantation assay is a key model system for interrogating the biology of leukemic stem cells (LSCs) in human acute myeloid... 
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 538, Issue 7625, pp. 378 - 382
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 328 - 333
In acute myeloid leukaemia (AML), the cell of origin, nature and biological consequences of initiating lesions, and order of subsequent mutations remain poorly... 
HETEROGENEITY | PATHOGENESIS | ORIGIN | METASTASIS | MULTIDISCIPLINARY SCIENCES | ARCHITECTURE | DNA METHYLTRANSFERASE | CLONAL EVOLUTION | ACUTE MYELOID-LEUKEMIA | DNMT3A MUTATIONS | DIFFERENTIATION | Clone Cells - cytology | Neoplasm Transplantation | Neoplastic Stem Cells - cytology | Neoplastic Stem Cells - drug effects | Humans | Hematopoietic Stem Cells - pathology | DNA (Cytosine-5-)-Methyltransferases - metabolism | Heterografts | Neoplastic Stem Cells - metabolism | T-Lymphocytes - metabolism | Hematopoiesis | Cell Division | Leukemia, Myeloid, Acute - drug therapy | Neoplastic Stem Cells - pathology | Female | Cell Differentiation | T-Lymphocytes - pathology | Nuclear Proteins - genetics | Hematopoietic Stem Cells - drug effects | Leukemia, Myeloid, Acute - pathology | Isocitrate Dehydrogenase - genetics | Hematopoietic Stem Cells - metabolism | Mice, SCID | Mutation - genetics | Clone Cells - metabolism | Remission Induction | Cell Lineage | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Clone Cells - pathology | Leukemia, Myeloid, Acute - diagnosis | Hematopoietic Stem Cells - cytology | Mice, Inbred NOD | Mice | Drug Resistance, Neoplasm - drug effects | Leukemia, Myeloid, Acute - genetics | Acute leukemia | Genetic aspects | Diagnosis | Identification and classification | Hematopoietic stem cells
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2530 - 2530
Patients with relapsed AML (Acute Myeloid Leukemia) have a poor prognosis and few therapeutic options. Therefore, it remains critical to identify biological... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 1451 - 1451
Background: Recent advances in acute myeloid leukemia(AML) targeted therapy improve overall survival. While these targeted therapies can achieve prolonged... 
Journal Article
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