X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (16) 16
index medicus (16) 16
article (9) 9
animals (8) 8
female (8) 8
mice (8) 8
gene (7) 7
hemic and lymphatic diseases (7) 7
male (6) 6
adult (5) 5
expression (5) 5
leukemia (5) 5
oncology (5) 5
adolescent (4) 4
child (4) 4
dna-binding proteins - genetics (4) 4
iran (4) 4
middle aged (4) 4
molecular sequence data (4) 4
parkinson disease - genetics (4) 4
precursor cell lymphoblastic leukemia-lymphoma - genetics (4) 4
precursor cell lymphoblastic leukemia-lymphoma - metabolism (4) 4
precursor cell lymphoblastic leukemia-lymphoma - pathology (4) 4
proto-oncogene proteins c-bcl-6 (4) 4
signal transduction (4) 4
young adult (4) 4
acute lymphocytic leukemia (3) 3
age of onset (3) 3
aged (3) 3
b cells (3) 3
b-lymphocytes - metabolism (3) 3
cell biology (3) 3
cell line, tumor (3) 3
dna-binding proteins - metabolism (3) 3
drug resistance (3) 3
gene expression regulation, neoplastic (3) 3
genetic aspects (3) 3
intracellular signaling peptides and proteins - metabolism (3) 3
kinases (3) 3
medicine, research & experimental (3) 3
mice, inbred nod (3) 3
mice, scid (3) 3
mice, transgenic (3) 3
multidisciplinary sciences (3) 3
mutation (3) 3
mutations (3) 3
parkinson's disease (3) 3
precursor b-cell lymphoblastic leukemia-lymphoma - genetics (3) 3
precursor b-cell lymphoblastic leukemia-lymphoma - metabolism (3) 3
precursor b-cell lymphoblastic leukemia-lymphoma - pathology (3) 3
precursor cells, b-lymphoid - metabolism (3) 3
proteins (3) 3
receptor (3) 3
survival (3) 3
transcription, genetic (3) 3
activation (2) 2
acute lymphoblastic-leukemia (2) 2
aged, 80 and over (2) 2
analysis (2) 2
apoptosis (2) 2
association (2) 2
b-lymphocytes - drug effects (2) 2
b-lymphocytes - pathology (2) 2
base sequence (2) 2
biochemistry & molecular biology (2) 2
biomarkers, tumor - genetics (2) 2
biomarkers, tumor - metabolism (2) 2
cancer research (2) 2
cell death (2) 2
cell proliferation (2) 2
cells (2) 2
clinical neurology (2) 2
disease models, animal (2) 2
drug resistance, neoplasm (2) 2
drug resistance, neoplasm - genetics (2) 2
fusion proteins, bcr-abl - genetics (2) 2
gene expression (2) 2
genetic linkage (2) 2
genetic predisposition to disease (2) 2
genetics (2) 2
germinal-center formation (2) 2
haplotype reconstruction (2) 2
health aspects (2) 2
hunger (2) 2
in-vitro (2) 2
inhibitor (2) 2
intracellular signaling peptides and proteins - genetics (2) 2
leucine-rich repeat serine-threonine protein kinase-2 (2) 2
lrrk2 (2) 2
minimal residual disease (2) 2
pedigree (2) 2
philadelphia-chromosome (2) 2
physiological aspects (2) 2
population (2) 2
precursor b-cell lymphoblastic leukemia-lymphoma - drug therapy (2) 2
precursor cell lymphoblastic leukemia-lymphoma - drug therapy (2) 2
proliferation (2) 2
properties (2) 2
protein-serine-threonine kinases - genetics (2) 2
protein-tyrosine kinases - metabolism (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 479 - 483
B-lymphoid transcription factors, such as PAX5 and IKZF1, are critical for early B-cell development(1,2), yet lesions of the genes encoding these transcription... 
ENERGY STRESS | ACTIVATION | GENE | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOPOIETIC STEM-CELLS | REGULATORY NETWORK | DIFFERENTIATION | MINIMAL RESIDUAL DISEASE | EXPRESSION | Glucocorticoids - therapeutic use | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Receptor, Cannabinoid, CB2 - agonists | Humans | Gene Expression Regulation, Neoplastic | Receptors, Glucocorticoid - metabolism | PAX5 Transcription Factor - deficiency | Carrier Proteins - agonists | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Chromatin Immunoprecipitation | Adenosine Triphosphate - metabolism | Cell Death | Pyruvic Acid - metabolism | Female | Ikaros Transcription Factor - metabolism | Energy Metabolism - genetics | B-Lymphocytes - metabolism | PAX5 Transcription Factor - metabolism | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | AMP-Activated Protein Kinases - antagonists & inhibitors | Carcinogenesis - genetics | PAX5 Transcription Factor - genetics | Mice, Transgenic | Citric Acid Cycle | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Transcription Factors - metabolism | B-Lymphocytes - drug effects | Receptor, Cannabinoid, CB2 - metabolism | Animals | Carrier Proteins - metabolism | Sequence Analysis, RNA | Glucocorticoids - pharmacology | Glucose - metabolism | Mice | Physiological aspects | Transcription factors | B cells | Proteins | Metabolites | Rodents | Cloning | Leukemia | Glucose | Kinases | Metabolism | Gene expression | Apoptosis
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2016, Volume 22, Issue 4, pp. 379 - 387
Journal Article
Nature, ISSN 0028-0836, 05/2015, Volume 521, Issue 7552, pp. 357 - 361
B cells are selected for an intermediate level of B-cell antigen receptor (BCR) signalling strength: attenuation below minimum(for example, non-functional... 
MOTIFS | RECEPTOR | ACTIVATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DELETION | Protein-Tyrosine Kinases - metabolism | Receptors, Antigen, B-Cell - deficiency | Humans | Precursor Cells, B-Lymphoid - metabolism | Inositol Polyphosphate 5-Phosphatases | Intracellular Signaling Peptides and Proteins - metabolism | Precursor Cells, B-Lymphoid - drug effects | Receptors, Antigen, B-Cell - metabolism | Antigens, CD - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Precursor Cells, B-Lymphoid - pathology | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Gene Deletion | Female | B-Lymphocytes - pathology | Cell Death - drug effects | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Syk Kinase | B-Lymphocytes - metabolism | Disease Models, Animal | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Enzyme Activation - drug effects | Mice, SCID | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | B-Lymphocytes - drug effects | Fusion Proteins, bcr-abl - genetics | Tyrosine - metabolism | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Signal Transduction - drug effects | Cell Transformation, Neoplastic | Intracellular Signaling Peptides and Proteins - agonists | Cell Line, Tumor | Mice, Inbred NOD | Receptors, Antigen, B-Cell - genetics | Mice | Amino Acid Motifs - genetics | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases | Phosphoric Monoester Hydrolases - metabolism | Receptors, Immunologic - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - deficiency | Receptors, Immunologic - metabolism | Drug Resistance, Neoplasm - drug effects | Physiological aspects | Acute lymphocytic leukemia | B cells | Signal transduction | Rodents | Leukemia | Mutation | Drug resistance | Kinases | Cells
Journal Article
Cancer Research, ISSN 0008-5472, 10/2013, Volume 73, Issue 19 Supplement, pp. A55 - A55
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 5469 - 5469
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 568 - 568
Abstract Background and significance: Activation of STAT5- and ERK-signaling are segregated to early and later stages of normal B cell development,... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 438 - 438
Abstract Background and Hypothesis: The transcriptional repressor and proto-oncogene BCL6 is a therapeutic target in subtypes of diffuse large B cell lymphoma... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 3944 - 3944
Background and significance: Normal B-cells constantly exchange information with their environment and depend on external cues for proliferation and survival... 
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 1301 - 1301
Abstract Abstract 1301 Background: BCL6-interacting corepressor (BCOR) has been first characterized as a BCL6-binding protein and co-repressor of BCL6 along... 
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 2447 - 2447
Journal Article
Nature, ISSN 0028-0836, 05/2011, Volume 473, Issue 7347, pp. 384 - 391
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2015, Volume 28, Issue 1, pp. 114 - 128
Studying mechanisms of malignant transformation of human pre-B cells, we found that acute activation of oncogenes induced immediate cell death in the vast... 
SPROUTY2 | INHIBITION | ONCOLOGY | PATHWAY | PHILADELPHIA-CHROMOSOME | KINASE | PROLIFERATION | SENESCENCE | MUTATIONS | TUMORIGENESIS | DUSP6 | CELL BIOLOGY | Small Molecule Libraries - pharmacology | Dual Specificity Phosphatase 6 - genetics | Prognosis | Humans | Molecular Sequence Data | Intracellular Signaling Peptides and Proteins - metabolism | DNA-Binding Proteins - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Cell Transformation, Neoplastic - genetics | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Intracellular Signaling Peptides and Proteins - genetics | Membrane Proteins - genetics | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Mice, Transgenic | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Cell Transformation, Neoplastic - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Transcription Factors - metabolism | Dual Specificity Phosphatase 6 - metabolism | Animals | MAP Kinase Signaling System - drug effects | Host Cell Factor C1 | Membrane Proteins - antagonists & inhibitors | Mice | Cell Transformation, Neoplastic - pathology | Hunger | B cells | Acute lymphocytic leukemia | Health aspects | Analysis | Medical research | Phosphatases | Cell death | Medicine, Experimental | Drug resistance
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 556 - 556
Abstract Background & Hypothesis: In ~50% of cases of acute lymphoblastic leukemia, activating lesions in RAS pathway are found. These lesions are particularly... 
Journal Article
Blood, ISSN 0006-4971, 11/2010, Volume 116, Issue 21, pp. 513 - 513
Abstract Abstract 513 Background: The phosphatase and tensin homolog (PTEN) tumor suppressor is a negative regulator of PI3K/AKT signaling and frequently... 
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2015, Volume 27, Issue 3, pp. 409 - 425
Journal Article
Leukemia, ISSN 0887-6924, 05/2016, Volume 30, Issue 5, pp. 1155 - 1165
Journal Article