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Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 5674 - 5674
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 10/2017, Volume 118, Issue 10, pp. 3043 - 3048
Journal Article
Immunity, Inflammation and Disease, ISSN 2050-4527, 12/2016, Volume 4, Issue 4, pp. 427 - 440
In this study, we have used the NSG‐SCF/GM‐CSF/IL3 (NSG‐SGM3) strain of mice engrafted with human fetal thymus, liver, and HSC (BLT) to establish a novel... 
cytokine | B cells | hematopoietic stem cells | SCID | humanized mice | Humanized mice | Hematopoietic stem cells | Cytokine | Antigens | Immunoglobulins | Dendritic cells | Cytokines | Liver | Dengue fever | Infections | Vaccines | Experiments | Granulocytes | Lymphocytes | Stem cells | Bone marrow | Laboratory animals | Viral infections | Index Medicus
Journal Article
Frontiers in genetics, ISSN 1664-8021, 2018, Volume 9, p. 233
Tylosis with esophageal cancer syndrome (TOC) is a rare autosomal dominant proliferative skin disease caused by missense mutations in the rhomboid 5 homolog 2... 
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 06/2014, Volume 59, Issue 6, p. 1169
  Stromal cells and the extracellular environment are vital to human tumors, influencing growth and response to therapy. Human tumor cell lines lack stroma and... 
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 2014, Volume 59, Issue 6, pp. 1169 - 1179
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 4, pp. 364 - 370
The identification of activating NOTCH1 mutations in T cell acute lymphoblastic leukemia (T-ALL) led to clinical testing of g-secretase inhibitors (GSIs) that... 
NOTCH1 | INHIBITION | CHROMATIN | PATHWAY | GENES | GENETICS & HEREDITY | C-MYC | ACUTE MYELOID-LEUKEMIA | CANCER | LENTIVIRAL RNAI LIBRARY | GENOME | Chromatin - metabolism | Humans | Flow Cytometry | Chromatin Immunoprecipitation | Gene Expression Regulation, Neoplastic - drug effects | Indoles | Nuclear Proteins - genetics | Real-Time Polymerase Chain Reaction | Gene Expression Regulation, Neoplastic - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Enzyme-Linked Immunosorbent Assay | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Signal Transduction - genetics | Transcription Factors - genetics | Enzyme Inhibitors - therapeutic use | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Epigenesis, Genetic - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Histones - metabolism | Receptor, Notch1 - antagonists & inhibitors | Receptor, Notch1 - genetics | Chromatin - genetics | Care and treatment | Pharmacology, Experimental | Acute lymphocytic leukemia | Research | Drug resistance | Proteins | Genotype & phenotype | Leukemia | Epigenetics | Genomes | Kinases | Gene expression | Cancer therapies | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2015, Volume 27, Issue 4, pp. 516 - 532
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 07/2010, Volume 107, Issue 29, pp. 13022 - 13027
Whereas humanized mouse models have contributed significantly to human immunology research, human T cells developing in mouse thymic environment fail to... 
Human immunology | HLA restriction | Epstein-Barr virus | T-cell development | Biological Sciences | human immunology | Epstein–Barr virus
Journal Article
Blood, ISSN 0006-4971, 09/2005, Volume 106, Issue 5, pp. 1565 - 1573
Here we report that a new nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse line harboring a complete null mutation of the common cytokine... 
Hematopoiesis
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2005, Volume 175, Issue 9, pp. 5666 - 5674
Journal Article
Journal Article