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Journal of Biological Chemistry, ISSN 0021-9258, 06/2009, Volume 284, Issue 26, pp. 17365 - 17369
DNA ligases seal 5′-PO 4 and 3′-OH polynucleotide ends via three nucleotidyl transfer steps involving ligase-adenylate and DNA-adenylate intermediates. DNA... 
MYCOBACTERIUM-TUBERCULOSIS | REPAIR | ADENYLATE | RNA LIGASE-1 | MECHANISM | SPECIFICITY | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIGATION | NICKED DNA | IDENTIFICATION | DNA Ligases - genetics | Humans | DNA Ligases - chemistry | DNA Ligases - metabolism | Enzymes | polynucleotides | DNA | Substrate specificity | genomics | Nucleotides | Phylogeny | nucleic acids | Crystal structure | Minireview
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2019, Volume 73, Issue 6, pp. 1085 - 1086
Journal Article
RNA, ISSN 1355-8382, 04/2015, Volume 21, Issue 4, pp. 735 - 737
The 5' m super(7)GpppN cap, co-discovered by Shatkin, Furuichi, and Moss in 1975, is the signature feature of eukaryal cellular and viral messenger RNA that... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | RNA Caps | RNA, Messenger - genetics | Personal Reflections
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 02/2017, Volume 199, Issue 3, p. E00739
  5'- and 3'-end-healing reactions are key steps in nucleic acid break repair in which 5'-OH ends are phosphorylated by a polynucleotide kinase (Pnk) and... 
Enzymes | Phosphorylation | Polypeptides | RNA-protein interactions | Gram-negative bacteria | Kinases | Adenosine triphosphatase
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 03/2016, Volume 44, Issue 5, pp. 2298 - 2309
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 03/2016, Volume 44, Issue 5, pp. 2298 - 2309
Escherichia coli DNA ligase (EcoLigA) repairs 3'-OH/5'-PO sub(4) nicks in duplex DNA via reaction of LigA with NAD super(+) to form a covalent LigA-(lysyl-N... 
Journal Article
JOURNAL OF BACTERIOLOGY, ISSN 0021-9193, 08/2019, Volume 201, Issue 16
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 11/2007, Volume 5, Issue 11, pp. 852 - 861
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 08/2015, Volume 197, Issue 15, p. 2489
  Mycobacterium smegmatis encodes several DNA repair polymerases that are adept at incorporating ribonucleotides, which raises questions about how... 
Enzymes | Bacteria | Biochemistry | Ribonucleic acid--RNA | Deoxyribonucleic acid--DNA | Bacteriology
Journal Article
Journal of Genetic Counseling, ISSN 1059-7700, 10/2016, Volume 25, Issue 5, pp. 912 - 922
Obsessive-compulsive disorder (OCD) has primarily pediatric onset and well-documented unique impacts on family functioning. Limited research has assessed the... 
Human Genetics | Psychiatric genetic counseling | Ethics | Public Health | Biomedicine | Gynecology | Parents | Clinical Psychology | Obsessive-compulsive disorder | Qualitative | Pediatric | Adaptation | Obsessive‐compulsive disorder | RELATIVES | SCHIZOPHRENIA | BIPOLAR DISORDER | ATTITUDES | CHILDREN | ADOLESCENTS | GENETICS & HEREDITY | FAMILY ACCOMMODATION | QUALITY-OF-LIFE | MENTAL-ILLNESS | HEALTH | Obsessive-Compulsive Disorder - psychology | Family Relations | Parents - psychology | Humans | Middle Aged | Adult | Female | Male | British Columbia | Disease Management | Genetic Counseling | Parenting | Children's hospitals | Development and progression | Psychiatric services | Child psychopathology | Mentally ill | Domestic relations | Genetic counseling | Analysis | Medical genetics | Strategic planning (Business) | Genetic research | Family | Obsessive compulsive disorder | Mental disorders | Causal attributions | Population genetics | Aetiology | Genetic family histories | Parents & parenting | Grounded theory | Etiology | Counselling services | Blame | Obsessive-Compulsive neuroses | Children | Genetic counselling | Mental illness | Qualitative research | Family functioning | Management development programmes | Vignettes | Stigmatization | Counselling | Sick children | Guilt | Meaning | adaptation | qualitative | obsessive-compulsive disorder | psychiatric genetic counseling | pediatric | parents
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 45, p. E10652
The carboxy-terminal domain (CTD) code encrypted within the Y1S2P3T4S5P6S7 heptad repeats of RNA polymerase II (Pol2) is deeply rooted in eukaryal biology. Key... 
Phosphates | Yeast | Transcription | Homeostasis | RNA polymerase | Gene expression | Termination factors | DNA-directed RNA polymerase | Fission | PHO1 gene | Polymerase | Ribonucleic acids | Derepression | Polyadenylation | Mutation | Viability | RNA polymerase II
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 04/2016, Volume 198, Issue 8, p. 1294
  Escherichia coli RtcB is a founding member of a family of manganese-dependent RNA repair enzymes that join RNA 2',3'-cyclic phosphate (RNA>p) or RNA... 
Phosphates | Enzymes | E coli | Mutagenesis | Ribonucleic acid--RNA | Crystal structure
Journal Article
Virology, ISSN 0042-6822, 2012, Volume 427, Issue 2, pp. 144 - 150
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 11/2015, Volume 197, Issue 22, p. 3616
  Escherichia coli RtcB exemplifies a family of GTP-dependent RNA repair/splicing enzymes that join 3'-PO... ends to 5'-OH ends via stable... 
Phosphates | Enzymes | E coli | Gram-negative bacteria | Ribonucleic acid--RNA | Deoxyribonucleic acid--DNA
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2013, Volume 288, Issue 20, pp. 14125 - 14134
Journal Article
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