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diagnosis (2) 2
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eculizumab (2) 2
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quality of life research (2) 2
quantitative sensory testing (2) 2
quantitative sudomotor axon reflex test (2) 2
recovery of function (2) 2
refractory materials (2) 2
rituximab (2) 2
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1. Full Text Autonomic involvement in Guillain–Barré syndrome: an update
by Zaeem, Zoya and Siddiqi, Zaeem A and Zochodne, Douglas W
Clinical Autonomic Research, ISSN 0959-9851, 6/2019, Volume 29, Issue 3, pp. 289 - 299
Guillain–Barré syndrome (GBS), an inflammatory, usually demyelinating polyradiculopathy, is characterized by ascending symmetrical limb weakness, sensory... 
Neurology | Medicine & Public Health | Gastroenterology | GBS | Diabetes | Ophthalmology | Dysautonomia | Cardiology | Endocrinology | Autonomic testing | Autonomic failure | Guillain-Barre syndrome | Mortality | Inflammation | Neuropathy | Autonomic nervous system | Demyelination | Reflexes
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2. Full Text Rituximab in refractory myasthenia gravis: Extended prospective study results
: Rituximab in Refractory MG
by Beecher, Grayson and Anderson, Dustin and Siddiqi, Zaeem A
Muscle & Nerve, ISSN 0148-639X, 09/2018, Volume 58, Issue 3, pp. 452 - 455
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3. Full Text Therapies Directed Against B-Cells and Downstream Effectors in Generalized Autoimmune Myasthenia Gravis: Current Status
by Beecher, Grayson and Putko, Brendan Nicholas and Wagner, Amanda Nicole and Siddiqi, Zaeem Azfer
Drugs, ISSN 0012-6667, 3/2019, Volume 79, Issue 4, pp. 353 - 364
Myasthenia gravis is a rare, heterogeneous, classical autoimmune disease characterized by fatigable skeletal muscle weakness, which is directly mediated by... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | IMMUNE DYSREGULATION | ACETYLCHOLINE-RECEPTOR ANTIBODY | MUSK | PASSIVE TRANSFER | CLINICAL-TRIALS | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | MONOCLONAL-ANTIBODY | TOXICOLOGY | AUTOANTIBODY PRODUCTION | T-CELLS | END-PLATE | Complement inhibitors | Target recognition | Clinical trials | Antibodies | Lymphocytes T | Cell interactions | Kinases | Subgroups | Immunosuppressive agents | Regulatory approval | Thymus | Proteins | Signal transduction | Heterogeneity | Neurotoxicity | Myasthenia gravis | Lymphocytes | Immunotherapy | Safety | Protein-tyrosine kinase | Immune system | Tyrosine | Immunoglobulins | Bortezomib | Autoantibodies | Cytokines | Therapeutic applications | Muscles | Rituximab | Skeletal muscle | Musculoskeletal system | Refractory materials | Inhibitors | Lymphocytes B | Stem cells | Neuromuscular junctions | Myasthenia | Acetylcholine | Autoimmune diseases | Binding sites
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4. Full Text Diagnostic Criteria for Small Fiber Neuropathy
by Blackmore, Derrick and Siddiqi, Zaeem A
Journal of Clinical Neuromuscular Disease, ISSN 1522-0443, 03/2017, Volume 18, Issue 3, pp. 125 - 131
OBJECTIVES:Despite its relative common occurrence, definitive diagnosis of small fiber neuropathy (SFN) remains problematic. In practice, patients with pain,... 
neuropathy | pinprick | quantitative sudomotor axon reflex test | quantitative sensory testing | Reflex - physiology | Vibration | Humans | Middle Aged | Male | Neural Conduction - physiology | Axons - physiology | Small Fiber Neuropathy - diagnosis | Electrodiagnosis - methods | Neurologic Examination | Sensitivity and Specificity | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Small Fiber Neuropathy - physiopathology
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5. Full Text Comparison of Usefulness of Cardiac Resynchronization Therapy in Patients with Type 1 Myotonic Dystrophy with –vs- without Left Bundle Branch Block
by Nikhanj, Anish and Sivakumaran, Soori and Yogasundaram, Haran and Becher, Harald and Kimber, Shane and Siddiqi, Zaeem A and Oudit, Gavin Y
The American Journal of Cardiology, ISSN 0002-9149, 09/2019
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6. Full Text Pinprick Testing in Small Fiber Neuropathy: Accuracy and Pitfalls
by Blackmore, Derrick and Siddiqi, Zaeem A
Journal of Clinical Neuromuscular Disease, ISSN 1522-0443, 06/2016, Volume 17, Issue 4, pp. 181 - 186
OBJECTIVES:To assess the sensitivity, specificity, and predictive value of pinprick perception and its concordance with established laboratory measures in... 
neurological examination | specificity | neuropathy | sensitivity | pinprick testing | quantitative sudomotor axon reflex test | diabetes | quantitative sensory testing | Physical Stimulation | Humans | Middle Aged | Male | Neural Conduction - physiology | Small Fiber Neuropathy - diagnosis | Touch Perception - physiology | Nerve Fibers - physiology | Neurologic Examination | Sensitivity and Specificity | Aged, 80 and over | Adult | Female | Aged | Skin | Small Fiber Neuropathy - physiopathology
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7. Full Text Rituximab in refractory myasthenia gravis: a prospective, open‐label study with long‐term follow‐up
by Anderson, Dustin and Phan, Cecile and Johnston, Wendy S and Siddiqi, Zaeem A
Annals of Clinical and Translational Neurology, ISSN 2328-9503, 07/2016, Volume 3, Issue 7, pp. 552 - 555
We examined the clinical effectiveness of rituximab in fourteen patients with refractory myasthenia gravis ( MG ). Manual muscle testing ( MMT ) score was... 
Immunoglobulins | Drug therapy | Health services | Patients | Drug dosages | Manuscripts
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8. Full Text Beyond the antibodies: serum metabolomic profiling of myasthenia gravis
by Blackmore, Derrick and Siddiqi, Zaeem and Li, Liang and Wang, Nan and Maksymowych, Walter
Metabolomics, ISSN 1573-3882, 8/2019, Volume 15, Issue 8, pp. 1 - 12
Myasthenia gravis (MG) is a chronic, potentially debilitating autoimmune disease characterized by weakness and rapid fatigue of the voluntary muscles that... 
Biochemistry, general | Biomedicine, general | Metabolomics | Neuromuscular disease | Cell Biology | Immunometabolomics | Life Sciences | Myasthenia gravis | Rheumatoid arthritis | Serum | Molecular Medicine | Autoimmune | Developmental Biology | OXIDATIVE STRESS | ACID | BIOMARKER | MUSCLE | IMMUNE | LC-MS | DISEASE | BIOLOGY | ENDOCRINOLOGY & METABOLISM | Rheumatoid factor | Medical research | Metabolites | Analysis | Medicine, Experimental | Fatigue | Arthritis | Discriminant analysis | Statistical analysis | Muscles | Multivariate analysis | Morbidity | Biomarkers | Neuromuscular junctions | Myasthenia | Autoimmune diseases
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9. Full Text Rituximab in refractory myasthenia gravis: Extended prospective study results
by Beecher, Grayson and Anderson, Dustin and Siddiqi, Zaeem A
Muscle & Nerve, ISSN 0148-639X, 09/2018, Volume 58, Issue 3, pp. 452 - 455
Introduction : Rituximab appears to be beneficial in treatment‐refractory myasthenia gravis (MG); however, prospective, long‐term durability data are lacking.... 
myasthenia gravis | refractory | seronegative | MuSK | rituximab | durability | MUSK MYASTHENIA | MULTICENTER | MANAGEMENT | B-CELL DEPLETION | NEUROSCIENCES | CLINICAL NEUROLOGY | Myasthenia gravis | Research
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10. Full Text Subcutaneous immunoglobulin in myasthenia gravis exacerbation A prospective, open-label trial
by Beecher, G and Anderson, D and Siddiqi, ZA
NEUROLOGY, ISSN 0028-3878, 09/2017, Volume 89, Issue 11, pp. 1135 - 1141
Objective: To investigate the efficacy, tolerability, and safety of subcutaneous immunoglobulin (SCIg) in patients with mild to moderate myasthenia gravis (MG)... 
PLASMA-EXCHANGE | INTRAVENOUS IMMUNOGLOBULIN | CLINICAL NEUROLOGY | Disability Evaluation | Severity of Illness Index | Myasthenia Gravis - blood | Humans | Middle Aged | Immunologic Factors - administration & dosage | Male | Immunoglobulins - administration & dosage | Subcutaneous Absorption | Young Adult | Pilot Projects | Self Administration | Immunoglobulins - blood | Aged, 80 and over | Immunoglobulins - adverse effects | Adult | Female | Aged | Immunologic Factors - adverse effects | Myasthenia Gravis - drug therapy
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11. Full Text Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
by Howard, James F and Utsugisawa, Kimiaki and Benatar, Michael and Murai, Hiroyuki and Barohn, Richard J and Illa, Isabel and Jacob, Saiju and Vissing, John and Burns, Ted M and Kissel, John T and Muppidi, Srikanth and Nowak, Richard J and O'Brien, Fanny and Wang, Jing-Jing and Mantegazza, Renato and Mazia, Claudio Gabriel and Wilken, Miguel and Ortea, Carolina and Saba, Juliet and Rugiero, Marcelo and Bettini, Mariela and Vidal, Gonzalo and Vidal, Nuria and Garcia, Rebekah and Garcia, Sonia and Garcia, Alejandra Dalila and Lamont, Phillipa and Leong, Wai-Kuen and Boterhoven, Heidi and Fyfe, Beverly and Roberts, Leslie and Jasinarachchi, Mahi and Willlems, Natasha and Wanschitz, Julia and Löscher, Wolfgang and De Bleecker, Jan and Van den Abeele, Guy and de Koning, Kathy and De Mey, Katrien and Mercelis, Rudy and Wagemaekers, Linda and Mahieu, Delphine and Van Damme, Philip and Smetcoren, Charlotte and Stevens, Olivier and Verjans, Sarah and D'Hondt, Ann and Tilkin, Petra and Alves de Siqueira Carvalho, Alzira and Hasan, Rosa and Dias Brockhausen, Igor and Feder, David and Ambrosio, Daniel and Melo, Ana Paula and Rocha, Rosana and Rosa, Bruno and Veiga, Thabata and Augusto da Silva, Luiz and Gonçalves Geraldo, Jordana and da Penha Morita Ananias, Maria and Nogueira Coelho, Erica and Paiva, Gabriel and Pozo, Marina and Prando, Natalia and Dada Martineli Torres, Debora and Fernanda Butinhao, Cristiani and Coelho, Erica and Renata Cubas Volpe, Luciana and Duran, Gustavo and Gomes da Silva, Tamires Cristina and Otavio Maia Gonçalves, Luiz and Pazetto, Lucas Eduardo and Souza Duca, Luciana and Suriane Fialho, Tomás Augusto and Gheller Friedrich, Maurício André and Guerreiro, Alexandre and Mohr, Henrique and Pereira Martins, Maurer and da Cruz Pacheco, Daiane and Macagnan, Ana Paula and de Cassia Santos, Aline and Bulle Oliveira, Acary Souza and Amaral de Andrade, Ana Carolina and Annes, Marcelo and Cavalcante Lino, Valeria and Pinto, Wladimir and Miranda, Carolina and Carrara, Fernanda and Souza, Iandra and Genge, Angela and Massie, Rami and Campbell, Natasha and Bril, Vera and Katzberg, Hans and Soltani, Mehran and Ng, Eduardo and Siddiqi, Zaeem and Phan, Celile and Blackmore, Derrick and Vohanka, Stanislav and ... and REGAIN Study Grp and REGAIN Study Group
The Lancet Neurology, ISSN 1474-4422, 12/2017, Volume 16, Issue 12, pp. 976 - 986
Complement is likely to have a role in refractory generalised myasthenia gravis, but no approved therapies specifically target this system. Results from a... 
TRIAL | ENDPLATE | LOCALIZATION | COMPLEMENT INHIBITOR ECULIZUMAB | DAILY LIVING PROFILE | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | ACETYLCHOLINE-RECEPTOR | END-PLATE | CLINICAL NEUROLOGY | Severity of Illness Index | Antibodies, Monoclonal, Humanized - adverse effects | Double-Blind Method | Myasthenia Gravis - blood | Outcome Assessment (Health Care) | Autoantibodies - blood | Humans | Middle Aged | Male | Antibodies, Monoclonal, Humanized - administration & dosage | Myasthenia Gravis - physiopathology | Antibodies, Monoclonal, Humanized - pharmacology | Adult | Female | Receptors, Cholinergic - immunology | Aged | Myasthenia Gravis - drug therapy | Drug Resistance | Studies | Neurology | Immunoglobulins | Activities of daily living | Myasthenia gravis | Transplants & implants | Neuromuscular junctions | Acetylcholine | Myasthenia | Patients
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12. Full Text Label Free Proteomic Analysis Reveals Large Dynamic Changes to the Cellular Proteome Upon Expression of the miRNA-23a-27a-24-2 MicroRNA Cluster
by Piragasam, Ramanaguru S and Hussain, S Faraz and Chaulk, Steven G and Siddiqi, Zaeem A and Fahlman, Richard P
Biochemistry and cell biology = Biochimie et biologie cellulaire, ISSN 0829-8211, 05/2019
In deciphering the regulatory networks of gene expression controlled by the small non-coding RNAs known as microRNAs (miRNAs), a major challenge has been with... 
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13. Full Text Beyond the antibodies: serum metabolomic profiling of myasthenia gravis
by Blackmore, Derrick and Siddiqi, Zaeem and Li, Liang and Wang, Nan and Maksymowych, Walter
Metabolomics : Official journal of the Metabolomic Society, 08/2019, Volume 15, Issue 8, p. 109
Myasthenia gravis (MG) is a chronic, potentially debilitating autoimmune disease characterized by weakness and rapid fatigue of the voluntary muscles that... 
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14. Full Text Severe asthma associated with myasthenia gravis/Un asthme sévère associé à une myasthénie grave
by Natasha Satkunam and Zaeem A Siddiqi and Dilini Vethanayagam
Canadian Respiratory Journal, ISSN 1198-2241, 01/2014, Volume 21, Issue 1, p. E1
  Severe asthma constitutes a subgroup of approximately 10% of all asthma cases. Approximately one-half of these individuals have a refractory form of the... 
Genotype & phenotype | Immunology | Medical diagnosis | Asthma
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15. Full Text AMPA-R Limbic Encephalitis associated with Systemic Lupus Erythematosus: a case report
by Zaeem, Z and Luk, C and Anderson, D and Blevins, G and Siddiqi, Z
NEUROLOGY, ISSN 0028-3878, 04/2018, Volume 90
CLINICAL NEUROLOGY
Conference Proceeding
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16. Full Text Eculizumab improves fatigue in refractory generalized myasthenia gravis
by Andersen, Henning and Mantegazza, Renato and Wang, Jing Jing and O’Brien, Fanny and Patra, Kaushik and Howard Jr, James F and REGAIN Study Group and REGAIN Study Grp and The REGAIN Study Group
Quality of Life Research, ISSN 0962-9343, 8/2019, Volume 28, Issue 8, pp. 2247 - 2254
To evaluate the effect of eculizumab on perceived fatigue in patients with anti-acetylcholine receptor antibody-positive, refractory, generalized myasthenia... 
Public Health | Terminal complement inhibition | Myasthenia gravis | Medicine & Public Health | Quality of Life Research | Eculizumab | Fatigue | Complement | Sociology, general | Neuro-QOL Fatigue | Quality of life | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | HEALTH CARE SCIENCES & SERVICES | HEALTH POLICY & SERVICES | QUALITY-OF-LIFE | Analysis | Activities of daily living | Brief Communication
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