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Diabetes, Obesity and Metabolism, ISSN 1462-8902, 02/2016, Volume 18, Issue 2, pp. 191 - 195
Phase I studies have shown that AMG 151 activates glucokinase, a key enzyme in glucose homeostasis. The present randomized, placebo‐controlled phase IIa study... 
clinical trial | antidiabetic drug | glucokinase activator | type 2 diabetes | dose‐response relationship | Type 2 diabetes | Clinical trial | Antidiabetic drug | Glucokinase activator | Dose-response relationship | METFORMIN | THERAPY | ENDOCRINOLOGY & METABOLISM | dose-response relationship | Glycated Hemoglobin A - analysis | Hypoglycemia - epidemiology | Drugs, Investigational - adverse effects | Follow-Up Studies | Enzyme Activators - therapeutic use | Humans | Aminopyridines - adverse effects | Drugs, Investigational - therapeutic use | Incidence | Dose-Response Relationship, Drug | Hypoglycemia - prevention & control | Thiadiazoles - adverse effects | Aminopyridines - therapeutic use | Hypoglycemic Agents - administration & dosage | Enzyme Activators - administration & dosage | Thiadiazoles - therapeutic use | Postprandial Period | Adult | Hypoglycemia - chemically induced | Headache - chemically induced | Glucokinase - chemistry | Hypoglycemic Agents - therapeutic use | Aminopyridines - administration & dosage | Hyperglycemia - prevention & control | Blood Glucose - analysis | Double-Blind Method | Drug Administration Schedule | Glucokinase - metabolism | Diabetes Mellitus, Type 2 - blood | Hypertriglyceridemia - chemically induced | Hypertriglyceridemia - epidemiology | Headache - epidemiology | Enzyme Activators - adverse effects | Triglycerides - blood | Drugs, Investigational - administration & dosage | Least-Squares Analysis | Hyperglycemia - epidemiology | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Thiadiazoles - administration & dosage | Care and treatment | Fasting | Isoenzymes | Hypoglycemic agents | Glucose | Dextrose | Insulin | Diabetes | Index Medicus
Journal Article
Chest, ISSN 0012-3692, 12/2007, Volume 132, Issue 6, pp. 1863 - 1870
Journal Article
EUROPEAN HEART JOURNAL, ISSN 0195-668X, 09/2007, Volume 28, Issue 17, pp. 2087 - 2093
Background Emerging evidence suggests that a mildly elevated body mass index (BMI), is related to improved survival and fewer cardiovascular events in patients... 
MORTALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | AIR-DISPLACEMENT PLETHYSMOGRAPHY | body mass index | VALIDATION | diagnostic performance | COMMITTEE | cardiovascular risk factor | PATHOPHYSIOLOGY | CARDIOVASCULAR-DISEASE | FAT | PHYSICAL-ACTIVITY | ASSOCIATION | obesity | body fat
Journal Article
Diabetologia, ISSN 0012-186X, 2/2008, Volume 51, Issue 2, pp. 328 - 335
Journal Article
Journal Article
Journal Article
European Journal of Cardiovascular Prevention and Rehabilitation, ISSN 1741-8267, 06/2008, Volume 15, Issue 3, pp. 336 - 340
Journal Article
Mayo Clinic Proceedings, ISSN 0025-6196, 2009, Volume 84, Issue 10, pp. 941 - 942
Journal Article
EUROPEAN HEART JOURNAL, ISSN 0195-668X, 11/2007, Volume 28, Issue 21, pp. 2637 - 2643
Background Recently, the apoB/apoA1 ratio has been associated with the metabolic syndrome; however, is unclear if its association with insulin resistance is... 
apoB/apoA1 | risk factors | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | MYOCARDIAL-INFARCTION | CHOLESTEROL | Centres for disease control and prevention | HOMA2 | LIPID-LOWERING THERAPY | apoB | metabolic syndrome | HEART-DISEASE | MIDDLE-AGED MEN | CARDIOVASCULAR-DISEASE | NHANES | apoA1 | insulin resistance | CORONARY-ARTERY-DISEASE | APOLIPOPROTEIN-A-I
Journal Article
Value in Health, ISSN 1098-3015, 2011, Volume 14, Issue 7, pp. A332 - A332
Journal Article