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2008, Advances in experimental medicine and biology, ISBN 0387097880, Volume 640, xxvii, 357
This book shows how the structural similarity of MIRRs determines the general principles underlying MIRR-mediated transmembrane signaling mechanisms. In so... 
Killer cells | Cell receptors | Models, Immunological | Receptors | Signal Transduction | Immune recognition | Receptors, Immunologic | Cellular signal transduction | T cells | Oncology | Biomedicine general | Biomedicine
Book
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 2673 - 2673
Journal Article
International Immunopharmacology, ISSN 1567-5769, 07/2014, Volume 21, Issue 1, pp. 208 - 219
Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the inflammatory response and plays a role in cancer and sepsis. Inhibition of TREM-1 by... 
Sepsis | TREM-1 receptor | HDL nanoparticles | Targeted delivery | Therapeutic SCHOOL peptides | Non-small cell lung cancer | MACROPHAGES | IMMUNE DYSFUNCTION | RECEPTOR | NEUTROPHILS | IMMUNOLOGY | LIPOPROTEIN | INFLAMMATION | PATHWAY MODULATION | PHARMACOLOGY & PHARMACY | MYELOID CELLS-1 | APOLIPOPROTEIN-A-I | Lung Neoplasms - drug therapy | Nanoparticles - chemistry | Humans | Lipopolysaccharides - administration & dosage | Receptors, Immunologic - antagonists & inhibitors | Membrane Glycoproteins - antagonists & inhibitors | Shock, Septic - drug therapy | Lipoproteins, HDL - chemistry | Female | Macrophages, Peritoneal - drug effects | Lipoproteins, HDL - administration & dosage | Cytokines - metabolism | Shock, Septic - chemically induced | Cell Growth Processes - drug effects | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Macrophages, Peritoneal - immunology | Adenocarcinoma - drug therapy | Xenograft Model Antitumor Assays | Peptide Fragments - chemistry | Animals | Triggering Receptor Expressed on Myeloid Cells-1 | Tumor Burden - drug effects | Mice, Nude | Cell Line, Tumor | Mice | Nanoparticles - administration & dosage | Prevention | Peptides | Growth | Analysis | Septic shock | Lung cancer, Non-small cell | Mitogens | Tumors | Cancer | Index Medicus | non-small cell lung cancer | nanoparticles | therapeutic peptides | SCHOOL model of cell signaling | targeted delivery | sepsis | Macrophage
Journal Article
Molecular Immunology, ISSN 0161-5890, 07/2012, Volume 51, Issue 3-4, pp. 356 - 362
► Multivalency of apparently monovalent lipid and protein ligands is proposed. ► The concept is illustrated for toll-like receptor 4 and T cell receptor. ►... 
Ligand valency | Immune signaling | TLR-4 | T cell receptor | Micelles | MHC | Receptor clustering | LPSL | Lipid A | Toll-like receptor | Surface-bound
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 12/2008, Volume 47, Issue 49, pp. 12942 - 12944
Intrinsically disordered proteins are thought to undergo coupled binding and folding upon interaction with their folded partners. In this study, we investigate... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | MODULATION | ZETA-CHAIN | Biochemistry and Molecular Biology | modulation | Biokemi och molekylärbiologi | zeta-chain
Journal Article
Molecular BioSystems, ISSN 1742-206X, 2010, Volume 6, Issue 3, pp. 451 - 461
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2009, Volume 5, Issue 7
  [...]two unrelated viruses, HIV and human CMV, use a similar mode of action to modulate the host immune response mediated by two functionally different... 
Proteins | Signal transduction | Cytomegalovirus | Pathogenesis | Lymphocytes | Viruses | Ligands | T cell receptors | Viral infections | Immune system
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 10/2017, Volume 21, Issue 10, pp. 2524 - 2534
Triggering receptor expressed on myeloid cells 1 (TREM‐1) is critically involved in the pathogenesis of rheumatoid arthritis (RA). In contrast to cytokine... 
macrophages | inflammation | therapeutic peptides | targeted delivery | triggering receptor expressed on myeloid cells 1 | collagen‐induced arthritis | signalling chain homo‐oligomerization model of cell signalling | collagen-induced arthritis | signalling chain homo-oligomerization model of cell signalling | RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | PRO-INFLAMMATORY CYTOKINES | ACTIVATION | COLONY-STIMULATING FACTORS | ANTI-TNF THERAPY | LIPOPROTEIN PARTICLES | CELL BIOLOGY | TUMOR-NECROSIS-FACTOR | IN-VIVO | SERIOUS INFECTIONS | Amino Acid Sequence | Arthritis, Experimental - blood | Cell Line | Triggering Receptor Expressed on Myeloid Cells-1 - antagonists & inhibitors | Triggering Receptor Expressed on Myeloid Cells-1 - metabolism | Lipoproteins, HDL - metabolism | Male | Arthritis, Experimental - metabolism | Peptides - pharmacology | Macrophages - metabolism | Animals | Peptides - metabolism | Arthritis, Experimental - prevention & control | Drug Design | Protein Binding | Mice, Inbred DBA | Mice, Inbred BALB C | Microscopy, Fluorescence | Cytokines - blood | Oligomers | Arthritis | Peptides | Analysis | Collagen | Self assembly | Pathogenesis | Interleukin | Helices | Macrophages | Nanoparticles | Interleukin 6 | Cartilage | Apolipoprotein A | Microorganisms | Interleukin 1 | Colony-stimulating factor | Lipoproteins (high density) | Myeloid cells | Oligomerization | Cytokines | Macrophage colony-stimulating factor | Inflammation | Peptide inhibitors | Signaling | Lipoproteins | Self-assembly | Inhibitors | Tumor necrosis factor | Rheumatoid arthritis | Apolipoprotein A-I | Ligands | Plasma levels | Tumors | Original
Journal Article