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The New England Journal of Medicine, ISSN 0028-4793, 09/2017, Volume 377, Issue 12, pp. 1119 - 1131
Patients with myocardial infarction and a high-sensitivity CRP level of 2 mg or more per liter were assigned to one of three canakinumab doses or placebo. The... 
C-REACTIVE PROTEIN | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | MYOCARDIAL-INFARCTION | STATIN THERAPY | CLONAL HEMATOPOIESIS | INFLAMMATION | CARDIOVASCULAR-DISEASE | INTERLEUKIN-1-BETA INHIBITION | RISK | CORONARY-ARTERY-DISEASE | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Secondary Prevention | Infection - etiology | Incidence | Dose-Response Relationship, Drug | Anti-Inflammatory Agents - adverse effects | C-Reactive Protein - metabolism | Lipids - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Anti-Inflammatory Agents - administration & dosage | Female | Neutropenia - chemically induced | Interleukin-1beta - antagonists & inhibitors | Stroke - prevention & control | Atherosclerosis - drug therapy | Double-Blind Method | Interleukin-1beta - immunology | Atherosclerosis - blood | Myocardial Infarction - drug therapy | Antibodies, Monoclonal - administration & dosage | Aged | Myocardial Infarction - prevention & control | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | C-reactive protein | Cytokines | Clinical trials | Cardiovascular disease | Innate immunity | Inflammation | Angina | Angina pectoris | Thrombosis | Cholesterol | Disease prevention | Proteins | Arteriosclerosis | Atherosclerosis | Cardiovascular diseases | Health risk assessment | Drug therapy | Drug dosages | Index Medicus | Abridged Index Medicus | Klinisk medicin | Clinical Medicine
Journal Article
by Ripke, Stephan and Neale, Benjamin M and Corvin, Aiden and Walters, James T. R and Farh, Kai-How and Holmans, Peter A and Lee, Phil and Bulik-Sullivan, Brendan and Collier, David A and Huang, Hailiang and Pers, Tune H and Agartz, Ingrid and Agerbo, Esben and Albus, Margot and Alexander, Madeline and Amin, Farooq and Bacanu, Silviu A and Begemann, Martin and Belliveau, Richard A and Bene, Judit and Bergen, Sarah E and Bevilacqua, Elizabeth and Bigdeli, Tim B and Black, Donald W and Bruggeman, Richard and Buccola, Nancy G and Buckner, Randy L and Byerley, William and Cahn, Wiepke and Cai, Guiqing and Campion, Dominique and Cantor, Rita M and Carr, Vaughan J and Carrera, Noa and Catts, Stanley V and Chambert, Kimberly D and Chan, Raymond C. K and Chen, Ronald Y. L and Chen, Eric Y. H and Cheng, Wei and Cheung, Eric F. C and Chong, Siow Ann and Cloninger, C. Robert and Cohen, David and Cohen, Nadine and Cormican, Paul and Craddock, Nick and Crowley, James J and Curtis, David and Davidson, Michael and Davis, Kenneth L and Degenhardt, Franziska and del Favero, Jurgen and Demontis, Ditte and Dikeos, Dimitris and Dinan, Timothy and Djurovic, Srdjan and Donohoe, Gary and peau, Elodie and Duan, Jubao and Dudbridge, Frank and Durmishi, Naser and Eichhammer, Peter and Eriksson, Johan and Escott-Price, Valentina and Essioux, Laurent and Fanous, Ayman H and Farrell, Martilias S and Frank, Josef and Franke, Lude and Freedman, Robert and Freimer, Nelson B and Friedl, Marion and Friedman, Joseph I and Fromer, Menachem and Genovese, Giulio and Georgieva, Lyudmila and Giegling, Ina and Giusti-Roíguez, Paola and Godard, Stephanie and Goldstein, Jacqueline I and Golimbet, Vera and Gopal, Srihari and Gratten, Jacob and de Haan, Lieuwe and Hammer, Christian and Hamshere, Marian L and Hansen, Mark and Hansen, Thomas and Haroutunian, Vahram and Hartmann, Annette M and Henskens, Frans A and Herms, Stefan and Hirschhorn, Joel N and Hoffmann, Per and Hofman, Anea and Hollegaard, Mads V and Hougaard, David M and Ikeda, Masashi and Joa, Inge and ... and Psychiat Genomics Consortium and Wellcome Trust Case-Control Consor and Psychosis Endophenotypes Int Conso and Schizophrenia Working Group of the Psychiatric Genomics Consortium and Medicinska fakulteten and Institutionen för klinisk vetenskap and Psykiatri and Umeå universitet
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7510, pp. 421 - 427
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be... 
COMMON VARIANTS | MUTATIONS | MULTIDISCIPLINARY SCIENCES | CONFERRING RISK | GENOME-WIDE ASSOCIATION | Schizophrenia | Genetic research | Research | Health aspects | Analysis | Studies | Confidence intervals | Hypotheses | Genealogy | Sample size | Genomics | Genetics | Trends | Index Medicus | Clinical Medicine | Psykiatri | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Psychiatry
Journal Article
by Wray, Naomi R and Ripke, Stephan and Mattheisen, Manuel and Trzaskowski, MacIej and Byrne, Enda M and Abdellaoui, Abdel and Adams, Mark J and Agerbo, Esben and Air, Tracy M and Andlauer, Till M. F and Bacanu, Silviu-Alin and Bækvad-Hansen, Marie and Beekman, Aartjan F. T and Bigdeli, Tim B and Binder, Elisabeth B and Blackwood, Douglas R. H and Bryois, Julien and Buttenschøn, Henriette N and Bybjerg-Grauholm, Jonas and Cai, Na and Castelao, Enrique and Christensen, Jane Hvarregaard and Clarke, Toni-Kim and Coleman, Jonathan I. R and Colodro-Conde, Lucía and Couvy-Duchesne, Baptiste and Craddock, Nick and Crawford, Gregory E and Crowley, Cheynna A and Dashti, Hassan S and Davies, Gail and Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and DIrek, Nese and Dolan, Conor V and Dunn, Erin C and Eley, Thalia C and Eriksson, Nicholas and Escott-Price, Valentina and Kiadeh, Farnush Hassan Farhadi and Finucane, Hilary K and Forstner, Andreas J and Frank, Josef and Gaspar, Héléna A and Gill, Michael and Giusti-Rodríguez, Paola and Goes, Fernando S and Gordon, Scott D and Grove, Jakob and Hall, Lynsey S and Hannon, Eilis and Hansen, Christine Søholm and Hansen, Thomas F and Herms, Stefan and Hickie, Ian B and Hoffmann, Per and Homuth, Georg and Horn, Carsten and Hottenga, Jouke-Jan and Hougaard, David M and Hu, Ming and Hyde, Craig L and Ising, Marcus and Jansen, Rick and Jin, Fulai and Jorgenson, Eric and Knowles, James A and Kohane, Isaac S and Kraft, Julia and Kretzschmar, Warren W and Krogh, Jesper and Kutalik, Zoltán and Lane, Jacqueline M and Li, Yihan and Li, Yun and Lind, Penelope A and Liu, Xiaoxiao and Lu, Leina and MacIntyre, Donald J and MacKinnon, Dean F and Maier, Robert M and Maier, Wolfgang and Marchini, Jonathan and Mbarek, Hamdi and McGrath, Patrick and McGuffin, Peter and Medland, Sarah E and Mehta, DIvya and Middeldorp, Christel M and Mihailov, Evelin and Milaneschi, Yuri and Milani, Lili and Mill, Jonathan and Mondimore, Francis M and Montgomery, Grant W and Mostafavi, Sara and Mullins, Niamh and Nauck, Matthias and Ng, Bernard and ... and Major Depressive Disorder Working and EQTLGEN and eQTLGen and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and 23andMe and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Nature Genetics, ISSN 1061-4036, 05/2018, Volume 50, Issue 5, pp. 668 - 681
Journal Article