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2012, 2nd ed., Methods in molecular biology, ISBN 161779550X, Volume 849., xv, 548
Book
Progress in Molecular Biology and Translational Science, ISSN 1877-1173, 2019
Development of therapies for Alzheimer's disease has only resulted in a few approved drugs that provide some temporary symptomatic relief in certain patients.... 
Therapy | Neurotoxicity | Strains | Immunotherapy | Antibodies | Tau | Amyloid-β | Drug development | Drug screening | Alzheimer's disease | Seeding
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 06/2018, Volume 64, Issue s1, pp. S555 - S565
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 10/2018, Volume 66, Issue 2, pp. 855 - 856
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2013, Volume 288, Issue 49, pp. 35452 - 35465
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1779, p. V
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 2018, Volume 64, Issue 1, pp. S555 - S565
Journal Article
JOURNAL OF ALZHEIMERS DISEASE, ISSN 1387-2877, 2018, Volume 66, Issue 2, pp. 855 - 856
Journal Article
2012, 2nd ed., Methods in molecular biology, ISBN 161779550X, Volume 849
Web Resource
Journal of Alzheimer's Disease, ISSN 1387-2877, 01/2018, Volume 64, Issue s1, pp. S.555 - S565
Tau immunotherapies have now advanced from proof-of-concept studies to Phase II clinical trials. This review briefly outlines developments in the field and... 
Clinical trials | Medical research | Neurodegenerative diseases | Tau protein | Immunotherapy | immunotherapies | tauopathy | Alzheimer’s disease | tau | antibodies | clinical trials | mechanisms
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2014, Volume 10, Issue 4, pp. P123 - P123
Journal Article
mAbs, ISSN 1942-0862, 04/2019, Volume 11, Issue 3, pp. 477 - 488
Targeting tau with immunotherapies is currently the most common approach taken in clinical trials of patients with Alzheimer's disease. The most prominent... 
phospho-epitope | Monoclonal antibody | Alzheimer's disease | tau protein | antibody-antigen complex
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 09/2011, Volume 122, Issue 3, pp. 285 - 292
Journal Article
2005, Methods in molecular biology, ISBN 9781588293374, Volume 299
Web Resource
Journal of Neurochemistry, ISSN 0022-3042, 08/2011, Volume 118, Issue 4, pp. 658 - 667
Targeting hyperphosphorylated tau by immunotherapy is emerging as a promising approach to treat tauopathies such as Alzheimer's disease and frontotemporal... 
tau | tangles | behavior | mice | PHF1 | immunotherapy | NEUROFIBRILLARY TANGLES | A-BETA IMMUNIZATION | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | MEMORY LOSS | COGNITIVE DECLINE | PAIRED HELICAL FILAMENTS | A-BETA | AMYLOID-BETA IMMUNIZATION | TRANSGENIC MICE | Immunohistochemistry | Motor Activity - physiology | Phosphorylation | Neurodegenerative Diseases - psychology | Tauopathies - immunology | tau Proteins - immunology | Astrocytes - pathology | Brain Stem - metabolism | tau Proteins - metabolism | Antibodies, Monoclonal - therapeutic use | Neurodegenerative Diseases - immunology | Gliosis - pathology | Motor Cortex - metabolism | Brain Stem - pathology | Antibodies - analysis | Female | Brain Chemistry - immunology | Data Interpretation, Statistical | Dentate Gyrus - metabolism | Enzyme-Linked Immunosorbent Assay | Neurodegenerative Diseases - metabolism | Blotting, Western | Motor Cortex - pathology | Tauopathies - metabolism | Animals | Image Processing, Computer-Assisted | Antibodies, Blocking - therapeutic use | Brain - pathology | Immunization, Passive | Mice | Postural Balance - physiology | Dentate Gyrus - pathology | Brain | Neurosciences | Immunization | Alzheimer's disease | Analysis | Immunoglobulin G | Neurochemistry | Proteins | Brain research | Dementia | Index Medicus | Animal models | Neurodegenerative diseases | Brain stem | Cognitive ability | Antibodies | Western blotting | Dentate gyrus | Tau protein | Immunotherapy | Models | Plasma levels | Immunization (passive) | Immunoreactivity | Frontotemporal dementia | Age | Hippocampus
Journal Article
mAbs, ISSN 1942-0862, 04/2019, Volume 11, Issue 3, pp. 477 - 488
Targeting tau with immunotherapies is currently the most common approach taken in clinical trials of patients with Alzheimer's disease. The most prominent... 
phospho-epitope | Monoclonal antibody | Alzheimer’s disease | antibody-antigen complex | tau protein
Journal Article
2005, Methods In Molecular Biology, ISBN 1592598749, Volume 299
Web Resource
EBioMedicine, ISSN 2352-3964, 09/2018, Volume 35, pp. 270 - 278
Our original findings, showing the effectiveness of active and passive tau immunizations in mouse models, have now been confirmed and extended by many groups,... 
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2010, Volume 30, Issue 49, pp. 16559 - 16566
Harnessing the immune system to clear protein aggregates is emerging as a promising approach to treat various neurodegenerative diseases. In Alzheimer's... 
HYPERPHOSPHORYLATED-TAU | NEUROFIBRILLARY TANGLES | IMMUNIZATION | ALZHEIMERS-DISEASE | A-BETA | AMYLOID-PRECURSOR-PROTEIN | AXONAL-TRANSPORT | MUTANT PRESENILIN-1 | NEUROSCIENCES | AGGREGATION | TRANSGENIC MICE | Enzyme-Linked Immunosorbent Assay - methods | Immunotherapy - methods | Alzheimer Disease - complications | tau Proteins - immunology | Humans | Male | Mutation - immunology | Recognition (Psychology) - physiology | Brain - metabolism | tau Proteins - genetics | Amyloid beta-Peptides - genetics | Cognition Disorders - etiology | Amyloid beta-Peptides - metabolism | Statistics, Nonparametric | Female | Cognition Disorders - immunology | Alzheimer Disease - immunology | Peptide Fragments - genetics | Gliosis - etiology | Disease Models, Animal | Antibodies - therapeutic use | Peptide Fragments - metabolism | Maze Learning - physiology | Presenilin-1 - genetics | Behavior, Animal - physiology | Mice, Transgenic | Psychomotor Performance - drug effects | Mutation - genetics | Memory Disorders - immunology | Transcription Factors - metabolism | Motor Activity - genetics | Rotarod Performance Test | Animals | Memory Disorders - etiology | Brain - pathology | Antibodies - blood | Motor Activity - immunology | Mice | Cognition Disorders - therapy | Alzheimer Disease - genetics | Alzheimer Disease - blood | Index Medicus | Tau | Cognition | Behavior | Tangles | Immunotherapy
Journal Article
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