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The New England Journal of Medicine, ISSN 0028-4793, 05/2015, Volume 372, Issue 19, pp. 1791 - 1800
Patients with myocardial infarction 1 to 3 years previously were assigned to ticagrelor, 90 or 60 mg twice daily, or to placebo, in addition to low-dose... 
MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | CLOPIDOGREL | MANAGEMENT | ESC GUIDELINES | AMERICAN-COLLEGE | PREVENTION | ASSOCIATION TASK-FORCE | ACUTE CORONARY SYNDROMES | PRASUGREL | ASPIRIN | Purinergic P2Y Receptor Antagonists - administration & dosage | Double-Blind Method | Drug Administration Schedule | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Risk | Secondary Prevention | Adenosine - administration & dosage | Aspirin - administration & dosage | Purinergic P2Y Receptor Antagonists - adverse effects | Myocardial Infarction - drug therapy | Adenosine - adverse effects | Adenosine - analogs & derivatives | Intracranial Hemorrhages - chemically induced | Platelet Aggregation Inhibitors - administration & dosage | Cardiovascular Diseases - mortality | Female | Aged | Hemorrhage - chemically induced | Drug Therapy, Combination | Platelet Aggregation Inhibitors - adverse effects | Dose-response relationship (Biochemistry) | Treatment outcome | Care and treatment | Safety and security measures | Analysis | Dosage and administration | Ticagrelor | Heart attack | Risk factors | Myocardial infarction | Cerebral infarction | Aspirin | Stroke | Heart attacks | Hemorrhage | Long term | Patients | Thrombolysis | Bleeding | Blood platelets | Antagonist drugs | Cardiovascular diseases | Drug therapy | Life Sciences | Human health and pathology
Journal Article
by Pogue, Janice and Riddle, Matthew C and Chazova, I and Gilbert, R and Gomis, R and Pīrāgs, V and Bogaty, P and Corson, M and Harper, W.L and Cukierman-Yaffee, T and MacRae, S and Alvarez, N and Amuchastegui, M and Bello, F and Caccavo, A and Calveira, M and Camino, A and Cardone, M and Corinaldesi, F and Crespo, C and Fares Taie, A and Fernandez, A and Ferrari, N and Gutierrez, N and Hasbani, E and Hrabar, A and Lobo Marquez, L and Lugo, M and Mainini, S and Manzano, R and Mendez, N and Odetto, I and Polari, P and Ramirez, A and Sanchez, R and Smith Casabella, T and Streitenberger, P and Villamil, A and Amerena, J and Farshid, A and Lefkovits, J and O'Neal, D and Poynten, A and Simpson, R and Teede, H and Tiong, F and Waddell-Smith, K and Blocher, J and Brath, H and Breuss, J and Jankovic, V and Kann, T and Placher-Sorko, G and Sonnenfeld, M and Vetter, B and Wallner, F and Lazareva, I and Delana, J and Feitosa, G and Garcia, V and Kanedlai, N and Mothe, F and Ninno, T and Oliveira, C and Oliveira, O and Roldan, F and Bailey, A and Belanger, A and Carlson, B and Chagnon, P and Chessex, C and Crepeau, J and Dube, F and Gosselin, G and Harper, W and Ho, K and Hramiak, I and Hutchinson, A and Langlois, M and Lavoie, M and Mercier, M and Nawaz, S and O'Keefe, D and Pruneau, G and Raby, K and Richard, C and Steinson, D and VanRossum, N and Warnica, W and Galloso, R and Stockins, B and Chen, Y and Gao, X and Ji, L and Jia, W and Li, Q and Li, Y and Ling, Y and Lu, B and Peng, Y and ... and The ORIGIN Trial Investigators and ORIGIN Trial Investigators and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Centrum för klinisk forskning, Västerås
The New England Journal of Medicine, ISSN 0028-4793, 07/2012, Volume 367, Issue 4, pp. 319 - 328
In this study with a 2-by-2 factorial design, patients with cardiovascular risk factors and dysglycemia or type 2 diabetes received insulin glargine or... 
DIABETES-MELLITUS | MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | THERAPY | GLARGINE | GLUCOSE CONTROL | DISEASE | RISK | PEOPLE | ENDOTHELIAL FUNCTION | BETA-CELL FUNCTION | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Cholesterol - blood | Humans | Middle Aged | Male | Incidence | Glucose Intolerance - drug therapy | Cardiovascular Diseases - epidemiology | Female | Drug Therapy, Combination | Hypoglycemia - chemically induced | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Fasting | Blood Glucose - analysis | Double-Blind Method | Proportional Hazards Models | Hospitalization | Glucose Intolerance - complications | Insulin, Long-Acting - adverse effects | Insulin Glargine | Insulin, Long-Acting - therapeutic use | Intention to Treat Analysis | Triglycerides - blood | Fatty Acids, Omega-3 - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Type 2 diabetes | Complications and side effects | Care and treatment | Insulin glargine | Patient outcomes | Causes of | Cardiovascular diseases | Risk factors | Myocardial infarction | Fees & charges | Cerebral infarction | Medical research | Stroke | Heart attacks | Statistical analysis | Diabetes mellitus | Glucose | Hypoglycemia | Fatty acids | Insulin | Glucose tolerance | Insulin resistance | Microvasculature | Diabetes | Diabetes mellitus (non-insulin dependent) | Heart diseases | Drug dosages | Cardiovascular Diseases | Insulin, Long-Acting | Blood Glucose | Triglycerides | Glucose Intolerance | Cholesterol | Life Sciences | Hypoglycemic Agents | Diabetes Mellitus, Type 2 | Fatty Acids, Omega-3 | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
by Bosch, Jackie and Riddle, Matthew C and Rydén, Lars E and Chazova, I and Gilbert, R and Gomis, R and Pīrāgs, V and Bogaty, P and Corson, M and Harper, W.L and Cukierman-Yaffee, T and MacRae, S and Alvarez, N and Amuchastegui, M and Bello, F and Caccavo, A and Calveira, M and Camino, A and Cardone, M and Corinaldesi, F and Crespo, C and Fares Taie, A and Fernandez, A and Ferrari, N and Gutierrez, N and Hasbani, E and Hrabar, A and Lobo Marquez, L and Lugo, M and Mainini, S and Manzano, R and Mendez, N and Odetto, I and Polari, P and Ramirez, A and Sanchez, R and Smith Casabella, T and Streitenberger, P and Villamil, A and Amerena, J and Farshid, A and Lefkovits, J and O'Neal, D and Poynten, A and Simpson, R and Teede, H and Tiong, F and Waddell-Smith, K and Blocher, J and Brath, H and Breuss, J and Jankovic, V and Kann, T and Placher-Sorko, G and Sonnenfeld, M and Vetter, B and Wallner, F and Lazareva, I and Delana, J and Feitosa, G and Garcia, V and Kanedlai, N and Mothe, F and Ninno, T and Oliveira, C and Oliveira, O and Roldan, F and Bailey, A and Belanger, A and Carlson, B and Chagnon, P and Chessex, C and Crepeau, J and Dube, F and Gosselin, G and Harper, W and Ho, K and Hramiak, I and Hutchinson, A and Langlois, M and Lavoie, M and Mercier, M and Nawaz, S and O'Keefe, D and Pruneau, G and Raby, K and Richard, C and Steinson, D and VanRossum, N and Warnica, W and Galloso, R and Stockins, B and Chen, Y and Gao, X and Ji, L and Jia, W and Li, Q and Li, Y and Ling, Y and Lu, B and ... and The ORIGIN Trial Investigators and ORIGIN Trial Investigators and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Centrum för klinisk forskning, Västerås
The New England Journal of Medicine, ISSN 0028-4793, 07/2012, Volume 367, Issue 4, pp. 309 - 318
Participants with impaired fasting glucose who were at risk for cardiovascular events were assigned to receive daily n−3 fatty acids or placebo and to receive... 
MEDICINE, GENERAL & INTERNAL | EVENTS | PREVENTION | FISH | RISK | CORONARY-HEART-DISEASE | OMEGA-3-FATTY-ACID INTAKE | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Cholesterol - blood | Humans | Middle Aged | Male | Incidence | Glucose Intolerance - drug therapy | Treatment Failure | Cardiovascular Diseases - mortality | Female | Drug Therapy, Combination | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Double-Blind Method | Proportional Hazards Models | Glucose Intolerance - complications | Insulin Glargine | Insulin, Long-Acting - therapeutic use | Intention to Treat Analysis | Triglycerides - blood | Fatty Acids, Omega-3 - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Prevention | Complications and side effects | Care and treatment | Patient outcomes | Dietary supplements | Causes of | Diabetes | Cardiovascular diseases | Fatty acids | Health aspects | Myocardial infarction | Arrhythmia | Diabetes mellitus | Lipids | Esters | Cardiovascular disease | Insulin | Glucose tolerance | Diet | Death | Supplementation | Diabetes mellitus (non-insulin dependent) | Heart diseases | Cardiovascular Diseases | Insulin, Long-Acting | Triglycerides | Glucose Intolerance | Cholesterol | Life Sciences | Hypoglycemic Agents | Diabetes Mellitus, Type 2 | Fatty Acids, Omega-3 | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
PLoS medicine, ISSN 1549-1277, 2015, Volume 12, Issue 3, pp. e1001809 - e1001809
Journal Article