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1. Haemodynamic definitions and updated clinical classification of pulmonary hypertension
by Simonneau, Gérald and Montani, David and Celermajer, David S and Denton, Christopher P and Gatzoulis, Michael A and Krowka, Michael and Williams, Paul G and Souza, Rogerio
The European respiratory journal, 01/2019, Volume 53, Issue 1
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2. Full Text Updated Clinical Classification of Pulmonary Hypertension
by Simonneau, Gérald and Robbins, Ivan M and Beghetti, Maurice and Channick, Richard N and Delcroix, Marion and Denton, Christopher P and Elliott, C. Gregory and Gaine, Sean P and Gladwin, Mark T and Jing, Zhi-Cheng and Krowka, Michael J and Langleben, David and Nakanishi, Norifumi and Souza, Rogério
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2009, Volume 54, Issue 1, pp. S43 - S54
clinical classification | pulmonary arterial hypertension | pulmonary hypertension | Hypertension, Pulmonary - classification | Prognosis | Comorbidity | Humans | Calcium Channel Blockers - therapeutic use | Antihypertensive Agents - administration & dosage | Anticoagulants - therapeutic use | Treatment Outcome | Hypertension, Pulmonary - epidemiology | Evidence-Based Medicine | Scleroderma, Systemic - epidemiology | Randomized Controlled Trials as Topic | Algorithms | Hypertension, Pulmonary - drug therapy | Endothelin Receptor Antagonists | Epoprostenol - administration & dosage | Genetic counseling | Surgery | Classification | Clinical trials | Cardiovascular disease | Mutation | Family medical history | Drug therapy | Pulmonary hypertension | Defects
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3. Full Text Selexipag for the Treatment of Pulmonary Arterial Hypertension
by Sitbon, Olivier and Channick, Richard and Chin, Kelly M and Frey, Aline and Gaine, Sean and Galiè, Nazzareno and Ghofrani, Hossein-Ardeschir and Hoeper, Marius M and Lang, Irene M and Preiss, Ralph and Rubin, Lewis J and Di Scala, Lilla and Tapson, Victor and Adzerikho, Igor and Liu, Jinming and Moiseeva, Olga and Zeng, Xiaofeng and Simonneau, Gérald and McLaughlin, Vallerie V and GRIPHON Investigators
The New England journal of medicine, ISSN 0028-4793, 12/2015, Volume 373, Issue 26, pp. 2522 - 2533
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hypertension, Pulmonary - mortality | Double-Blind Method | Drug Administration Schedule | Humans | Middle Aged | Kaplan-Meier Estimate | Hospitalization - statistics & numerical data | Male | Pyrazines - therapeutic use | Disease Progression | Prodrugs - adverse effects | Acetamides - therapeutic use | Pyrazines - adverse effects | Acetamides - adverse effects | Female | Aged | Hypertension, Pulmonary - drug therapy | Prodrugs - therapeutic use | Hypertension, Pulmonary - complications | Clinical trials | Usage | Drug therapy | Pulmonary hypertension | Hypertension | Headache | Jaw | Endothelin | Pulmonary arteries | Diarrhea | Nausea | Prostacyclin | Patients | Pain | Circulatory system | Phosphodiesterase | Fees & charges | Substance abuse treatment | Statistical analysis | Committees | Drug dosages | Pharmaceuticals | Index Medicus | Abridged Index Medicus
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4. Full Text Treatment of Pulmonary Arterial Hypertension
by Humbert, Marc and Sitbon, Olivier and Simonneau, Gérald
The New England journal of medicine, ISSN 0028-4793, 09/2004, Volume 351, Issue 14, pp. 1425 - 1436
Biological and medical sciences | General aspects | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Pneumology | Hypertension, Pulmonary - mortality | Vasodilator Agents - therapeutic use | Humans | Calcium Channel Blockers - therapeutic use | Administration, Inhalation | Hypertension, Pulmonary - physiopathology | Nitric Oxide - therapeutic use | Piperazines - therapeutic use | Antihypertensive Agents - therapeutic use | Sildenafil Citrate | Epoprostenol - therapeutic use | Purines | Epoprostenol - analogs & derivatives | Diuretics - therapeutic use | Iloprost - therapeutic use | Hypertension, Pulmonary - drug therapy | Infusions, Intravenous | Drug Therapy, Combination | Endothelin Receptor Antagonists | Sulfones | Care and treatment | Pulmonary hypertension | Diagnosis | Hypertension | Proteins | Drug therapy | Pulmonary arteries | Index Medicus | Abridged Index Medicus
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5. Full Text Reply to frachon
by Simonneau, Gérald and Humbert, Marc
American journal of respiratory and critical care medicine, ISSN 1073-449X, 05/2018, Volume 197, Issue 10, pp. 1364 - 1365
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6. Full Text Reply to Frachon: Amphetamine Derivatives and the Risk of Pulmonary Arterial Hypertension: A Missing Chapter of the Story?
by Simonneau, Gérald and Humbert, Marc
American journal of respiratory and critical care medicine, ISSN 1073-449X, 05/2018, Volume 197, Issue 10, pp. 1364 - 1365
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7. Full Text EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension
by Eyries, Mélanie and Montani, David and Girerd, Barbara and Perret, Claire and Leroy, Anne and Lonjou, Christine and Chelghoum, Nadjim and Coulet, Florence and Bonnet, Damien and Dorfmüller, Peter and Fadel, Elie and Sitbon, Olivier and Simonneau, Gérald and Tregouët, David-Alexandre and Humbert, Marc and Soubrier, Florent
Nature genetics, ISSN 1061-4036, 01/2014, Volume 46, Issue 1, pp. 65 - 69
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Pulmonary Veno-Occlusive Disease - physiopathology | Humans | Middle Aged | Protein-Serine-Threonine Kinases - genetics | Hypertension, Pulmonary - physiopathology | Male | Chromosome Mapping | Young Adult | Homozygote | Pulmonary Veno-Occlusive Disease - genetics | Pedigree | Adult | Female | Mutation | Protein-Serine-Threonine Kinases - metabolism | Causes of | Physiological aspects | Genetic aspects | Research | Gene mutations | Pulmonary hypertension | Studies | Genetic counseling | Genes | Tomography | Software | Genomes | Kinases | Experiments | Siblings | Index Medicus | Life Sciences | Biochemistry, Molecular Biology | Genomics
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8. Full Text Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension
by Guignabert, Christophe and Phan, Carole and Seferian, Andrei and Huertas, Alice and Tu, Ly and Thuillet, Raphaël and Sattler, Caroline and Hiress, Morane Le and Tamura, Yuichi and Jutant, Etienne-Marie and Chaumais, Marie-Camille and Bouchet, Stéphane and Manéglier, Benjamin and Molimard, Mathieu and Rousselot, Philippe and Sitbon, Olivier and Simonneau, Gérald and Montani, David and Humbert, Marc
The Journal of clinical investigation, ISSN 0021-9738, 09/2016, Volume 126, Issue 9, pp. 3207 - 3218
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | E-Selectin - blood | Male | Hypertension, Pulmonary - chemically induced | Hypoxia - metabolism | Antineoplastic Agents - adverse effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Adult | Female | Intercellular Adhesion Molecule-1 - blood | Antineoplastic Agents - pharmacology | Genetic Predisposition to Disease | Imatinib Mesylate - pharmacology | Cells, Cultured | Rats | Mitochondria - metabolism | Vascular Cell Adhesion Molecule-1 - blood | Dasatinib - pharmacology | Animals | Lung - drug effects | Dasatinib - adverse effects | Hemodynamics | Lung - blood supply | Apoptosis | Dasatinib | Research | Health aspects | Pulmonary hypertension | Risk factors | Scholarships & fellowships | Toxicity | Mortality | Rodents | Leukemia | Hypoxia | Grants | Laboratory animals | Experiments | Drug dosages | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Cellular Biology | Cardiology and cardiovascular system | Pulmonology and respiratory tract
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9. Full Text Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial
by Simonneau, Gérald and Rubin, Lewis J and Galiè, Nazzareno and Barst, Robyn J and Fleming, Thomas R and Frost, Adaani E and Engel, Peter J and Kramer, Mordechai R and Burgess, Gary and Collings, Lorraine and Cossons, Nandini and Sitbon, Olivier and Badesch, David B and PACES Study Grp and PACES Study Group
Annals of internal medicine, ISSN 0003-4819, 10/2008, Volume 149, Issue 8, pp. 521 - 530
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Pneumology | Piperazines - administration & dosage | Injections, Intravenous | Humans | Middle Aged | Sulfones - adverse effects | Antihypertensive Agents - administration & dosage | Hypertension, Pulmonary - physiopathology | Male | Dyspepsia - chemically induced | Purines - administration & dosage | Hemodynamics - physiology | Walking - physiology | Sildenafil Citrate | Time Factors | Epoprostenol - adverse effects | Adult | Female | Hypertension, Pulmonary - drug therapy | Purines - adverse effects | Drug Therapy, Combination | Headache - chemically induced | Double-Blind Method | Administration, Oral | Piperazines - adverse effects | Antihypertensive Agents - adverse effects | Adolescent | Quality of Life | Aged | Vasodilator Agents - adverse effects | Hypertension, Pulmonary - etiology | Vasodilator Agents - administration & dosage | Epoprostenol - administration & dosage | Sulfones - administration & dosage | Complications and side effects | Epoprostenol | Dosage and administration | Sildenafil | Drug therapy, Combination | Research | Drug therapy | Pulmonary hypertension | Hypertension | Inhibitor drugs | Patients | Quality of life | Index Medicus | Abridged Index Medicus
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10. Full Text Initial combination therapy with ambrisentan and tadalafil in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH): subgroup analysis from the AMBITION trial
by Coghlan, John Gerry and Galiè, Nazzareno and Barberà, Joan Albert and Frost, Adaani E and Ghofrani, Hossein-Ardeschir and Hoeper, Marius M and Kuwana, Masataka and McLaughlin, Vallerie V and Peacock, Andrew J and Simonneau, Gérald and Vachiéry, Jean-Luc and Blair, Christiana and Gillies, Hunter and Miller, Karen L and Harris, Julia H N and Langley, Jonathan and Rubin, Lewis J and AMBITION Investigators and AMBITION investigators
Annals of the rheumatic diseases, ISSN 0003-4967, 07/2017, Volume 76, Issue 7, pp. 1219 - 1227
Systemic Sclerosis | Arterial Hypertension | Treatment | Life Sciences & Biomedicine | Rheumatology | Science & Technology | Lupus Erythematosus, Systemic - complications | Double-Blind Method | Humans | Middle Aged | Male | Antihypertensive Agents - therapeutic use | Disease Progression | Phenylpropionates - therapeutic use | Mixed Connective Tissue Disease - complications | Scleroderma, Systemic - complications | Adult | Female | Aged | Hypertension, Pulmonary - drug therapy | Phosphodiesterase 5 Inhibitors - therapeutic use | Edema - chemically induced | Drug Therapy, Combination | Tadalafil - therapeutic use | Hypertension, Pulmonary - etiology | Pyridazines - therapeutic use | Tadalafil | Usage | Care and treatment | Analysis | Clinical trials | Drug therapy, Combination | Research | Pulmonary hypertension | Heart | Hypertension | Edema | Laboratories | Pulmonary arteries | Mortality | Lung diseases | Cardiovascular disease | Studies | Systemic sclerosis | Medical prognosis | Population | Health risk assessment | Scleroderma | Index Medicus | Clinical and Epidemiological Research | 1506
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11. Full Text Amphetamine Derivatives and the Risk of Pulmonary Arterial Hypertension A New Chapter of the Story
by Simonneau, Gerald and Humbert, Marc
American journal of respiratory and critical care medicine, ISSN 1073-449X, 03/2018, Volume 197, Issue 6, pp. 704 - 706
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary | Amphetamine | Humans | Methamphetamine | Drugs | Anorexia | Pulmonary arteries | Medical prognosis | Mutation | Health risk assessment | Pulmonary hypertension
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