Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (436) 436
Patent (120) 120
Book Chapter (13) 13
Conference Proceeding (4) 4
Book / eBook (2) 2
Book Review (2) 2
Reference (2) 2
Dissertation (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (239) 239
life sciences & biomedicine (222) 222
animals (210) 210
rats (151) 151
biological and medical sciences (137) 137
female (127) 127
human necessities (102) 102
neurosciences & neurology (97) 97
humans (94) 94
neurosciences (91) 91
hygiene (88) 88
medical or veterinary science (88) 88
preparations for medical, dental, or toilet purposes (88) 88
medical sciences (85) 85
estradiol - pharmacology (67) 67
chemistry (66) 66
rats, sprague-dawley (64) 64
fundamental and applied biological sciences. psychology (63) 63
male (61) 61
specific therapeutic activity of chemical compounds ormedicinal preparations (57) 57
neurology (54) 54
neuroprotection (53) 53
estrogen (52) 52
organic chemistry (52) 52
metallurgy (51) 51
steroids (47) 47
pharmacology. drug treatments (44) 44
estradiol (43) 43
estrogens (40) 40
neuroprotective agents - pharmacology (39) 39
pharmacology & pharmacy (39) 39
estrogens - pharmacology (35) 35
stroke (35) 35
brain - metabolism (34) 34
alzheimer's disease (33) 33
mice (33) 33
ovariectomy (33) 33
neurons - drug effects (30) 30
endocrinology & metabolism (28) 28
rats, inbred strains (28) 28
vertebrates: endocrinology (28) 28
dose-response relationship, drug (27) 27
mitochondria (27) 27
ischemia (26) 26
biochemistry & molecular biology (25) 25
analysis (23) 23
brain (23) 23
cell survival - drug effects (23) 23
time factors (23) 23
brain - drug effects (22) 22
cells, cultured (22) 22
disease models, animal (22) 22
neuropharmacology (22) 22
vascular diseases and vascular malformations of the nervous system (21) 21
mitochondria - metabolism (20) 20
neurons - metabolism (20) 20
physics (20) 20
clinical neurology (19) 19
estradiol - administration & dosage (19) 19
measuring (19) 19
testing (19) 19
17β-estradiol (18) 18
abridged index medicus (18) 18
blood-brain barrier (18) 18
hypothalamus. hypophysis. epiphysis. urophysis (18) 18
morphine - pharmacology (18) 18
oxidative stress (18) 18
apoptosis (17) 17
cell line (17) 17
estrogens - metabolism (17) 17
general tagging of cross-sectional technologies spanning over several sections of the ipc (17) 17
general tagging of new technological developments (17) 17
hormones and neuropeptides. regulation (17) 17
physical sciences (17) 17
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (17) 17
toxicology (17) 17
agriculture (16) 16
cell death - drug effects (16) 16
geriatrics & gerontology (16) 16
oxidative stress - drug effects (16) 16
research (16) 16
vertebrates: nervous system and sense organs (16) 16
estradiol - blood (15) 15
estradiol - therapeutic use (15) 15
naloxone - pharmacology (15) 15
neurons (15) 15
proteins (15) 15
alzheimer’s disease (14) 14
animal husbandry (14) 14
apparatus for making beverages (14) 14
biocides, e.g. as disinfectants, as pesticides, as herbicides (14) 14
coffee mills (14) 14
domestic articles or appliances (14) 14
ethanol withdrawal (14) 14
fishing (14) 14
forestry (14) 14
furniture (14) 14
hunting (14) 14
kitchen equipment (14) 14
measuring volume, volume flow, mass flow or liquidlevel (14) 14
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an -glucosidase inhibitor or a Nrf2-inducer
by Strong, Randy and Miller, Richard A and Antebi, Adam and Astle, Clinton M and Bogue, Molly and Denzel, Martin S and Fernandez, Elizabeth and Flurkey, Kevin and Hamilton, Karyn L and Lamming, Dudley W and Javors, Martin A and de Magalhaes, Joao Pedro and Martinez, Paul Anthony and McCord, Joe M and Miller, Benjamin F and Muller, Michael and Nelson, James F and Ndukum, Juliet and Rainger, G. Ed and Richardson, Arlan and Sabatini, David M and Salmon, Adam B and Simpkins, James W and Steegenga, Wilma T and Nadon, Nancy L and Harrison, David E
Aging cell, ISSN 1474-9718, 10/2016, Volume 15, Issue 5, pp. 872 - 884
Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Cell Biology | Antioxidants | Ursodiol | Dosage and administration | Estradiol
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Blood substitution therapy rescues the brain of mice from ischemic damage
by Ren, Xuefang and Hu, Heng and Farooqi, Imran and Simpkins, James W
Nature communications, ISSN 2041-1723, 08/2020, Volume 11, Issue 1, pp. 4078 - 4078
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Occlusion | Therapy | Stroke | Animal models | Matrix metalloproteinases | Cytokines | Leukocytes (neutrophilic) | Matrix metalloproteinase | Electrochemiluminescence | Cytokine storm | Blood | Gelatinase B | Neurological diseases | Ischemia | Cerebral blood flow | Brain damage | Metalloproteinase | Immune system | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text An okadaic acid-induced model of tauopathy and cognitive deficiency
by Zhang, Zhang and Simpkins, James W
Brain research, ISSN 0006-8993, 2010, Volume 1359, pp. 233 - 246
Neurology | Tau phosphorylation | Oxidative stress | Neurofibrillary tangles | Tauopathy | Alzheimer's disease | Cognitive deficiency | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Organic mental disorders. Neuropsychology | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Psychopathology. Psychiatry | Biological and medical sciences | Medical sciences | Immunohistochemistry | Phosphorylation | Cognition Disorders - chemically induced | Oxidative Stress - physiology | Injections, Intraventricular | Tauopathies - pathology | Alzheimer Disease - pathology | Okadaic Acid - administration & dosage | Brain - metabolism | Enzyme Inhibitors - administration & dosage | Neurofibrillary Tangles - metabolism | Enzyme Inhibitors - toxicity | Female | Okadaic Acid - toxicity | Disease Models, Animal | Neurofibrillary Tangles - pathology | Ovariectomy | Cognition Disorders - pathology | Rats | Maze Learning - drug effects | Rats, Sprague-Dawley | Blotting, Western | Brain - drug effects | Tauopathies - metabolism | Animals | Alzheimer Disease - metabolism | Brain - pathology | Oxidative Stress - drug effects | Phosphatases | Synthesis | Glycogen | Analysis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Sequential upregulation of superoxide dismutase 2 and heme oxygenase 1 by tert-butylhydroquinone protects mitochondria during oxidative stress
by Sun, Jiahong and Ren, Xuefang and Simpkins, James W
Molecular pharmacology, ISSN 0026-895X, 09/2015, Volume 88, Issue 3, pp. 437 - 449
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cell Line | Up-Regulation | Heme Oxygenase-1 - metabolism | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Oxidative Stress | Cells, Cultured | Rats | Mitochondria - metabolism | Mitochondria - drug effects | Hydroquinones - pharmacology | Rats, Sprague-Dawley | Heme Oxygenase-1 - genetics | Animals | Neuroprotective Agents - pharmacology | Mice | Neurons - metabolism | Glutamic Acid - toxicity | Neurons - drug effects | Superoxide Dismutase - metabolism | Apoptosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Rapid mitochondrial dysfunction mediates TNF‐alpha‐induced neurotoxicity
by Doll, Danielle N and Rellick, Stephanie L and Barr, Taura L and Ren, Xuefang and Simpkins, James W
Journal of neurochemistry, ISSN 0022-3042, 02/2015, Volume 132, Issue 4, pp. 443 - 451
neuro‐toxicity | cytokines | inflammation | TNF‐alpha | stroke | mitochondria | neuro-toxicity | TNF-alpha | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cell Survival - drug effects | Animals | Time Factors | Mice | Hippocampus - drug effects | Mitochondria - drug effects | Hippocampus - cytology | Hippocampus - physiology | Mitochondria - physiology | Tumor Necrosis Factor-alpha - toxicity | Cell Line, Transformed | Cell Survival - physiology | Brain | Mitochondrial DNA | Tumor necrosis factor | Analysis | Injuries | Neurochemistry | Mitochondria | Neurotoxicity | Cytokines | Immune system | Index Medicus | neurotoxicity
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Paper-Based Surface-Enhanced Raman Scattering Lateral Flow Strip for Detection of Neuron-Specific Enolase in Blood Plasma
by Gao, Xuefei and Zheng, Peng and Kasani, Sujan and Wu, Steven and Yang, Feng and Lewis, Sara and Nayeem, Sara and Engler-Chiurazzi, Elizabeth B and Wigginton, Jane G and Simpkins, James W and Wu, Nianqiang
Analytical chemistry (Washington), ISSN 0003-2700, 09/2017, Volume 89, Issue 18, pp. 10104 - 10110
Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Brain | Usage | Cellular signal transduction | Research | Injuries | Raman effect | Plasma | Raman spectra | Immunoassay | Gold | Traumatic brain injury | Neurons | Scattering | Colorimetry | Patients | Silica | Blood | Silicon dioxide | Blood plasma | Nanoparticles | Sensitivity | Dilution | Matrix | Head injuries | Biomarkers | Phosphopyruvate hydratase | Plasmas (physics) | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Mitochondrial mechanisms of estrogen neuroprotection
by Simpkins, James W and Yi, Kun Don and Yang, Shao-Hua and Dykens, James A
Biochimica et biophysica acta. General subjects, ISSN 0304-4165, 10/2010, Volume 1800, Issue 10, pp. 1113 - 1120
Estrogen receptor | Neuroprotection | Mitochondria | Estrogen | Non-feminizing estrogens | Alzheimer's disease | Estradiol | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Neuroprotective Agents - therapeutic use | Cell Survival - drug effects | Neurons - pathology | Brain Injuries - drug therapy | Humans | Mitochondria - metabolism | Brain Injuries - metabolism | Mitochondria - pathology | Estrogens - therapeutic use | Animals | Alzheimer Disease - prevention & control | Alzheimer Disease - metabolism | Neurons - metabolism | Cell Death - drug effects | Oxidative Stress - drug effects | Brain Injuries - pathology | Chronic Disease | Neurosciences | Nervous system diseases | Neurons | Phenols | Mitochondrial DNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Estrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1
by Sarkar, Saumyendra and Jun, Sujung and Simpkins, James W
Brain research, ISSN 0006-8993, 2015, Volume 1616, pp. 101 - 111
Neurology | Estrogen receptor β | Mitochondrial Movement | Alzheimer׳s disease | Mitochondrial Fission And Fusion | PKA | AKAP1 | Alzheimer's disease | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Dendrites - drug effects | Brain - cytology | Dynamins - metabolism | Estrogens - pharmacology | Embryo, Mammalian | Amyloid beta-Peptides - pharmacology | Humans | Cells, Cultured | Rats | Peptide Fragments - pharmacology | Dendrites - ultrastructure | Mitochondria - drug effects | Estrogen Receptor beta - metabolism | A Kinase Anchor Proteins - genetics | Animals | Estrogen Receptor beta - genetics | Neurons - ultrastructure | Transfection | Signal Transduction - drug effects | Mitochondrial Proteins - metabolism | A Kinase Anchor Proteins - metabolism | Index Medicus | mitochondrial fission and fusion | Alzheimer’s disease | mitochondrial movement
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system
by Sprenkle, Neil T and Lahiri, Anirudhya and Simpkins, James W and Meares, Gordon P
Journal of neurochemistry, ISSN 0022-3042, 02/2019, Volume 148, Issue 4, pp. 516 - 530
ER stress | unfolded protein response | astrocytes | inflammation | neurons | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Astrocytes - drug effects | Mice, Inbred C57BL | Cells, Cultured | Cell Communication - physiology | Culture Media, Conditioned - pharmacology | Brain - physiology | Astrocytes - physiology | Animals | Neurons - physiology | Mice | Neurons - drug effects | Unfolded Protein Response - physiology | Endoplasmic Reticulum Stress - physiology | Proteins | Physiological aspects | Nervous system diseases | Central nervous system | Neurodegenerative diseases | Neurons | Astrocytes | Cytotoxicity | Nervous system | Lipids | Exposure | Inflammation | Resistance factors | Stress | Microglia | Neurological diseases | Neurotoxicity | Protein folding | Conditioning | Protein transport | Endoplasmic reticulum | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights