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The New England journal of medicine, ISSN 1533-4406, 2013, Volume 369, Issue 22, pp. 2093 - 2104
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2015, Volume 372, Issue 19, pp. 1791 - 1800
Patients with myocardial infarction 1 to 3 years previously were assigned to ticagrelor, 90 or 60 mg twice daily, or to placebo, in addition to low-dose... 
MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | CLOPIDOGREL | MANAGEMENT | ESC GUIDELINES | AMERICAN-COLLEGE | PREVENTION | ASSOCIATION TASK-FORCE | ACUTE CORONARY SYNDROMES | PRASUGREL | ASPIRIN | Purinergic P2Y Receptor Antagonists - administration & dosage | Double-Blind Method | Drug Administration Schedule | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Risk | Secondary Prevention | Adenosine - administration & dosage | Aspirin - administration & dosage | Purinergic P2Y Receptor Antagonists - adverse effects | Myocardial Infarction - drug therapy | Adenosine - adverse effects | Adenosine - analogs & derivatives | Intracranial Hemorrhages - chemically induced | Platelet Aggregation Inhibitors - administration & dosage | Cardiovascular Diseases - mortality | Female | Aged | Hemorrhage - chemically induced | Drug Therapy, Combination | Platelet Aggregation Inhibitors - adverse effects | Dose-response relationship (Biochemistry) | Treatment outcome | Care and treatment | Safety and security measures | Analysis | Dosage and administration | Ticagrelor | Heart attack | Risk factors | Myocardial infarction | Cerebral infarction | Aspirin | Stroke | Heart attacks | Hemorrhage | Long term | Patients | Thrombolysis | Bleeding | Blood platelets | Antagonist drugs | Cardiovascular diseases | Drug therapy | Life Sciences | Human health and pathology
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2015, Volume 372, Issue 25, pp. 2387 - 2397
In this trial, patients with an acute coronary syndrome within the previous 10 days were randomly assigned to simvastatin plus either ezetimibe or placebo. At... 
no | CHOLESTEROL ABSORPTION | CARDIAC OUTCOMES | MEDICINE, GENERAL & INTERNAL | MYOCARDIAL-INFARCTION | EFFICACY | CARDIOVASCULAR OUTCOMES | CLINICAL-TRIALS | SIMVASTATIN | PRIMARY PREVENTION | IMPROVE-IT | ATORVASTATIN | Simvastatin - therapeutic use | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Azetidines - adverse effects | Ezetimibe | Kaplan-Meier Estimate | Male | Anticholesteremic Agents - adverse effects | Acute Coronary Syndrome - drug therapy | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Usage | Simvastatin | Analysis | Practice guidelines (Medicine) | Dosage and administration | Drug therapy, Combination | Acute coronary syndrome | Drug therapy | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Angina | Cholesterol | Intestine | Gallbladder | Acute coronary syndromes | Cardiovascular diseases | Statins | Pharmaceuticals | Cancer | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
Journal Article
by Pogue, Janice and Riddle, Matthew C and Chazova, I and Gilbert, R and Gomis, R and Pīrāgs, V and Bogaty, P and Corson, M and Harper, W.L and Cukierman-Yaffee, T and MacRae, S and Alvarez, N and Amuchastegui, M and Bello, F and Caccavo, A and Calveira, M and Camino, A and Cardone, M and Corinaldesi, F and Crespo, C and Fares Taie, A and Fernandez, A and Ferrari, N and Gutierrez, N and Hasbani, E and Hrabar, A and Lobo Marquez, L and Lugo, M and Mainini, S and Manzano, R and Mendez, N and Odetto, I and Polari, P and Ramirez, A and Sanchez, R and Smith Casabella, T and Streitenberger, P and Villamil, A and Amerena, J and Farshid, A and Lefkovits, J and O'Neal, D and Poynten, A and Simpson, R and Teede, H and Tiong, F and Waddell-Smith, K and Blocher, J and Brath, H and Breuss, J and Jankovic, V and Kann, T and Placher-Sorko, G and Sonnenfeld, M and Vetter, B and Wallner, F and Lazareva, I and Delana, J and Feitosa, G and Garcia, V and Kanedlai, N and Mothe, F and Ninno, T and Oliveira, C and Oliveira, O and Roldan, F and Bailey, A and Belanger, A and Carlson, B and Chagnon, P and Chessex, C and Crepeau, J and Dube, F and Gosselin, G and Harper, W and Ho, K and Hramiak, I and Hutchinson, A and Langlois, M and Lavoie, M and Mercier, M and Nawaz, S and O'Keefe, D and Pruneau, G and Raby, K and Richard, C and Steinson, D and VanRossum, N and Warnica, W and Galloso, R and Stockins, B and Chen, Y and Gao, X and Ji, L and Jia, W and Li, Q and Li, Y and Ling, Y and Lu, B and Peng, Y and ... and unav and The ORIGIN Trial Investigators and ORIGIN Trial Investigators
The New England journal of medicine, ISSN 1533-4406, 2012, Volume 367, Issue 4, pp. 319 - 328
In this study with a 2-by-2 factorial design, patients with cardiovascular risk factors and dysglycemia or type 2 diabetes received insulin glargine or... 
DIABETES-MELLITUS | MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | THERAPY | GLARGINE | GLUCOSE CONTROL | DISEASE | RISK | PEOPLE | ENDOTHELIAL FUNCTION | BETA-CELL FUNCTION | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Cholesterol - blood | Humans | Middle Aged | Male | Incidence | Glucose Intolerance - drug therapy | Cardiovascular Diseases - epidemiology | Female | Drug Therapy, Combination | Hypoglycemia - chemically induced | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Fasting | Blood Glucose - analysis | Double-Blind Method | Proportional Hazards Models | Hospitalization | Glucose Intolerance - complications | Insulin, Long-Acting - adverse effects | Insulin Glargine | Insulin, Long-Acting - therapeutic use | Intention to Treat Analysis | Triglycerides - blood | Fatty Acids, Omega-3 - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Type 2 diabetes | Complications and side effects | Care and treatment | Insulin glargine | Patient outcomes | Causes of | Cardiovascular diseases | Risk factors | Myocardial infarction | Fees & charges | Cerebral infarction | Medical research | Stroke | Heart attacks | Statistical analysis | Diabetes mellitus | Glucose | Hypoglycemia | Fatty acids | Insulin | Glucose tolerance | Insulin resistance | Microvasculature | Diabetes | Diabetes mellitus (non-insulin dependent) | Heart diseases | Drug dosages | Cardiovascular Diseases | Insulin, Long-Acting | Blood Glucose | Triglycerides | Glucose Intolerance | Cholesterol | Life Sciences | Hypoglycemic Agents | Diabetes Mellitus, Type 2 | Fatty Acids, Omega-3
Journal Article
by Bosch, Jackie and Riddle, Matthew C and Rydén, Lars E and Chazova, I and Gilbert, R and Gomis, R and Pīrāgs, V and Bogaty, P and Corson, M and Harper, W.L and Cukierman-Yaffee, T and MacRae, S and Alvarez, N and Amuchastegui, M and Bello, F and Caccavo, A and Calveira, M and Camino, A and Cardone, M and Corinaldesi, F and Crespo, C and Fares Taie, A and Fernandez, A and Ferrari, N and Gutierrez, N and Hasbani, E and Hrabar, A and Lobo Marquez, L and Lugo, M and Mainini, S and Manzano, R and Mendez, N and Odetto, I and Polari, P and Ramirez, A and Sanchez, R and Smith Casabella, T and Streitenberger, P and Villamil, A and Amerena, J and Farshid, A and Lefkovits, J and O'Neal, D and Poynten, A and Simpson, R and Teede, H and Tiong, F and Waddell-Smith, K and Blocher, J and Brath, H and Breuss, J and Jankovic, V and Kann, T and Placher-Sorko, G and Sonnenfeld, M and Vetter, B and Wallner, F and Lazareva, I and Delana, J and Feitosa, G and Garcia, V and Kanedlai, N and Mothe, F and Ninno, T and Oliveira, C and Oliveira, O and Roldan, F and Bailey, A and Belanger, A and Carlson, B and Chagnon, P and Chessex, C and Crepeau, J and Dube, F and Gosselin, G and Harper, W and Ho, K and Hramiak, I and Hutchinson, A and Langlois, M and Lavoie, M and Mercier, M and Nawaz, S and O'Keefe, D and Pruneau, G and Raby, K and Richard, C and Steinson, D and VanRossum, N and Warnica, W and Galloso, R and Stockins, B and Chen, Y and Gao, X and Ji, L and Jia, W and Li, Q and Li, Y and Ling, Y and Lu, B and ... and The ORIGIN Trial Investigators and ORIGIN Trial Investigators
The New England journal of medicine, ISSN 1533-4406, 2012, Volume 367, Issue 4, pp. 309 - 318
Participants with impaired fasting glucose who were at risk for cardiovascular events were assigned to receive daily n−3 fatty acids or placebo and to receive... 
MEDICINE, GENERAL & INTERNAL | EVENTS | PREVENTION | FISH | RISK | CORONARY-HEART-DISEASE | OMEGA-3-FATTY-ACID INTAKE | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Cholesterol - blood | Humans | Middle Aged | Male | Incidence | Glucose Intolerance - drug therapy | Treatment Failure | Cardiovascular Diseases - mortality | Female | Drug Therapy, Combination | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Double-Blind Method | Proportional Hazards Models | Glucose Intolerance - complications | Insulin Glargine | Insulin, Long-Acting - therapeutic use | Intention to Treat Analysis | Triglycerides - blood | Fatty Acids, Omega-3 - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Prevention | Complications and side effects | Care and treatment | Patient outcomes | Dietary supplements | Causes of | Diabetes | Cardiovascular diseases | Fatty acids | Health aspects | Myocardial infarction | Arrhythmia | Diabetes mellitus | Lipids | Esters | Cardiovascular disease | Insulin | Glucose tolerance | Diet | Death | Supplementation | Diabetes mellitus (non-insulin dependent) | Heart diseases | Cardiovascular Diseases | Insulin, Long-Acting | Triglycerides | Glucose Intolerance | Cholesterol | Life Sciences | Hypoglycemic Agents | Diabetes Mellitus, Type 2 | Fatty Acids, Omega-3
Journal Article