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Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 1, pp. 88 - 99
Background & Aims Categorization of colon cancers into distinct subtypes using a combination of pathway-based biomarkers could provide insight into... 
Gastroenterology and Hepatology | Colorectal Cancer | Genetics | Oncogene | Prognostic Factor | ADJUVANT CHEMOTHERAPY | BRAF MUTATION STATUS | TRIAL CALGB 89803 | RANDOMIZED-TRIAL | V600E MUTATION | MICROSATELLITE-INSTABILITY | KRAS-MUTATION | COLORECTAL-CANCER | RAS MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | MISMATCH-REPAIR STATUS | MutL Protein Homolog 1 | Predictive Value of Tests | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | Adenocarcinoma - pathology | Colonic Neoplasms - classification | Prospective Studies | Adenocarcinoma - classification | Humans | Middle Aged | DNA-Binding Proteins - analysis | Male | Young Adult | Time Factors | DNA Mismatch Repair | Aged, 80 and over | Colonic Neoplasms - therapy | Genetic Predisposition to Disease | Risk Factors | Adaptor Proteins, Signal Transducing - analysis | Phenotype | Adenocarcinoma - therapy | Biomarkers, Tumor - genetics | Mutation | ras Proteins - genetics | Nuclear Proteins - analysis | DNA Mutational Analysis - methods | DNA Methylation | Polymerase Chain Reaction | Adult | Female | Adenocarcinoma - genetics | Nuclear Proteins - genetics | Promoter Regions, Genetic | Colonic Neoplasms - mortality | Reproducibility of Results | Biomarkers, Tumor - analysis | Kaplan-Meier Estimate | Proportional Hazards Models | Proto-Oncogene Proteins - genetics | Treatment Outcome | Disease-Free Survival | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | Adaptor Proteins, Signal Transducing - genetics | Aged | MutS Homolog 2 Protein - analysis | Neoplasm Staging | Adenocarcinoma - mortality | Cancer patients | Patient outcomes | Colon cancer | Index Medicus | Abridged Index Medicus | colorectal cancer | genetics | prognostic factor | oncogene
Journal Article
by Thrift, Aaron P and Shaheen, Nicholas J and Gammon, Marilie D and Bernstein, Leslie and Reid, Brian J and Onstad, Lynn and Risch, Harvey A and Liu, Geoffrey and Bird, Nigel C and Wu, Anna H and Corley, Douglas A and Romero, Yvonne and Chanock, Stephen J and Chow, Wong-Ho and Casson, Alan G and Levine, David M and Zhang, Rui and Ek, Weronica E and MacGregor, Stuart and Ye, Weimin and Hardie, Laura J and Vaughan, Thomas L and Whiteman, David C and Achem, Sami R and Ahlquist, David A and Alberts, Steven R and Alexander, Jeffrey A and Allen, Mark S and Arora, Amindra S and Ashman, Jonathan B and Atherton, Pamela J and Boardman, Lisa A and Bouras, Ernest P and Bryhn, Vicki A and Burch, Patrick A and Burdick, George E and Buttar, Navtej S and Camoriano, John K and Cangemi, John R and Cassivi, Stephen D and Cayer, Frances K and Clayton, Amy C and Crowell, Michael D and Cunningham, Julie M and De Andrade, Mariza and De Groen, Piet and De Petris, Giovani and Deschamps, Claude and DeVault, Kenneth R and Diasio, Robert B and DiBaise, John K and Edell, Eric S and Elcombe, Sharon and Erlichman, Charles and Faigel, Douglas O and Fitch, Tom R and Fleischer, David E and Fox, Jean C and Foxx-Orenstein, Amy E and Francis, Dawn and Fredericksen, Mary B and Galanis, Evanthia and Geno, Debra M and Grothey, Axel and Haddock, Michael G and Halling, Kevin C and Harnois, Denise M and Hilton, Tracy W and Hobday, Timothy and Houghton, Lesley A and Iyer, Prasad A and Jaroszewski, Dawn E and Jatoi, Aminah and Jenkins, Robert B and Johnson, Elizabeth A and Katipamula, Rajni and Katzka, David A and Kaufman, Sharon F and Keaveny, Andrew P and Keller, Daniel A and Kim, George P and Kipp, Benjamin R and Lam-Himlin, Dora M and Lange, Stephen M and Lanza, Louis and Legrand, Shauna N and Limburg, Paul J and Lingle, Wilma L and Liu, Wanguo and Locke, G. Richard and Loeb, David S and Lutzke, Lori S and Martenson, James A and McWilliams, Robert R and Miller, Robert C and Murray, Joseph A and Nguyen, Cuong C and Nichols, Francis C and Odell, John A and Pannala, Rahul and ...
Journal of the National Cancer Institute, ISSN 0027-8874, 11/2014, Volume 106, Issue 11, p. 1
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 05/2016, Volume 34, Issue 15, pp. 3600 - 3600
Conference Proceeding
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 05/2016, Volume 34, Issue 15, pp. 3518 - 3518
Conference Proceeding
by Berger, Ashton C and Korkut, Anil and Kanchi, Rupa S and Hegde, Apurva M and Lenoir, Walter and Liu, Xiuping and Liu, Wenbin and Liu, Yuexin and Liu, Liang and Liu, Jia and Fan, Cheng and Fan, Huihui and Shen, Hui and Ravikumar, Visweswaran and Rao, Arvind and Schultz, Andre and Schultz, Nikolaus and Li, Xubin and Li, Wei and Li, Jun and Sumazin, Pavel and Williams, Felicia and Williams, Cecilia and Mestdagh, Pieter and Gunaratne, Preethi H and Yau, Christina and Bowlby, Reanne and Robertson, A. Gordon and Tiezzi, Daniel G and Wang, Zhining and Wang, Min and Wang, Jing and Wang, Linghua and Wang, Jioajiao and Wang, Timothy and Wang, Chen and Cherniack, Andrew D and Godwin, Eryn M and Godwin, Andrew K and Kuderer, Nicole M and Rader, Janet S and Zuna, Rosemary and Zuna, Rosemary E and Sood, Anil K and Sood, Anil and Lazar, Alexander J and Ojesina, Akinyemi I and Adebamowo, Clement and Adebamowo, Sally N and Baggerly, Keith A and Chen, Amy and Chen, Chu and Chen, Ting-Wen and Chiu, Hua-Sheng and Lefever, Steve and MacKenzie, Karen and Orsulic, Sandra and Roszik, Jason and Shelley, Carl Simon and Song, Qianqian and Vellano, Christopher P and Wentzensen, Nicolas and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Hannah and Yang, Liming and Yang, Ian and Yang, Ju Dong and Zenklusen, Jean C and Zhang, Wei and Zhang, Hongxin and Zhang, Hailei and Zhang, Jiashan (Julia) and Zhang, Lizhi and Zhang, Jiexin and Zhang, Hongzheng and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS) and Proteomik och nanobioteknologi and Cellulär och klinisk proteomik and Skolan för bioteknologi (BIO) and Proteinvetenskap and KTH and Skolan för kemi, bioteknologi och hälsa (CBH)
Cancer Cell, ISSN 1535-6108, 04/2018, Volume 33, Issue 4, pp. 690 - 705.e9
Journal Article
JAMA Oncology, ISSN 2374-2437, 04/2017, Volume 3, Issue 4, pp. 472 - 480
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 05/2018, Volume 36, Issue 15, pp. 3583 - 3583
Conference Proceeding
JAMA Oncology, ISSN 2374-2437, 03/2018, Volume 4, Issue 3, pp. 379 - 383
IMPORTANCE The prognostic impact of DNA mismatch repair (MMR) status in stage III colon cancer patients receiving FOLFOX (folinic acid, fluorouracil, and... 
SURVIVAL | CETUXIMAB | PROGNOSTIC IMPACT | LEUCOVORIN | ONCOLOGY | MICROSATELLITE INSTABILITY | MUTATION | OXALIPLATIN | KRAS | BRAF | FLUOROURACIL | Index Medicus | Brief Report | Online First | Research
Journal Article
by Korkut, Anil and Zaidi, Sobia and Kanchi, Rupa S and Rao, Shuyun and Gough, Nancy R and Gough, Nancy R and Schultz, Andre and Li, Xubin and Lorenzi, Philip L and Berger, Ashton C and Berger, Ashton C and Robertson, Gordon and Kwong, Lawrence N and Datto, Mike and Roszik, Jason and Ling, Shiyun and Ling, Shiyun and Ravikumar, Visweswaran and Manyam, Ganiraju and Rao, Arvind and Shelley, Simon and Liu, Yuexin and Liu, Yuexin and Ju, Zhenlin and Hansel, Donna and Hansel, Donna and de Velasco, Guillermo and de Velasco, Guillermo and Pennathur, Arjun and Andersen, Jesper B and O'Rourke, Colm J and Ohshiro, Kazufumi and Jogunoori, Wilma and Jogunoori, Wilma and Nguyen, Bao-Ngoc and Li, Shulin and Li, Shulin and Osmanbeyoglu, Hatice U and Osmanbeyoglu, Hatice U and Ajani, Jaffer A and Ajani, Jaffer A and Mani, Sendurai A and Houseman, Andres and Wiznerowicz, Maciej and Wiznerowicz, Maciej and Chen, Jian and Chen, Jian and Gu, Shoujun and Ma, Wencai and Zhang, Jiexin and Tong, Pan and Cherniack, Andrew D and Cherniack, Andrew D and Deng, Chuxia and Deng, Chuxia and Resar, Linda and Resar, Linda and Caesar-Johnson, Samantha J and Weinstein, John N and Demchok, John A and Felau, Ina and Mishra, Lopa and Kasapi, Melpomeni and Akbani, Rehan and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Chudamani, Sudha and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Zhang, Hailei and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell Systems, ISSN 2405-4712, 10/2018, Volume 7, Issue 4, pp. 422 - 437.e7
We present an integromic analysis of gene alterations that modulate transforming growth factor β (TGF-β)-Smad-mediated signaling in 9,125 tumor samples across... 
TGF-β pathway | transcription | DNA methylation | microRNA | TGF-β | cancer | Pan-Cancer | mutation hotspot | TCGA | The Cancer Genome Atlas | ARRAY | MECHANISM | TUMOR SUPPRESSION | SEARCH | BIOCHEMISTRY & MOLECULAR BIOLOGY | PATTERNS | HMGA2 | GENERATION | MUTATIONS | CELL BIOLOGY | mutation | PanCancer | The Cancer Genome Atlas (TCGA)
Journal Article